JPS5692899A - Composition containing s-adenosyl-l-methionine, and its preparation - Google Patents

Composition containing s-adenosyl-l-methionine, and its preparation

Info

Publication number
JPS5692899A
JPS5692899A JP15729579A JP15729579A JPS5692899A JP S5692899 A JPS5692899 A JP S5692899A JP 15729579 A JP15729579 A JP 15729579A JP 15729579 A JP15729579 A JP 15729579A JP S5692899 A JPS5692899 A JP S5692899A
Authority
JP
Japan
Prior art keywords
adenosyl
methionine
aqueous solvent
magnesium sulfate
remedy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP15729579A
Other languages
Japanese (ja)
Other versions
JPS634555B2 (en
Inventor
Hajime Kawarada
Yuichi Kamisaki
Shingo Hata
Kiyoshi Watanabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kanegafuchi Chemical Industry Co Ltd
Original Assignee
Kanegafuchi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kanegafuchi Chemical Industry Co Ltd filed Critical Kanegafuchi Chemical Industry Co Ltd
Priority to JP15729579A priority Critical patent/JPS5692899A/en
Priority to GB8036501A priority patent/GB2064523B/en
Priority to US06/208,842 priority patent/US4369177A/en
Priority to CA000365349A priority patent/CA1158556A/en
Priority to FR8025464A priority patent/FR2471188A1/en
Priority to IT50287/80A priority patent/IT1188968B/en
Priority to ES497403A priority patent/ES497403A0/en
Priority to DE19803045786 priority patent/DE3045786A1/en
Publication of JPS5692899A publication Critical patent/JPS5692899A/en
Publication of JPS634555B2 publication Critical patent/JPS634555B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

PURPOSE: To improve the storage stability and in vivostability of S-adenosyl-L- methionine useful as a remedy for hypometabolic diseases, and to obtain the titled composition, economically, in an industrial scale, by adding sulfate radical and magnesium sulfate to the compound.
CONSTITUTION: S-adenosyl-L-methionine, sulfate radical (other than those originated from magnesium sulfate, e.g. sulfuric acid), and magnesium sulfate are dissolved in an aqueous solvent pref. at concentrations of 3W10(W/V)%, 1W25%, and 0.3W50%, respectively. The objective composition is prepared by evaporating the aqueous solvent to dryness, or by contacting the aqueous solvent with an organic solvent (e.g. methanol, methyl ethyl ketone, etc.).
USE: Remedy for jecur adiposum, hyperlipemia, arteriosclerosis, depression, degenerative arthrosis, neuropathic algesthesia, insomnia, etc.
COPYRIGHT: (C)1981,JPO&Japio
JP15729579A 1979-12-04 1979-12-04 Composition containing s-adenosyl-l-methionine, and its preparation Granted JPS5692899A (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP15729579A JPS5692899A (en) 1979-12-04 1979-12-04 Composition containing s-adenosyl-l-methionine, and its preparation
GB8036501A GB2064523B (en) 1979-12-04 1980-11-13 Stable composition of s-adenosyl-l-methionine
US06/208,842 US4369177A (en) 1979-12-04 1980-11-20 Stable composition of S-adenosyl-L-methionine
CA000365349A CA1158556A (en) 1979-12-04 1980-11-24 Stable composition of s-adenosyle-l-methionine
FR8025464A FR2471188A1 (en) 1979-12-04 1980-12-01 STABLE COMPOSITION OF S-ADENOSYL-L-METHIONINE AND PROCESS FOR PREPARING SAME
IT50287/80A IT1188968B (en) 1979-12-04 1980-12-02 STABLE COMPOSITION OF S-ADENOSILL-METHIONINE AND PROCEDURE TO PREPARE IT
ES497403A ES497403A0 (en) 1979-12-04 1980-12-03 PROCEDURE FOR PREPARING A STABLE COMPOSITION OF S-ADENOSYL-L-METHIONINE
DE19803045786 DE3045786A1 (en) 1979-12-04 1980-12-04 STABLE S-ADENOSYL-L-METHIONINE FORMULATION AND METHOD FOR THE PRODUCTION THEREOF

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15729579A JPS5692899A (en) 1979-12-04 1979-12-04 Composition containing s-adenosyl-l-methionine, and its preparation

Publications (2)

Publication Number Publication Date
JPS5692899A true JPS5692899A (en) 1981-07-27
JPS634555B2 JPS634555B2 (en) 1988-01-29

Family

ID=15646532

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15729579A Granted JPS5692899A (en) 1979-12-04 1979-12-04 Composition containing s-adenosyl-l-methionine, and its preparation

Country Status (1)

Country Link
JP (1) JPS5692899A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59109190A (en) * 1982-12-14 1984-06-23 Nippon Zeon Co Ltd Extractive separation of s-adenosyl-l-methionine
JPS6191125A (en) * 1984-10-11 1986-05-09 Nippon Zeon Co Ltd Composition containing s-adenosyl-l-methionine, and its production
KR20140079389A (en) * 2011-10-06 2014-06-26 라이온 가부시키가이샤 Agent for improving quality of sleep

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59109190A (en) * 1982-12-14 1984-06-23 Nippon Zeon Co Ltd Extractive separation of s-adenosyl-l-methionine
JPH0335917B2 (en) * 1982-12-14 1991-05-29 Nippon Zeon Co
JPS6191125A (en) * 1984-10-11 1986-05-09 Nippon Zeon Co Ltd Composition containing s-adenosyl-l-methionine, and its production
JPH0546360B2 (en) * 1984-10-11 1993-07-13 Nippon Zeon Co
KR20140079389A (en) * 2011-10-06 2014-06-26 라이온 가부시키가이샤 Agent for improving quality of sleep

Also Published As

Publication number Publication date
JPS634555B2 (en) 1988-01-29

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