JPS57183794A - Thiazolinoazetidinone derivative and its preparation - Google Patents

Thiazolinoazetidinone derivative and its preparation

Info

Publication number
JPS57183794A
JPS57183794A JP56067136A JP6713681A JPS57183794A JP S57183794 A JPS57183794 A JP S57183794A JP 56067136 A JP56067136 A JP 56067136A JP 6713681 A JP6713681 A JP 6713681A JP S57183794 A JPS57183794 A JP S57183794A
Authority
JP
Japan
Prior art keywords
compound
formula
derivative
oxy
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56067136A
Other languages
Japanese (ja)
Other versions
JPS6236038B2 (en
Inventor
Shigeru Torii
Hideo Tanaka
Junzo Nogami
Takashi Shiroi
Michio Sasaoka
Norio Saito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Chemical Co Ltd
Otsuka Kagaku Yakuhin KK
Original Assignee
Otsuka Chemical Co Ltd
Otsuka Kagaku Yakuhin KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Chemical Co Ltd, Otsuka Kagaku Yakuhin KK filed Critical Otsuka Chemical Co Ltd
Priority to JP56067136A priority Critical patent/JPS57183794A/en
Priority to US06/370,034 priority patent/US4482491A/en
Priority to GB08212330A priority patent/GB2101986B/en
Priority to FR8207398A priority patent/FR2504927B1/en
Priority to DE3249934A priority patent/DE3249934C2/de
Priority to DE3249933A priority patent/DE3249933C2/en
Priority to DE3216256A priority patent/DE3216256A1/en
Publication of JPS57183794A publication Critical patent/JPS57183794A/en
Priority to FR8220933A priority patent/FR2522662B1/en
Priority to US06/625,621 priority patent/US4603014A/en
Priority to GB08418485A priority patent/GB2144418B/en
Priority to GB08500025A priority patent/GB2152051B/en
Publication of JPS6236038B2 publication Critical patent/JPS6236038B2/ja
Granted legal-status Critical Current

Links

Abstract

NEW MATERIAL:The compound of formula I [R1 is aryl(oxy); R2 is aryl(oxy) lower alkyl which may have nitro group on the phenyl ring, or (halogen-substituted) lower alkyl; X1 and X2 are H or halogen].
USE: Synthetic intermediate of penicillin- or cephalosporin-type antibiotic substance useful as an antibacterial agent.
PROCESS: A chlorinated thiazolinoazetidinone derivative of formula IV (novel compound) is prepared, e.g. by the electrolytic halogenation of the compound of formula II with the compound of formula III in a mixture of water and an organic solvent, in the presence of a hydrohalogenic acid, etc. The derivative is used as a starting material, and made to react with preferably 1W5 times mole of a basic compound (preferably an organic amine such as dimethylamine) to obtain the objective compound of formula I.
COPYRIGHT: (C)1982,JPO&Japio
JP56067136A 1981-05-01 1981-05-01 Thiazolinoazetidinone derivative and its preparation Granted JPS57183794A (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
JP56067136A JPS57183794A (en) 1981-05-01 1981-05-01 Thiazolinoazetidinone derivative and its preparation
US06/370,034 US4482491A (en) 1981-05-01 1982-04-20 Thiazolinoazetidinone derivatives and process for the preparation of the same
GB08212330A GB2101986B (en) 1981-05-01 1982-04-28 Thiazolinoazetidinone derivatives
FR8207398A FR2504927B1 (en) 1981-05-01 1982-04-29 THIAZOLINOAZETIDINONE DERIVATIVES, METHODS FOR THEIR PREPARATIONS AND THEIR USE IN THE PREPARATION OF CEPHALOSPORINS
DE3249933A DE3249933C2 (en) 1981-05-01 1982-04-30 Process for the preparation of 2- [4- (aryl or heteroaryldithio) -2-azetidinon-1-yl] -3-halomethyl-3-butenoic acid derivatives
DE3249934A DE3249934C2 (en) 1981-05-01 1982-04-30
DE3216256A DE3216256A1 (en) 1981-05-01 1982-04-30 THIAZOLINOAZETIDINE DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF
FR8220933A FR2522662B1 (en) 1981-05-01 1982-12-14 PROCESS FOR THE PREPARATION OF CEPHALOSPORINS
US06/625,621 US4603014A (en) 1981-05-01 1984-06-28 Thiazolinoazetidinone derivatives and process for the preparation of the same
GB08418485A GB2144418B (en) 1981-05-01 1984-07-19 Thiazolinoazetidinone derivatives and process for the preparation of the same
GB08500025A GB2152051B (en) 1981-05-01 1985-01-02 Process for the preparation of azetidinone derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56067136A JPS57183794A (en) 1981-05-01 1981-05-01 Thiazolinoazetidinone derivative and its preparation

Publications (2)

Publication Number Publication Date
JPS57183794A true JPS57183794A (en) 1982-11-12
JPS6236038B2 JPS6236038B2 (en) 1987-08-05

Family

ID=13336177

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56067136A Granted JPS57183794A (en) 1981-05-01 1981-05-01 Thiazolinoazetidinone derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS57183794A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57185295A (en) * 1981-05-08 1982-11-15 Otsuka Chem Co Ltd Thiazolinoazetidinone derivative and its preparation

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57185295A (en) * 1981-05-08 1982-11-15 Otsuka Chem Co Ltd Thiazolinoazetidinone derivative and its preparation
JPS632435B2 (en) * 1981-05-08 1988-01-19 Ootsuka Kagaku Kk

Also Published As

Publication number Publication date
JPS6236038B2 (en) 1987-08-05

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