JPS57179129A - Cyclopentene derivative and its preparation - Google Patents

Info

Publication number

JPS57179129A

JPS57179129A JP6506081A JP6506081A JPS57179129A JP S57179129 A JPS57179129 A JP S57179129A JP 6506081 A JP6506081 A JP 6506081A JP 6506081 A JP6506081 A JP 6506081A JP S57179129 A JPS57179129 A JP S57179129A

Authority

JP

Japan

Prior art keywords

formula

compound

preparation

cyclopentene

lower alkyl

Prior art date

1981-04-28

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

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• 125000002433 cyclopentenyl group Chemical class C1(=CCCC1)* 0.000 title abstract 2
• RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 3
• VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 abstract 3
• -1 5-Hydroxy-5-(1-hydroxyethyl)-1-methyl-cyclopentene Chemical compound 0.000 abstract 2
• RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 abstract 2
• 125000000217 alkyl group Chemical group 0.000 abstract 2
• HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
• 150000001875 compounds Chemical class 0.000 abstract 2
• JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 abstract 2
• BZKFMUIJRXWWQK-UHFFFAOYSA-N Cyclopentenone Chemical compound O=C1CCC=C1 BZKFMUIJRXWWQK-UHFFFAOYSA-N 0.000 abstract 1
• 230000002378 acidificating effect Effects 0.000 abstract 1
• 235000012000 cholesterol Nutrition 0.000 abstract 1
• 229940107161 cholesterol Drugs 0.000 abstract 1
• 229940079593 drug Drugs 0.000 abstract 1
• 239000003814 drug Substances 0.000 abstract 1
• 229960000890 hydrocortisone Drugs 0.000 abstract 1
• 230000003301 hydrolyzing effect Effects 0.000 abstract 1
• 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
• 150000002576 ketones Chemical class 0.000 abstract 1
• 239000000463 material Substances 0.000 abstract 1
• 229910052987 metal hydride Inorganic materials 0.000 abstract 1
• 150000004681 metal hydrides Chemical class 0.000 abstract 1
• 229960003387 progesterone Drugs 0.000 abstract 1
• 239000000186 progesterone Substances 0.000 abstract 1
• 239000002904 solvent Substances 0.000 abstract 1
• 150000003431 steroids Chemical class 0.000 abstract 1
• LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
• PGOLTJPQCISRTO-UHFFFAOYSA-N vinyllithium Chemical compound [Li]C=C PGOLTJPQCISRTO-UHFFFAOYSA-N 0.000 abstract 1
• 239000011647 vitamin D3 Substances 0.000 abstract 1
• QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 abstract 1