JPS54119447A - 19-norsteroid derivatine - Google Patents

19-norsteroid derivatine

Info

Publication number
JPS54119447A
JPS54119447A JP2734578A JP2734578A JPS54119447A JP S54119447 A JPS54119447 A JP S54119447A JP 2734578 A JP2734578 A JP 2734578A JP 2734578 A JP2734578 A JP 2734578A JP S54119447 A JPS54119447 A JP S54119447A
Authority
JP
Japan
Prior art keywords
formula
compound
alkali metal
oxymethylpregna
tetrahydropyranyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2734578A
Other languages
Japanese (ja)
Other versions
JPS617200B2 (en
Inventor
Yoshimi Morita
Tadashi Shirasaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Kasei Corp
Original Assignee
Mitsubishi Kasei Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Kasei Corp filed Critical Mitsubishi Kasei Corp
Priority to JP2734578A priority Critical patent/JPS54119447A/en
Publication of JPS54119447A publication Critical patent/JPS54119447A/en
Publication of JPS617200B2 publication Critical patent/JPS617200B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

NEW MATERIAL:19-Nor-20-(2-tetrahydropyranyl) oxymethylpregna-1, 3, 5 (10)-triene-3-ol of formula I.
USE: An intermediate for the synthesis of medicines having female hormone actions and various steroid medicines.
PROCESS: 20-(2-Tetrahydropyranyl)oxymethylpregna 1,4-diene-3-one of formula II is brought into contact with an adduct of an alkali metal, e.g Li or Na, with a polycyclic aromatic compound, e.g. 1-methylnaphthalene, in an ethereal solvent, e.g. diethyl ether, to form an alkali metal salt of formula IV via the compound of formula III. The by-product methyl alkali metal is decomposed by a scavenger, e.g. diphenylmethane of formula V, and the compound of formula IVthus obtained is brought into contact with an acid, e.g. hydrochloric acid, to give the compound of formula I.
COPYRIGHT: (C)1979,JPO&Japio
JP2734578A 1978-03-10 1978-03-10 19-norsteroid derivatine Granted JPS54119447A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2734578A JPS54119447A (en) 1978-03-10 1978-03-10 19-norsteroid derivatine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2734578A JPS54119447A (en) 1978-03-10 1978-03-10 19-norsteroid derivatine

Publications (2)

Publication Number Publication Date
JPS54119447A true JPS54119447A (en) 1979-09-17
JPS617200B2 JPS617200B2 (en) 1986-03-04

Family

ID=12218448

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2734578A Granted JPS54119447A (en) 1978-03-10 1978-03-10 19-norsteroid derivatine

Country Status (1)

Country Link
JP (1) JPS54119447A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63185399U (en) * 1987-05-21 1988-11-29

Also Published As

Publication number Publication date
JPS617200B2 (en) 1986-03-04

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