JPS57122062A - Novel trans-4-guanidinocyclohexanecarboxylic acid derivative and its preparation - Google Patents
Novel trans-4-guanidinocyclohexanecarboxylic acid derivative and its preparationInfo
- Publication number
- JPS57122062A JPS57122062A JP728581A JP728581A JPS57122062A JP S57122062 A JPS57122062 A JP S57122062A JP 728581 A JP728581 A JP 728581A JP 728581 A JP728581 A JP 728581A JP S57122062 A JPS57122062 A JP S57122062A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- trans
- preparation
- acid derivative
- guanidinocyclohexanecarboxylic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- HKNFSQIYNOWVFO-IZLXSQMJSA-N NC(=N)N[C@H]1CC[C@H](C(O)=O)CC1 Chemical class NC(=N)N[C@H]1CC[C@H](C(O)=O)CC1 HKNFSQIYNOWVFO-IZLXSQMJSA-N 0.000 title abstract 2
- 108091005804 Peptidases Proteins 0.000 abstract 2
- 239000004365 Protease Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- DRNGLYHKYPNTEA-UHFFFAOYSA-N 4-azaniumylcyclohexane-1-carboxylate Chemical compound NC1CCC(C(O)=O)CC1 DRNGLYHKYPNTEA-UHFFFAOYSA-N 0.000 abstract 1
- 108090000317 Chymotrypsin Proteins 0.000 abstract 1
- 108060005987 Kallikrein Proteins 0.000 abstract 1
- 102000001399 Kallikrein Human genes 0.000 abstract 1
- 102000035195 Peptidases Human genes 0.000 abstract 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 abstract 1
- 108090000631 Trypsin Proteins 0.000 abstract 1
- 102000004142 Trypsin Human genes 0.000 abstract 1
- 102000003990 Urokinase-type plasminogen activator Human genes 0.000 abstract 1
- 108090000435 Urokinase-type plasminogen activator Proteins 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 229960002376 chymotrypsin Drugs 0.000 abstract 1
- 238000001816 cooling Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- -1 ester hydrochloride Chemical class 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 238000003756 stirring Methods 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
- 239000012588 trypsin Substances 0.000 abstract 1
- 229960005356 urokinase Drugs 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP728581A JPS57122062A (en) | 1981-01-22 | 1981-01-22 | Novel trans-4-guanidinocyclohexanecarboxylic acid derivative and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP728581A JPS57122062A (en) | 1981-01-22 | 1981-01-22 | Novel trans-4-guanidinocyclohexanecarboxylic acid derivative and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS57122062A true JPS57122062A (en) | 1982-07-29 |
| JPS642104B2 JPS642104B2 (enExample) | 1989-01-13 |
Family
ID=11661757
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP728581A Granted JPS57122062A (en) | 1981-01-22 | 1981-01-22 | Novel trans-4-guanidinocyclohexanecarboxylic acid derivative and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS57122062A (enExample) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0775692B1 (en) * | 1994-08-30 | 2000-12-06 | Teikoku Chemical Industry Co., Ltd. | Guanidinomethyl cyclohexane carboxylic ester derivative |
| US6444703B1 (en) | 1995-12-22 | 2002-09-03 | Teikoku Chemical Industries Co., Ltd. | Cyclohexane carbocyclic ester derivative and cyclodextrin complex and composition for treatment of helicobacter pylori infections |
| WO2003078381A1 (en) * | 2002-03-18 | 2003-09-25 | Tanabe Seiyaku Co., Ltd. | PROCESS FOR PREPARATION OF trans-4-AMINOCYCLOHEXANE- CARBOXYLIC ACIDS |
| WO2005000839A1 (ja) * | 2003-06-30 | 2005-01-06 | Tanabe Seiyaku Co., Ltd. | ３－アシルアミノベンゾフラン－２－カルボン酸誘導体の製法 |
| JP2005247824A (ja) * | 2003-06-30 | 2005-09-15 | Tanabe Seiyaku Co Ltd | ３−アシルアミノベンゾフラン−２−カルボン酸誘導体の製法 |
-
1981
- 1981-01-22 JP JP728581A patent/JPS57122062A/ja active Granted
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0775692B1 (en) * | 1994-08-30 | 2000-12-06 | Teikoku Chemical Industry Co., Ltd. | Guanidinomethyl cyclohexane carboxylic ester derivative |
| US6284791B1 (en) | 1994-08-30 | 2001-09-04 | Teikoku Chemical Industries Co., Ltd. | Guanidinomethyl cyclohexane carboxylic acid ester derivatives |
| US6831190B1 (en) | 1994-08-30 | 2004-12-14 | Teikoku Chemical Industries Co., Ltd. | Guanidinomethyl cyclohexane carboxylic acid ester derivatives |
| US6444703B1 (en) | 1995-12-22 | 2002-09-03 | Teikoku Chemical Industries Co., Ltd. | Cyclohexane carbocyclic ester derivative and cyclodextrin complex and composition for treatment of helicobacter pylori infections |
| WO2003078381A1 (en) * | 2002-03-18 | 2003-09-25 | Tanabe Seiyaku Co., Ltd. | PROCESS FOR PREPARATION OF trans-4-AMINOCYCLOHEXANE- CARBOXYLIC ACIDS |
| WO2005000839A1 (ja) * | 2003-06-30 | 2005-01-06 | Tanabe Seiyaku Co., Ltd. | ３－アシルアミノベンゾフラン－２－カルボン酸誘導体の製法 |
| JP2005247824A (ja) * | 2003-06-30 | 2005-09-15 | Tanabe Seiyaku Co Ltd | ３−アシルアミノベンゾフラン−２−カルボン酸誘導体の製法 |
| AU2004252025B2 (en) * | 2003-06-30 | 2007-08-30 | Mitsubishi Tanabe Pharma Corporation | Process for producing 3-acylaminobenzofuran-2-carboxylic acid derivative |
| KR100833837B1 (ko) * | 2003-06-30 | 2008-06-02 | 다나베 미츠비시 세이야꾸 가부시키가이샤 | 3-아실아미노벤조푸란-2-카르복실산 유도체의 제법 |
| US7439368B2 (en) | 2003-06-30 | 2008-10-21 | Mitsubishi Tanabe Pharma Corporation | Process for producing 3-acylaminobenzofuran-2-carboxylic acid derivative |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS642104B2 (enExample) | 1989-01-13 |
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