JPS57154132A - Antiallergic agent and its preparation - Google Patents

Antiallergic agent and its preparation

Info

Publication number
JPS57154132A
JPS57154132A JP56038790A JP3879081A JPS57154132A JP S57154132 A JPS57154132 A JP S57154132A JP 56038790 A JP56038790 A JP 56038790A JP 3879081 A JP3879081 A JP 3879081A JP S57154132 A JPS57154132 A JP S57154132A
Authority
JP
Japan
Prior art keywords
liquid
supernatant liquid
antiallergic agent
separated
ethyl alcohol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP56038790A
Other languages
Japanese (ja)
Inventor
Makoto Enomoto
Hideyo Itakura
Yoshio Ueno
Yosuke Kawasaki
Fusae Iida
Hiroko Yoshizawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KIYOKUTOU SHIBOUSAN KK
Kyokuto Fatty-Acid Corp
Original Assignee
KIYOKUTOU SHIBOUSAN KK
Kyokuto Fatty-Acid Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KIYOKUTOU SHIBOUSAN KK, Kyokuto Fatty-Acid Corp filed Critical KIYOKUTOU SHIBOUSAN KK
Priority to JP56038790A priority Critical patent/JPS57154132A/en
Priority to GB8113273A priority patent/GB2077101B/en
Priority to DE19813118148 priority patent/DE3118148A1/en
Priority to FR8109344A priority patent/FR2481927A1/en
Priority to AU78260/81A priority patent/AU7826081A/en
Priority to ZA818531A priority patent/ZA818531B/en
Priority to IT25578/81A priority patent/IT1142095B/en
Priority to NL8105655A priority patent/NL8105655A/en
Publication of JPS57154132A publication Critical patent/JPS57154132A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/04—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/46—Streptococcus ; Enterococcus; Lactococcus

Abstract

PURPOSE: To obtain the component effective as an antiallergic agent, by washing the bacterial cells obtained by the cultivation of lactic streptococci, suspending and disintegrating the cells in a liquid, separating and recovering the disintegrated cells, adding ethyl alcohol to the supernatant liquid, and separating the precipitated proteins.
CONSTITUTION: Bacterial cells obtained by the cultivation of lactic streptococci (e.g. Streptococcus lactis) are washed, dispersed in a liquid, and disintegrated. The liquid containing the disintegrated cells is separated, and the supernatant liquid of the separated liquid is recovered. The supernatant liquid is dialyzed with a semi-permeable membrane, and the residue is centrifuged to obtain its supernatant liquid containing the active component. Ethyl alcohol is added to the supernatant liquid to precipitate the proteins contained therein, and the precipitate is separated from the ethyl alcohol solution as a component effective as an antiallergic agent.
COPYRIGHT: (C)1982,JPO&Japio
JP56038790A 1980-05-12 1981-03-19 Antiallergic agent and its preparation Pending JPS57154132A (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP56038790A JPS57154132A (en) 1981-03-19 1981-03-19 Antiallergic agent and its preparation
GB8113273A GB2077101B (en) 1980-05-12 1981-04-29 Antiallergic composition containing streptococci
DE19813118148 DE3118148A1 (en) 1980-05-12 1981-05-07 Antiallergic product and process for its production
FR8109344A FR2481927A1 (en) 1980-05-12 1981-05-11 ANTI-ALLERGIC COMPOSITION AND PROCESS FOR THE PREPARATION THEREOF FROM A LACTIC ACID BACTERIUM OF THE GENUS STREPTOCOCCUS
AU78260/81A AU7826081A (en) 1981-03-19 1981-12-04 Antiallergic composition and process of preparation
ZA818531A ZA818531B (en) 1981-03-19 1981-12-09 Antiallergic composition and procress of preparing same
IT25578/81A IT1142095B (en) 1981-03-19 1981-12-14 ANTI-ALLERGIC COMPOSITION AND PROCEDURE TO PREPARE IT
NL8105655A NL8105655A (en) 1981-03-19 1981-12-15 ANTI-ALLERGIC PREPARATIONS AND METHODS FOR PREPARING THE SAME

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56038790A JPS57154132A (en) 1981-03-19 1981-03-19 Antiallergic agent and its preparation

Publications (1)

Publication Number Publication Date
JPS57154132A true JPS57154132A (en) 1982-09-22

Family

ID=12535095

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56038790A Pending JPS57154132A (en) 1980-05-12 1981-03-19 Antiallergic agent and its preparation

Country Status (5)

Country Link
JP (1) JPS57154132A (en)
AU (1) AU7826081A (en)
IT (1) IT1142095B (en)
NL (1) NL8105655A (en)
ZA (1) ZA818531B (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5946490A (en) * 1982-09-08 1984-03-15 Kobe Steel Ltd Heat transmitting tube for heat exchanger of boiling type

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5946490A (en) * 1982-09-08 1984-03-15 Kobe Steel Ltd Heat transmitting tube for heat exchanger of boiling type

Also Published As

Publication number Publication date
ZA818531B (en) 1982-11-24
NL8105655A (en) 1982-10-18
IT1142095B (en) 1986-10-08
AU7826081A (en) 1982-09-23
IT8125578A0 (en) 1981-12-14

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