JPS54112850A - Steroid derivative and its preparation - Google Patents
Steroid derivative and its preparationInfo
- Publication number
- JPS54112850A JPS54112850A JP2014378A JP2014378A JPS54112850A JP S54112850 A JPS54112850 A JP S54112850A JP 2014378 A JP2014378 A JP 2014378A JP 2014378 A JP2014378 A JP 2014378A JP S54112850 A JPS54112850 A JP S54112850A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- preparation
- acyloxymethylpregna
- triene
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Steroid Compounds (AREA)
Abstract
NEW MATERIAL:A 3-hydroxy-19-nor-20-acyloxymethylpregna-1,3,5(10) triene of formula I.
USE: An intermediate for adrenal cortical hormones and female formone.
PROCESS: A solution of an 20-acyloxymethylpregna-1,4-diene-3-one of formula II: (R is acyl group) in a hydrocarbon, e.g. hexane or pentane, in an amount of 2W50 times that of the compound of formula II, is mixed with a hydrocarbon, e.g. ethane, as a reaction assistant heated at 450W750°C, and thermally decomposed to give a 3-hydroxy-19-nor-20-acyloxy-methylpregna-1,3,5(10)-triene of formula I.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2014378A JPS54112850A (en) | 1978-02-23 | 1978-02-23 | Steroid derivative and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2014378A JPS54112850A (en) | 1978-02-23 | 1978-02-23 | Steroid derivative and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS54112850A true JPS54112850A (en) | 1979-09-04 |
JPS612080B2 JPS612080B2 (en) | 1986-01-22 |
Family
ID=12018914
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014378A Granted JPS54112850A (en) | 1978-02-23 | 1978-02-23 | Steroid derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS54112850A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001085755A1 (en) * | 2000-05-11 | 2001-11-15 | Marsden, John, Christopher | 2-substituted pregna-1, 3, 5 (10) -triene and chola-1, 3, 5 (10)-triene derivatives and their biological activity |
WO2001058919A3 (en) * | 2000-02-11 | 2002-05-02 | Stanford Res Inst Int | Synthesis of anti-estrogenic and other therapeutic steroids from 21-hydroxy-19-norpregna-4-en-3-one |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63172380U (en) * | 1987-04-28 | 1988-11-09 |
-
1978
- 1978-02-23 JP JP2014378A patent/JPS54112850A/en active Granted
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001058919A3 (en) * | 2000-02-11 | 2002-05-02 | Stanford Res Inst Int | Synthesis of anti-estrogenic and other therapeutic steroids from 21-hydroxy-19-norpregna-4-en-3-one |
US6784170B2 (en) | 2000-02-11 | 2004-08-31 | Sri International | Synthesis of anti-estrogenic and other therapeutic steroids from 21-hydroxy-19-norpregna-4-en-3-one |
US7772218B2 (en) | 2000-02-11 | 2010-08-10 | Sri International | Synthesis of anti-estrogenic and other therapeutic steroids from 21-hydroxy-19-norpregna-4-en-3-one |
WO2001085755A1 (en) * | 2000-05-11 | 2001-11-15 | Marsden, John, Christopher | 2-substituted pregna-1, 3, 5 (10) -triene and chola-1, 3, 5 (10)-triene derivatives and their biological activity |
CZ298835B6 (en) * | 2000-05-11 | 2008-02-20 | Research Institute For Medicine And Chemistry Inc. | 2-Substituted pregnatriene and cholatriene derivatives |
Also Published As
Publication number | Publication date |
---|---|
JPS612080B2 (en) | 1986-01-22 |
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