JPS5697277A - Thiazolidine derivative - Google Patents
Thiazolidine derivativeInfo
- Publication number
- JPS5697277A JPS5697277A JP76280A JP76280A JPS5697277A JP S5697277 A JPS5697277 A JP S5697277A JP 76280 A JP76280 A JP 76280A JP 76280 A JP76280 A JP 76280A JP S5697277 A JPS5697277 A JP S5697277A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- hydroxyl group
- derivative
- alkoxyl
- acyloxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/54—Nitrogen and either oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP76280A JPS5697277A (en) | 1980-01-07 | 1980-01-07 | Thiazolidine derivative |
AR283833A AR228444A1 (es) | 1980-01-07 | 1980-12-30 | Procedimiento para preparar derivados de 5-bencil-tiazolidin-2,4-diona y sus sales |
DK2281A DK2281A (da) | 1980-01-07 | 1981-01-05 | Fremgangsmaade til fremstilling af tiazolinderivater |
ES498320A ES498320A0 (es) | 1980-01-07 | 1981-01-05 | Metodo de producir derivados de tiazolidina |
US06/222,881 US4376777A (en) | 1980-01-07 | 1981-01-06 | Thiazolidine derivatives use |
EP81300027A EP0032128A1 (en) | 1980-01-07 | 1981-01-06 | Thiazolidine derivatives and their production and use |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP76280A JPS5697277A (en) | 1980-01-07 | 1980-01-07 | Thiazolidine derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5697277A true JPS5697277A (en) | 1981-08-05 |
JPS6310702B2 JPS6310702B2 (ja) | 1988-03-08 |
Family
ID=11482698
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP76280A Granted JPS5697277A (en) | 1980-01-07 | 1980-01-07 | Thiazolidine derivative |
Country Status (6)
Country | Link |
---|---|
US (1) | US4376777A (ja) |
EP (1) | EP0032128A1 (ja) |
JP (1) | JPS5697277A (ja) |
AR (1) | AR228444A1 (ja) |
DK (1) | DK2281A (ja) |
ES (1) | ES498320A0 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1986002073A1 (en) * | 1984-10-03 | 1986-04-10 | Takeda Chemical Industries, Ltd. | Thiazolidinedione derivatives, process for their preparation, and pharmaceutical composition containing same |
EP0211670A2 (en) * | 1985-08-09 | 1987-02-25 | Eli Lilly And Company | Di-t-butylphenol compounds |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58118577A (ja) * | 1982-01-07 | 1983-07-14 | Takeda Chem Ind Ltd | チアゾリジン誘導体 |
JPS58177983A (ja) * | 1982-04-13 | 1983-10-18 | Takeda Chem Ind Ltd | チアゾリジン誘導体 |
US4738972A (en) * | 1985-05-21 | 1988-04-19 | Pfizer Inc. | Hypoglycemic thiazolidinediones |
WO1986007056A1 (en) * | 1985-05-21 | 1986-12-04 | Pfizer Inc. | Hypoglycemic thiazolidinediones |
US5691367A (en) * | 1985-08-09 | 1997-11-25 | Eli Lilly And Company | Aryl-substituted rhodanine derivatives |
US5356917A (en) * | 1985-08-09 | 1994-10-18 | Eli Lilly And Company | Aryl-substituted rhodanine derivatives |
US5260445A (en) * | 1987-09-04 | 1993-11-09 | Beecham Group P.L.C. | 2,4-thiazolidinediones |
JPH01180102U (ja) * | 1988-06-02 | 1989-12-25 | ||
US5216002A (en) * | 1989-12-21 | 1993-06-01 | Eli Lilly And Company | Method of treating inflammatory bowel disease |
PL166269B1 (pl) * | 1990-04-27 | 1995-04-28 | Orion Yh Tyma Oy | Sposób wytwarzania nowych farmakologicznie aktywnych pochodnych katecholul PL PL PL PL PL |
