JPS54112850A - Steroid derivative and its preparation - Google Patents

Steroid derivative and its preparation

Info

Publication number
JPS54112850A
JPS54112850A JP2014378A JP2014378A JPS54112850A JP S54112850 A JPS54112850 A JP S54112850A JP 2014378 A JP2014378 A JP 2014378A JP 2014378 A JP2014378 A JP 2014378A JP S54112850 A JPS54112850 A JP S54112850A
Authority
JP
Japan
Prior art keywords
formula
preparation
acyloxymethylpregna
triene
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2014378A
Other languages
Japanese (ja)
Other versions
JPS612080B2 (en
Inventor
Yoshimi Morita
Hideaki Kobayashi
Kazunari Kinugasa
Hiroyuki Otani
Tadashi Shirasaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Kasei Corp
Original Assignee
Mitsubishi Kasei Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Kasei Corp filed Critical Mitsubishi Kasei Corp
Priority to JP2014378A priority Critical patent/JPS54112850A/en
Publication of JPS54112850A publication Critical patent/JPS54112850A/en
Publication of JPS612080B2 publication Critical patent/JPS612080B2/ja
Granted legal-status Critical Current

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  • Steroid Compounds (AREA)

Abstract

NEW MATERIAL:A 3-hydroxy-19-nor-20-acyloxymethylpregna-1,3,5(10) triene of formula I.
USE: An intermediate for adrenal cortical hormones and female formone.
PROCESS: A solution of an 20-acyloxymethylpregna-1,4-diene-3-one of formula II: (R is acyl group) in a hydrocarbon, e.g. hexane or pentane, in an amount of 2W50 times that of the compound of formula II, is mixed with a hydrocarbon, e.g. ethane, as a reaction assistant heated at 450W750°C, and thermally decomposed to give a 3-hydroxy-19-nor-20-acyloxy-methylpregna-1,3,5(10)-triene of formula I.
COPYRIGHT: (C)1979,JPO&Japio
JP2014378A 1978-02-23 1978-02-23 Steroid derivative and its preparation Granted JPS54112850A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2014378A JPS54112850A (en) 1978-02-23 1978-02-23 Steroid derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2014378A JPS54112850A (en) 1978-02-23 1978-02-23 Steroid derivative and its preparation

Publications (2)

Publication Number Publication Date
JPS54112850A true JPS54112850A (en) 1979-09-04
JPS612080B2 JPS612080B2 (en) 1986-01-22

Family

ID=12018914

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014378A Granted JPS54112850A (en) 1978-02-23 1978-02-23 Steroid derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS54112850A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001085755A1 (en) * 2000-05-11 2001-11-15 Marsden, John, Christopher 2-substituted pregna-1, 3, 5 (10) -triene and chola-1, 3, 5 (10)-triene derivatives and their biological activity
WO2001058919A3 (en) * 2000-02-11 2002-05-02 Stanford Res Inst Int Synthesis of anti-estrogenic and other therapeutic steroids from 21-hydroxy-19-norpregna-4-en-3-one

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63172380U (en) * 1987-04-28 1988-11-09

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001058919A3 (en) * 2000-02-11 2002-05-02 Stanford Res Inst Int Synthesis of anti-estrogenic and other therapeutic steroids from 21-hydroxy-19-norpregna-4-en-3-one
US6784170B2 (en) 2000-02-11 2004-08-31 Sri International Synthesis of anti-estrogenic and other therapeutic steroids from 21-hydroxy-19-norpregna-4-en-3-one
US7772218B2 (en) 2000-02-11 2010-08-10 Sri International Synthesis of anti-estrogenic and other therapeutic steroids from 21-hydroxy-19-norpregna-4-en-3-one
WO2001085755A1 (en) * 2000-05-11 2001-11-15 Marsden, John, Christopher 2-substituted pregna-1, 3, 5 (10) -triene and chola-1, 3, 5 (10)-triene derivatives and their biological activity
CZ298835B6 (en) * 2000-05-11 2008-02-20 Research Institute For Medicine And Chemistry Inc. 2-Substituted pregnatriene and cholatriene derivatives

Also Published As

Publication number Publication date
JPS612080B2 (en) 1986-01-22

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