JPS54119447A - 19-norsteroid derivatine - Google Patents
19-norsteroid derivatineInfo
- Publication number
- JPS54119447A JPS54119447A JP2734578A JP2734578A JPS54119447A JP S54119447 A JPS54119447 A JP S54119447A JP 2734578 A JP2734578 A JP 2734578A JP 2734578 A JP2734578 A JP 2734578A JP S54119447 A JPS54119447 A JP S54119447A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- alkali metal
- oxymethylpregna
- tetrahydropyranyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
NEW MATERIAL:19-Nor-20-(2-tetrahydropyranyl) oxymethylpregna-1, 3, 5 (10)-triene-3-ol of formula I.
USE: An intermediate for the synthesis of medicines having female hormone actions and various steroid medicines.
PROCESS: 20-(2-Tetrahydropyranyl)oxymethylpregna 1,4-diene-3-one of formula II is brought into contact with an adduct of an alkali metal, e.g Li or Na, with a polycyclic aromatic compound, e.g. 1-methylnaphthalene, in an ethereal solvent, e.g. diethyl ether, to form an alkali metal salt of formula IV via the compound of formula III. The by-product methyl alkali metal is decomposed by a scavenger, e.g. diphenylmethane of formula V, and the compound of formula IVthus obtained is brought into contact with an acid, e.g. hydrochloric acid, to give the compound of formula I.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2734578A JPS54119447A (en) | 1978-03-10 | 1978-03-10 | 19-norsteroid derivatine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2734578A JPS54119447A (en) | 1978-03-10 | 1978-03-10 | 19-norsteroid derivatine |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS54119447A true JPS54119447A (en) | 1979-09-17 |
JPS617200B2 JPS617200B2 (en) | 1986-03-04 |
Family
ID=12218448
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2734578A Granted JPS54119447A (en) | 1978-03-10 | 1978-03-10 | 19-norsteroid derivatine |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS54119447A (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63185399U (en) * | 1987-05-21 | 1988-11-29 |
-
1978
- 1978-03-10 JP JP2734578A patent/JPS54119447A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS617200B2 (en) | 1986-03-04 |
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