JPH0463570U (ja) * | 1990-10-09 | 1992-05-29 | ||
US5158966A (en) * | 1991-02-22 | 1992-10-27 | The University Of Colorado Foundation, Inc. | Method of treating type i diabetes |
JPH066904A (ja) * | 1991-03-01 | 1994-01-14 | Hitachi Kiden Kogyo Ltd | クリーンルーム用無人搬送車の無人給電装置 |
IL106877A (en) * | 1992-09-10 | 1998-03-10 | Lilly Co Eli | Rodinin derivatives for use as drugs for the treatment of Alzheimer's disease |
USRE39384E1 (en) | 1993-09-01 | 2006-11-07 | Smithkline Beecham P.L.C. | Substituted thiazolidinedione derivatives |
US6251928B1 (en) | 1994-03-16 | 2001-06-26 | Eli Lilly And Company | Treatment of alzheimer's disease employing inhibitors of cathepsin D |
DE69838789T2 (de) * | 1997-03-12 | 2008-10-30 | Suzanne Cambridge de la Monte | Verfahren zur behandlung oder prävention der alzheimerischen krankheit |
ES2284212T3 (es) * | 1997-06-18 | 2007-11-01 | Smithkline Beecham Plc | Tratamiento de diabetes con tiazolidinadiona y metformina. |
KR20080011356A (ko) | 1997-06-18 | 2008-02-01 | 스미스클라인비이참피이엘시이 | 티아졸리딘디온 및 술포닐우레아를 사용한 당뇨병의 치료 |
GB9715306D0 (en) * | 1997-07-18 | 1997-09-24 | Smithkline Beecham Plc | Novel method of treatment |
GB9715295D0 (en) * | 1997-07-18 | 1997-09-24 | Smithkline Beecham Plc | Novel method of treatment |
US20040058873A1 (en) * | 1998-03-12 | 2004-03-25 | Esmond Robert W. | Method for treating or preventing Alzheimer's disease |
US7105552B2 (en) | 1998-05-08 | 2006-09-12 | Theracos, Inc. | Heterocyclic analogs of diphenylethylene compounds |
AR023699A1 (es) * | 1998-11-12 | 2002-09-04 | Smithkline Beecham Corp | Una composicion farmaceutica que comprende un estabilizador de insulina y un procedimiento para preparar una composicion farmaceutica |
GB9824893D0 (en) * | 1998-11-12 | 1999-01-06 | Smithkline Beckman Corp | Novel method of treatment |
EP1813273A1 (en) | 1998-11-12 | 2007-08-01 | Smithkline Beecham Plc | Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent |
US6191154B1 (en) | 1998-11-27 | 2001-02-20 | Case Western Reserve University | Compositions and methods for the treatment of Alzheimer's disease, central nervous system injury, and inflammatory diseases |
US7407978B2 (en) | 1999-04-06 | 2008-08-05 | Theracos, Inc. | Heterocyclic analogs of diphenylethylene compounds |
JP2001072592A (ja) | 1999-07-01 | 2001-03-21 | Kyowa Hakko Kogyo Co Ltd | テロメラーゼ阻害剤 |
JP2003507473A (ja) * | 1999-07-01 | 2003-02-25 | ジェロン コーポレイション | テロメラーゼインヒビターおよびその使用の方法 |
US6958355B2 (en) * | 2000-04-24 | 2005-10-25 | Aryx Therapeutics, Inc. | Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis |
US6680387B2 (en) * | 2000-04-24 | 2004-01-20 | Aryx Therapeutics | Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis |
US6768008B2 (en) | 2000-04-24 | 2004-07-27 | Aryx Therapeutics | Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis |
GB0014969D0 (en) | 2000-06-19 | 2000-08-09 | Smithkline Beecham Plc | Novel method of treatment |
WO2002024689A1 (en) | 2000-09-21 | 2002-03-28 | Aryx Therapeutics | Isoxazolidine compounds useful in the treatment of diabetes, hyperlipidemia, and atherosclerosis |
US6452014B1 (en) | 2000-12-22 | 2002-09-17 | Geron Corporation | Telomerase inhibitors and methods of their use |
