JPS5785380A - Thiazolidone derivative - Google Patents

Thiazolidone derivative

Info

Publication number
JPS5785380A
JPS5785380A JP16291080A JP16291080A JPS5785380A JP S5785380 A JPS5785380 A JP S5785380A JP 16291080 A JP16291080 A JP 16291080A JP 16291080 A JP16291080 A JP 16291080A JP S5785380 A JPS5785380 A JP S5785380A
Authority
JP
Japan
Prior art keywords
compound expressed
formula
thiazolidone
expressed
reacted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP16291080A
Other languages
Japanese (ja)
Other versions
JPH0144707B2 (en
Inventor
Kanji Noda
Akira Nakagawa
Toshiharu Motomura
Masayoshi Tsuji
Yuji Shimozono
Hiroyuki Ide
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hisamitsu Pharmaceutical Co Inc
Original Assignee
Hisamitsu Pharmaceutical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co Inc filed Critical Hisamitsu Pharmaceutical Co Inc
Priority to JP16291080A priority Critical patent/JPS5785380A/en
Publication of JPS5785380A publication Critical patent/JPS5785380A/en
Publication of JPH0144707B2 publication Critical patent/JPH0144707B2/ja
Granted legal-status Critical Current

Links

Abstract

NEW MATERIAL:A thiazolidone derivative expressed by formulaI(R is H or CH3; R1 is H or lower alkyl; A is aryl or pyridyl).
EXAMPLE: 2-Phenyl-3-[trans-4-(carboxy)cyclohexylmethyl]-4-thiazolidone.
USE: A preventing agent and remedy for allergic diseases, e.g. nephritis, rheumatism, collagen diseases or autoimmune diseases, having more remarkable anticomplementary action than tranexamic acid, and an anti-inflammatory agent.
PROCESS: A compound expressed by formula II is reacted with a compound expressed by formula III in a solvent, e.g. methyl alcohol, under heating and refluxing to give a compound expressed by formula IV, which is then reacted with a compound expressed by formula V (R2 is H or ester residue) to afford the compound expressed by formulaIin high yield.
COPYRIGHT: (C)1982,JPO&Japio
JP16291080A 1980-11-18 1980-11-18 Thiazolidone derivative Granted JPS5785380A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16291080A JPS5785380A (en) 1980-11-18 1980-11-18 Thiazolidone derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16291080A JPS5785380A (en) 1980-11-18 1980-11-18 Thiazolidone derivative

Publications (2)

Publication Number Publication Date
JPS5785380A true JPS5785380A (en) 1982-05-28
JPH0144707B2 JPH0144707B2 (en) 1989-09-29

Family

ID=15763546

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16291080A Granted JPS5785380A (en) 1980-11-18 1980-11-18 Thiazolidone derivative

Country Status (1)

Country Link
JP (1) JPS5785380A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4992455A (en) * 1987-05-22 1991-02-12 Sumitomo Pharmaceuticals Company, Limited Thiazolidin-4-one derivatives useful for treating diseases caused by platelet activating factor
US5021435A (en) * 1988-01-22 1991-06-04 Sumitomo Pharmaceuticals Company, Limited Certain pyridyl-thiazolidin-4-one having anti-ulcer activity
EP0722729A2 (en) * 1995-01-23 1996-07-24 Eli Lilly And Company Aryl-substituted rhodanines for treating multiple sclerosis
US6506751B1 (en) 1999-11-12 2003-01-14 Millennium Pharmaceuticals, Inc. Thiazolidinone compounds useful as chemokine inhibitors
WO2004017965A1 (en) * 2002-08-23 2004-03-04 Ionix Pharmaceuticals Limited 1,3-thiazolin-4-ones as therapeutic compounds in the treatment of pain

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4992455A (en) * 1987-05-22 1991-02-12 Sumitomo Pharmaceuticals Company, Limited Thiazolidin-4-one derivatives useful for treating diseases caused by platelet activating factor
US5021435A (en) * 1988-01-22 1991-06-04 Sumitomo Pharmaceuticals Company, Limited Certain pyridyl-thiazolidin-4-one having anti-ulcer activity
EP0722729A2 (en) * 1995-01-23 1996-07-24 Eli Lilly And Company Aryl-substituted rhodanines for treating multiple sclerosis
EP0722729A3 (en) * 1995-01-23 1997-11-26 Eli Lilly And Company Aryl-substituted rhodanines for treating multiple sclerosis
US6506751B1 (en) 1999-11-12 2003-01-14 Millennium Pharmaceuticals, Inc. Thiazolidinone compounds useful as chemokine inhibitors
WO2004017965A1 (en) * 2002-08-23 2004-03-04 Ionix Pharmaceuticals Limited 1,3-thiazolin-4-ones as therapeutic compounds in the treatment of pain

Also Published As

Publication number Publication date
JPH0144707B2 (en) 1989-09-29

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