JPS572256A - Benzylideneaminocarboxylic acid derivative and its preparation - Google Patents
Benzylideneaminocarboxylic acid derivative and its preparationInfo
- Publication number
- JPS572256A JPS572256A JP7505580A JP7505580A JPS572256A JP S572256 A JPS572256 A JP S572256A JP 7505580 A JP7505580 A JP 7505580A JP 7505580 A JP7505580 A JP 7505580A JP S572256 A JPS572256 A JP S572256A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound shown
- trans
- methoxy
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- CFEOOIPZYSHGSG-UHFFFAOYSA-N benzylidenecarbamic acid Chemical class OC(=O)N=CC1=CC=CC=C1 CFEOOIPZYSHGSG-UHFFFAOYSA-N 0.000 title 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 2
- UAFHRUBCOQPFFM-UHFFFAOYSA-N 1-(aminomethyl)cyclohexane-1-carboxylic acid Chemical compound NCC1(C(O)=O)CCCCC1 UAFHRUBCOQPFFM-UHFFFAOYSA-N 0.000 abstract 1
- 206010008190 Cerebrovascular accident Diseases 0.000 abstract 1
- NZNMSOFKMUBTKW-UHFFFAOYSA-N Cyclohexanecarboxylic acid Natural products OC(=O)C1CCCCC1 NZNMSOFKMUBTKW-UHFFFAOYSA-N 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 208000006011 Stroke Diseases 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- VZFUCHSFHOYXIS-UHFFFAOYSA-N cycloheptane carboxylic acid Natural products OC(=O)C1CCCCCC1 VZFUCHSFHOYXIS-UHFFFAOYSA-N 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- -1 e.g. Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000011261 inert gas Substances 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 210000000265 leukocyte Anatomy 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000005012 migration Effects 0.000 abstract 1
- 238000013508 migration Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7505580A JPS572256A (en) | 1980-06-04 | 1980-06-04 | Benzylideneaminocarboxylic acid derivative and its preparation |
| US06/267,249 US4377594A (en) | 1980-06-04 | 1981-05-26 | Derivative of 4-(N-(substituted-benzylidene)amino-methyl cyclohexane-1-carboxylic acid |
| ZA00813532A ZA813532B (en) | 1980-06-04 | 1981-05-26 | Derivative of 4-(n-(substituted-benzylidene)amino-methyl)cyclohexane-1-carboxylic acid |
| US06/267,250 US4382955A (en) | 1980-06-04 | 1981-05-26 | Derivative of 4-(N-(3,4-dihydroxybenzylidene) aminomethyl cyclohexane-1-carboxylic acid |
| ZA00813594A ZA813594B (en) | 1980-06-04 | 1981-05-27 | Derivative of 4-(n-(3,4-dihydroxybenzylidene)aminomethyl)cyclohexane-1-carboxylic acid |
| AU71169/81A AU538938B2 (en) | 1980-06-04 | 1981-05-29 | 4-(n-(3:,4:-dihydroxybenzylidene)aminoethyl)cyclohexane- 1-carboxylic acid |
| AU71168/81A AU542972B2 (en) | 1980-06-04 | 1981-05-29 | 4-(n-(substituted-benzylidene)aminomethyl)cyclohexane-1- carboxylic acids |
| NO811887A NO152252C (no) | 1980-06-04 | 1981-06-03 | Analogifremgangsmaate for fremstilling av terapeutisk virksomme derivater av 4-(n-(substituert-benzyliden)aminometyl)-cykloheksan-1-karboksylsyre |
| EP81302467A EP0041827B1 (en) | 1980-06-04 | 1981-06-03 | A n-(benzylidene) aminomethyl-cyclohexane-carboxylic acid |
| EP81302466A EP0041826B1 (en) | 1980-06-04 | 1981-06-03 | 4-(n-(substituted-benzylidene)aminomethyl)cyclohexane-1-carboxylic acids |
| DE8181302467T DE3162772D1 (de) | 1980-06-04 | 1981-06-03 | A n-(benzylidene) aminomethyl-cyclohexane-carboxylic acid |
| CA000378962A CA1183151A (en) | 1980-06-04 | 1981-06-03 | Derivative of 4-[n-(3',4'- dihydroxybenzylidene)aminomethyl]cyclohexane-1- carboxylic acid |
| CA000378938A CA1183150A (en) | 1980-06-04 | 1981-06-03 | Derivative of 4-[n-(substituted- benzylidene)aminomethyl]cyclohexane-1-carboxylic acid |
| NO811888A NO152253C (no) | 1980-06-04 | 1981-06-03 | Analogifremgangsmaate for fremstlling av 4-(n-(3`,4`-dihydroksybenzyliden)aminometyl)-cykloheksan-1-karboksylsyre med terapeutisk aktivitet |
| DE8181302466T DE3161771D1 (en) | 1980-06-04 | 1981-06-03 | 4-(n-(substituted-benzylidene)aminomethyl)cyclohexane-1-carboxylic acids |
| DK248081A DK152649C (da) | 1980-06-04 | 1981-06-04 | Analogifremgangsmaade til fremstilling af en 4-oen-(3',4'-dihydroxybenzyliden)-aminomethylaacyklohexan-1-carboxylsyre og derivater deraf |
| DK248181A DK149769C (da) | 1980-06-04 | 1981-06-04 | Analogifremgangsmaade til fremstilling af trans-4-(n-(substitueret-benzyliden)aminomethyl)-cyklohexan-1-carboxylsyre og derivater heraf |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7505580A JPS572256A (en) | 1980-06-04 | 1980-06-04 | Benzylideneaminocarboxylic acid derivative and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS572256A true JPS572256A (en) | 1982-01-07 |
| JPS6312055B2 JPS6312055B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1988-03-17 |
Family
ID=13565128
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP7505580A Granted JPS572256A (en) | 1980-06-04 | 1980-06-04 | Benzylideneaminocarboxylic acid derivative and its preparation |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JPS572256A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) |
| ZA (2) | ZA813532B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4922881A (en) * | 1987-12-29 | 1990-05-08 | Kawasaki Jukogyo Kabushiki Kaisha | Breather device for an internal combustion engine |
-
1980
- 1980-06-04 JP JP7505580A patent/JPS572256A/ja active Granted
-
1981
- 1981-05-26 ZA ZA00813532A patent/ZA813532B/xx unknown
- 1981-05-27 ZA ZA00813594A patent/ZA813594B/xx unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4922881A (en) * | 1987-12-29 | 1990-05-08 | Kawasaki Jukogyo Kabushiki Kaisha | Breather device for an internal combustion engine |
Also Published As
| Publication number | Publication date |
|---|---|
| ZA813532B (en) | 1982-06-30 |
| JPS6312055B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1988-03-17 |
| ZA813594B (en) | 1982-06-30 |
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