US20060047000A1 (en) * | 2001-04-24 | 2006-03-02 | Aryx Therapeutics, Inc. | Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis |
KR100849288B1 (ko) * | 2002-01-16 | 2008-07-29 | 제너럴 일렉트릭 캄파니 | 자동차 계기 패널 조립체용 중앙 스택과, 계기 패널용중앙 스택 제조 방법 및 자동차 계기 패널 중앙 스택 키트 |
US8268352B2 (en) * | 2002-08-05 | 2012-09-18 | Torrent Pharmaceuticals Limited | Modified release composition for highly soluble drugs |
US8216609B2 (en) * | 2002-08-05 | 2012-07-10 | Torrent Pharmaceuticals Limited | Modified release composition of highly soluble drugs |
EP1563211A1 (en) * | 2002-11-21 | 2005-08-17 | Delavan Limited | Check valve |
WO2005041951A2 (en) * | 2003-10-28 | 2005-05-12 | Rigel Pharmaceuticals, Inc. | Rhodanine derivatives for use as antiviral agents |
AR057324A1 (es) * | 2005-05-27 | 2007-11-28 | Wyeth Corp | Tigeciclina y metodos para preparar 9-aminominociclina |
EP2254576B1 (en) * | 2008-02-22 | 2013-08-28 | The Ohio State University Research Foundation | Androgen receptor-ablative agents |
JP5847085B2 (ja) | 2009-10-09 | 2016-01-20 | ザ オハイオ ステート ユニバーシティー リサーチ ファウンデーション | チアゾリジンジオンエネルギー制限模倣剤 |
US20120094959A1 (en) | 2010-10-19 | 2012-04-19 | Bonnie Blazer-Yost | Treatment of cystic diseases |
WO2016071727A1 (en) | 2014-11-04 | 2016-05-12 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for the prevention and the treatment of rapidly progressive glomerulonephritis |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1284516A (fr) * | 1957-11-20 | 1962-02-16 | France Etat | Produits utilisables notamment comme agents susceptibles d'agir sur la croissance des plantes et leur procédé de fabrication |
NL125835C (ja) * | 1960-05-24 | |||
US3200126A (en) * | 1963-05-31 | 1965-08-10 | Warner Lambert Pharmaceutical | 3-alkyl-5-amino-2, 4-thiazolidinediones |
US3825553A (en) * | 1970-05-05 | 1974-07-23 | Rorer Inc William H | Certain 5-arylthiazolidines |
SU480711A1 (ru) * | 1973-07-02 | 1975-08-15 | Ленинградский Ордена Трудового Красного Знамени Технологический Институт Им.Ленсовета | Способ получени производных 3-оксиметилтиазолиндиона-2,4 |
JPS5522636A (en) * | 1978-08-04 | 1980-02-18 | Takeda Chem Ind Ltd | Thiazoliding derivative |
-
1980
- 1980-01-07 JP JP76280A patent/JPS5697277A/ja active Granted
- 1980-12-30 AR AR283833A patent/AR228444A1/es active
-
1981
- 1981-01-05 DK DK2281A patent/DK2281A/da unknown
- 1981-01-05 ES ES498320A patent/ES498320A0/es active Granted
- 1981-01-06 EP EP81300027A patent/EP0032128A1/en not_active Withdrawn
- 1981-01-06 US US06/222,881 patent/US4376777A/en not_active Expired - Fee Related
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1986002073A1 (en) * | 1984-10-03 | 1986-04-10 | Takeda Chemical Industries, Ltd. | Thiazolidinedione derivatives, process for their preparation, and pharmaceutical composition containing same |
EP0211670A2 (en) * | 1985-08-09 | 1987-02-25 | Eli Lilly And Company | Di-t-butylphenol compounds |
Also Published As
Publication number | Publication date |
---|---|
JPS6310702B2 (ja) | 1988-03-08 |
DK2281A (da) | 1981-07-08 |
AR228444A1 (es) | 1983-03-15 |
ES8202546A1 (es) | 1982-02-01 |
US4376777A (en) | 1983-03-15 |
ES498320A0 (es) | 1982-02-01 |
EP0032128A1 (en) | 1981-07-15 |
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