JPS5728064A - Phthalazinone derivative - Google Patents
Phthalazinone derivativeInfo
- Publication number
- JPS5728064A JPS5728064A JP10538980A JP10538980A JPS5728064A JP S5728064 A JPS5728064 A JP S5728064A JP 10538980 A JP10538980 A JP 10538980A JP 10538980 A JP10538980 A JP 10538980A JP S5728064 A JPS5728064 A JP S5728064A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- ulcer
- gastric
- derivative expressed
- inhibiting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- IJAPPYDYQCXOEF-UHFFFAOYSA-N phthalazin-1(2H)-one Chemical class C1=CC=C2C(=O)NN=CC2=C1 IJAPPYDYQCXOEF-UHFFFAOYSA-N 0.000 title abstract 2
- 208000025865 Ulcer Diseases 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 231100000397 ulcer Toxicity 0.000 abstract 2
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 abstract 1
- 206010020601 Hyperchlorhydria Diseases 0.000 abstract 1
- -1 N-Cyano-S-methyl-N'-[ 3-( 1-oxo-4-phenyl-2-phthalazinyl )propyl ]isothiourea Chemical compound 0.000 abstract 1
- 208000008469 Peptic Ulcer Diseases 0.000 abstract 1
- 208000007107 Stomach Ulcer Diseases 0.000 abstract 1
- 229960001138 acetylsalicylic acid Drugs 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000001816 cooling Methods 0.000 abstract 1
- FKTUXVQEOXYNMO-UHFFFAOYSA-N cyanocarbamodithioic acid Chemical class SC(=S)NC#N FKTUXVQEOXYNMO-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000000718 duodenal ulcer Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 210000004051 gastric juice Anatomy 0.000 abstract 1
- 201000005917 gastric ulcer Diseases 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10538980A JPS5728064A (en) | 1980-07-29 | 1980-07-29 | Phthalazinone derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10538980A JPS5728064A (en) | 1980-07-29 | 1980-07-29 | Phthalazinone derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5728064A true JPS5728064A (en) | 1982-02-15 |
| JPS6338996B2 JPS6338996B2 (enrdf_load_html_response) | 1988-08-03 |
Family
ID=14406288
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10538980A Granted JPS5728064A (en) | 1980-07-29 | 1980-07-29 | Phthalazinone derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5728064A (enrdf_load_html_response) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0309765A3 (en) * | 1987-09-30 | 1990-09-26 | Fisons Corporation | 1(2h)-phthalazinones as cytoprotective agents |
-
1980
- 1980-07-29 JP JP10538980A patent/JPS5728064A/ja active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0309765A3 (en) * | 1987-09-30 | 1990-09-26 | Fisons Corporation | 1(2h)-phthalazinones as cytoprotective agents |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6338996B2 (enrdf_load_html_response) | 1988-08-03 |
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