JPS5589297A - Prostaglandin derivative, its preparation and its drug - Google Patents
Prostaglandin derivative, its preparation and its drugInfo
- Publication number
- JPS5589297A JPS5589297A JP16366778A JP16366778A JPS5589297A JP S5589297 A JPS5589297 A JP S5589297A JP 16366778 A JP16366778 A JP 16366778A JP 16366778 A JP16366778 A JP 16366778A JP S5589297 A JPS5589297 A JP S5589297A
- Authority
- JP
- Japan
- Prior art keywords
- drug
- prostaglandin
- benzoyloxy
- acetoxy
- trans
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
NEW MATERIAL:The title compound shown by the formula I [OR is acetoxy, benzoyloxy, etc; n is 1W3; m is 0 or 1; PG is prostaglandin; except for the case where n is 1, m is 1, PG is 9α, 11α, 15α-triacetoxy-5(cis)-13(trans)-prostagenoyl, and OR is acetoxy or hydroxy].
EXAMPLE: 3-Benzoyloxy-1, 3, 5(10)-estratiene-17β-oxycarbonylmethyl 11α, 15α- dihydroxy-9-oxo-13(trans)-prostenoate.
USE: An inducer of obortion and delivery for pregnant mammals, a fertilizing drug, a sexual excitement requlator and contraceptive pill, and a menses inducer for female mammals.
PROCESS: The X group of an estradiol derivative shown by the formula II is combined with the carboxylic acid group of a prostaglandin by ester bonds.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16366778A JPS5589297A (en) | 1978-12-28 | 1978-12-28 | Prostaglandin derivative, its preparation and its drug |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16366778A JPS5589297A (en) | 1978-12-28 | 1978-12-28 | Prostaglandin derivative, its preparation and its drug |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5589297A true JPS5589297A (en) | 1980-07-05 |
JPS611032B2 JPS611032B2 (en) | 1986-01-13 |
Family
ID=15778292
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP16366778A Granted JPS5589297A (en) | 1978-12-28 | 1978-12-28 | Prostaglandin derivative, its preparation and its drug |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5589297A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1028720A1 (en) * | 1997-10-20 | 2000-08-23 | Asivi, LLC | Methods, compositions, and kits for enhancing female sexual desire and responsiveness |
US6486207B2 (en) | 1998-12-10 | 2002-11-26 | Nexmed (Holdings), Inc. | Compositions and methods for amelioration of human female sexual dysfunction |
US6825234B2 (en) | 1998-12-10 | 2004-11-30 | Nexmed (Holdings) , Inc. | Compositions and methods for amelioration of human female sexual dysfunction |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6379491U (en) * | 1986-11-12 | 1988-05-25 |
-
1978
- 1978-12-28 JP JP16366778A patent/JPS5589297A/en active Granted
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1028720A1 (en) * | 1997-10-20 | 2000-08-23 | Asivi, LLC | Methods, compositions, and kits for enhancing female sexual desire and responsiveness |
EP1028720A4 (en) * | 1997-10-20 | 2006-02-08 | Vivus Inc | Methods, compositions, and kits for enhancing female sexual desire and responsiveness |
US6486207B2 (en) | 1998-12-10 | 2002-11-26 | Nexmed (Holdings), Inc. | Compositions and methods for amelioration of human female sexual dysfunction |
US6825234B2 (en) | 1998-12-10 | 2004-11-30 | Nexmed (Holdings) , Inc. | Compositions and methods for amelioration of human female sexual dysfunction |
Also Published As
Publication number | Publication date |
---|---|
JPS611032B2 (en) | 1986-01-13 |
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