JPS57183794A - Thiazolinoazetidinone derivative and its preparation - Google Patents
Thiazolinoazetidinone derivative and its preparationInfo
- Publication number
- JPS57183794A JPS57183794A JP56067136A JP6713681A JPS57183794A JP S57183794 A JPS57183794 A JP S57183794A JP 56067136 A JP56067136 A JP 56067136A JP 6713681 A JP6713681 A JP 6713681A JP S57183794 A JPS57183794 A JP S57183794A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- derivative
- oxy
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
NEW MATERIAL:The compound of formula I [R1 is aryl(oxy); R2 is aryl(oxy) lower alkyl which may have nitro group on the phenyl ring, or (halogen-substituted) lower alkyl; X1 and X2 are H or halogen].
USE: Synthetic intermediate of penicillin- or cephalosporin-type antibiotic substance useful as an antibacterial agent.
PROCESS: A chlorinated thiazolinoazetidinone derivative of formula IV (novel compound) is prepared, e.g. by the electrolytic halogenation of the compound of formula II with the compound of formula III in a mixture of water and an organic solvent, in the presence of a hydrohalogenic acid, etc. The derivative is used as a starting material, and made to react with preferably 1W5 times mole of a basic compound (preferably an organic amine such as dimethylamine) to obtain the objective compound of formula I.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56067136A JPS57183794A (en) | 1981-05-01 | 1981-05-01 | Thiazolinoazetidinone derivative and its preparation |
US06/370,034 US4482491A (en) | 1981-05-01 | 1982-04-20 | Thiazolinoazetidinone derivatives and process for the preparation of the same |
GB08212330A GB2101986B (en) | 1981-05-01 | 1982-04-28 | Thiazolinoazetidinone derivatives |
FR8207398A FR2504927B1 (en) | 1981-05-01 | 1982-04-29 | THIAZOLINOAZETIDINONE DERIVATIVES, METHODS FOR THEIR PREPARATIONS AND THEIR USE IN THE PREPARATION OF CEPHALOSPORINS |
DE3249933A DE3249933C2 (en) | 1981-05-01 | 1982-04-30 | Process for the preparation of 2- [4- (aryl or heteroaryldithio) -2-azetidinon-1-yl] -3-halomethyl-3-butenoic acid derivatives |
DE3249934A DE3249934C2 (en) | 1981-05-01 | 1982-04-30 | |
DE3216256A DE3216256A1 (en) | 1981-05-01 | 1982-04-30 | THIAZOLINOAZETIDINE DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF |
FR8220933A FR2522662B1 (en) | 1981-05-01 | 1982-12-14 | PROCESS FOR THE PREPARATION OF CEPHALOSPORINS |
US06/625,621 US4603014A (en) | 1981-05-01 | 1984-06-28 | Thiazolinoazetidinone derivatives and process for the preparation of the same |
GB08418485A GB2144418B (en) | 1981-05-01 | 1984-07-19 | Thiazolinoazetidinone derivatives and process for the preparation of the same |
GB08500025A GB2152051B (en) | 1981-05-01 | 1985-01-02 | Process for the preparation of azetidinone derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56067136A JPS57183794A (en) | 1981-05-01 | 1981-05-01 | Thiazolinoazetidinone derivative and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57183794A true JPS57183794A (en) | 1982-11-12 |
JPS6236038B2 JPS6236038B2 (en) | 1987-08-05 |
Family
ID=13336177
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56067136A Granted JPS57183794A (en) | 1981-05-01 | 1981-05-01 | Thiazolinoazetidinone derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57183794A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57185295A (en) * | 1981-05-08 | 1982-11-15 | Otsuka Chem Co Ltd | Thiazolinoazetidinone derivative and its preparation |
-
1981
- 1981-05-01 JP JP56067136A patent/JPS57183794A/en active Granted
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57185295A (en) * | 1981-05-08 | 1982-11-15 | Otsuka Chem Co Ltd | Thiazolinoazetidinone derivative and its preparation |
JPS632435B2 (en) * | 1981-05-08 | 1988-01-19 | Ootsuka Kagaku Kk |
Also Published As
Publication number | Publication date |
---|---|
JPS6236038B2 (en) | 1987-08-05 |
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