JPS5750946A - Novel anthranilic acid derivative - Google Patents

Novel anthranilic acid derivative

Info

Publication number
JPS5750946A
JPS5750946A JP12752880A JP12752880A JPS5750946A JP S5750946 A JPS5750946 A JP S5750946A JP 12752880 A JP12752880 A JP 12752880A JP 12752880 A JP12752880 A JP 12752880A JP S5750946 A JPS5750946 A JP S5750946A
Authority
JP
Japan
Prior art keywords
formula
agent
expressed
acid derivative
compound expressed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP12752880A
Other languages
Japanese (ja)
Inventor
Kanji Noda
Akira Nakagawa
Toshiharu Motomura
Hiroyuki Ide
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hisamitsu Pharmaceutical Co Inc
Original Assignee
Hisamitsu Pharmaceutical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co Inc filed Critical Hisamitsu Pharmaceutical Co Inc
Priority to JP12752880A priority Critical patent/JPS5750946A/en
Publication of JPS5750946A publication Critical patent/JPS5750946A/en
Pending legal-status Critical Current

Links

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:An anthranilic acid derivative expressed by formula I (X is H or one or two halogens, lower alkyl, lower alkoxyl or nitro groups substituted at optional positions; R is H or lower alkyl).
EXAMPLE: 2-(o-Carboxybenzyl)-4-chloroanthranilic acid.
USE: An anti-inflammatory agent, antirheumatic agent, antiallergic antihemolytic agent, immunological activator, etc.
PROCESS: A compound expressed by formula III is reacted with an equimolar amount of a compound expressed by formula IV in a solvent, e.g. methanol, to give an intermediate benzylidene derivative expressed by formula II, which is without isolation treated with a reducing agent, e.g. NaBH4 or Pd-C, to afford the compound expressed by formula I. The reducing reaction is carried out at room temperature under heating for 1W10hr.
COPYRIGHT: (C)1982,JPO&Japio
JP12752880A 1980-09-10 1980-09-10 Novel anthranilic acid derivative Pending JPS5750946A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12752880A JPS5750946A (en) 1980-09-10 1980-09-10 Novel anthranilic acid derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12752880A JPS5750946A (en) 1980-09-10 1980-09-10 Novel anthranilic acid derivative

Publications (1)

Publication Number Publication Date
JPS5750946A true JPS5750946A (en) 1982-03-25

Family

ID=14962241

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12752880A Pending JPS5750946A (en) 1980-09-10 1980-09-10 Novel anthranilic acid derivative

Country Status (1)

Country Link
JP (1) JPS5750946A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1226109A4 (en) * 1999-11-05 2005-01-26 Emisphere Tech Inc Phenyl amine carboxylic acid compounds and compositions for delivering active agents

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55145648A (en) * 1979-05-02 1980-11-13 Hisamitsu Pharmaceut Co Inc New derivative of anthranylic acid

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55145648A (en) * 1979-05-02 1980-11-13 Hisamitsu Pharmaceut Co Inc New derivative of anthranylic acid

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1226109A4 (en) * 1999-11-05 2005-01-26 Emisphere Tech Inc Phenyl amine carboxylic acid compounds and compositions for delivering active agents

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