JPS57185295A - Thiazolinoazetidinone derivative and its preparation - Google Patents

Thiazolinoazetidinone derivative and its preparation

Info

Publication number
JPS57185295A
JPS57185295A JP56069687A JP6968781A JPS57185295A JP S57185295 A JPS57185295 A JP S57185295A JP 56069687 A JP56069687 A JP 56069687A JP 6968781 A JP6968781 A JP 6968781A JP S57185295 A JPS57185295 A JP S57185295A
Authority
JP
Japan
Prior art keywords
formula
thiazolinoazetidinone
derivative shown
give
reacted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56069687A
Other languages
Japanese (ja)
Other versions
JPS632435B2 (en
Inventor
Shigeru Torii
Hideo Tanaka
Junzo Nogami
Norio Saito
Takashi Shiroi
Michio Sasaoka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Chemical Co Ltd
Otsuka Kagaku Yakuhin KK
Original Assignee
Otsuka Chemical Co Ltd
Otsuka Kagaku Yakuhin KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Chemical Co Ltd, Otsuka Kagaku Yakuhin KK filed Critical Otsuka Chemical Co Ltd
Priority to JP56069687A priority Critical patent/JPS57185295A/en
Priority to US06/370,034 priority patent/US4482491A/en
Priority to GB08212330A priority patent/GB2101986B/en
Priority to FR8207398A priority patent/FR2504927B1/en
Priority to DE3216256A priority patent/DE3216256A1/en
Priority to DE3249934A priority patent/DE3249934C2/de
Priority to DE3249933A priority patent/DE3249933C2/en
Publication of JPS57185295A publication Critical patent/JPS57185295A/en
Priority to FR8220933A priority patent/FR2522662B1/en
Priority to US06/625,621 priority patent/US4603014A/en
Priority to GB08418485A priority patent/GB2144418B/en
Priority to GB08500025A priority patent/GB2152051B/en
Publication of JPS632435B2 publication Critical patent/JPS632435B2/ja
Granted legal-status Critical Current

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  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

NEW MATERIAL:A derivative shown by the formulaI[R1 is aryl(oxy); R2 is a group shown by the formula II, III, or IV; R3 is aryl(oxy) lower alkyl or lower alkyl].
USE: An intermediate for synthesizing antibiotics of the penicillin or cephalosporin type.
PROCESS: For example, a compound shown by the formula V is electrolyzed in a mixed solvent in the presence of hydrochloric acid or chloride (e.g., methylene chloride, etc.) at 20W100°C to give a novel thiazolinoazetidinone chloride derivative shown by the formula VI, which is reacted with chlorine under irradiation of light in a solvent at -20W100°C to give a thiazolinoazetidinone derivative shown by the formula VII. The derivative shown by the formula VII is further reacted with a basic compound (e.g., triethylamine, etc.) with stirring at -20W 80°C, to give a thiazolinoazetidinone derivative shown by the formula VIII, which is reacted with zinc in the presence of acetic acid in a solvent at -50W30°C with stirring.
COPYRIGHT: (C)1982,JPO&Japio
JP56069687A 1981-05-01 1981-05-08 Thiazolinoazetidinone derivative and its preparation Granted JPS57185295A (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
JP56069687A JPS57185295A (en) 1981-05-08 1981-05-08 Thiazolinoazetidinone derivative and its preparation
US06/370,034 US4482491A (en) 1981-05-01 1982-04-20 Thiazolinoazetidinone derivatives and process for the preparation of the same
GB08212330A GB2101986B (en) 1981-05-01 1982-04-28 Thiazolinoazetidinone derivatives
FR8207398A FR2504927B1 (en) 1981-05-01 1982-04-29 THIAZOLINOAZETIDINONE DERIVATIVES, METHODS FOR THEIR PREPARATIONS AND THEIR USE IN THE PREPARATION OF CEPHALOSPORINS
DE3249934A DE3249934C2 (en) 1981-05-01 1982-04-30
DE3216256A DE3216256A1 (en) 1981-05-01 1982-04-30 THIAZOLINOAZETIDINE DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF
DE3249933A DE3249933C2 (en) 1981-05-01 1982-04-30 Process for the preparation of 2- [4- (aryl or heteroaryldithio) -2-azetidinon-1-yl] -3-halomethyl-3-butenoic acid derivatives
FR8220933A FR2522662B1 (en) 1981-05-01 1982-12-14 PROCESS FOR THE PREPARATION OF CEPHALOSPORINS
US06/625,621 US4603014A (en) 1981-05-01 1984-06-28 Thiazolinoazetidinone derivatives and process for the preparation of the same
GB08418485A GB2144418B (en) 1981-05-01 1984-07-19 Thiazolinoazetidinone derivatives and process for the preparation of the same
GB08500025A GB2152051B (en) 1981-05-01 1985-01-02 Process for the preparation of azetidinone derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56069687A JPS57185295A (en) 1981-05-08 1981-05-08 Thiazolinoazetidinone derivative and its preparation

Publications (2)

Publication Number Publication Date
JPS57185295A true JPS57185295A (en) 1982-11-15
JPS632435B2 JPS632435B2 (en) 1988-01-19

Family

ID=13410024

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56069687A Granted JPS57185295A (en) 1981-05-01 1981-05-08 Thiazolinoazetidinone derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS57185295A (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55147293A (en) * 1979-04-30 1980-11-17 Lilly Co Eli Novel thiazolinoazetidinone compound
JPS57183793A (en) * 1981-05-01 1982-11-12 Otsuka Chem Co Ltd Chlorinated thiazolinoazetidinone derivative and its preparation
JPS57183794A (en) * 1981-05-01 1982-11-12 Otsuka Chem Co Ltd Thiazolinoazetidinone derivative and its preparation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55147293A (en) * 1979-04-30 1980-11-17 Lilly Co Eli Novel thiazolinoazetidinone compound
JPS57183793A (en) * 1981-05-01 1982-11-12 Otsuka Chem Co Ltd Chlorinated thiazolinoazetidinone derivative and its preparation
JPS57183794A (en) * 1981-05-01 1982-11-12 Otsuka Chem Co Ltd Thiazolinoazetidinone derivative and its preparation

Also Published As

Publication number Publication date
JPS632435B2 (en) 1988-01-19

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