JPS5679654A - Preparation of 2-anilinophenylacetic acid ester - Google Patents
Preparation of 2-anilinophenylacetic acid esterInfo
- Publication number
- JPS5679654A JPS5679654A JP15425279A JP15425279A JPS5679654A JP S5679654 A JPS5679654 A JP S5679654A JP 15425279 A JP15425279 A JP 15425279A JP 15425279 A JP15425279 A JP 15425279A JP S5679654 A JPS5679654 A JP S5679654A
- Authority
- JP
- Japan
- Prior art keywords
- acid ester
- formula
- preparation
- anilinophenylacetic
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: To prepare the titled compound useful as an antiphlogistic agent and its synthetic intermediate, economically, by halogenating a novel iminocyclohexane-2- acetic acid ester, and then dehydrohalogenating the product.
CONSTITUTION: A novel compound of formula I (R is alkyl) is halogenated e.g. with N-chlorosuccinimide, etc. pref. in a solvent such as CCl4 at -30W+90°C. The reaction product is dehydrohalogenated with a basic substance or a Lewis acid, etc. to obtain a 2-anilinophenylacetic acid ester of formula II. The compound of formula I is prepared by converting e.g. a cyclohexanone-2-acetic acid ester to a lower alkyl acetal, and then heating with 2,6-dichloroaniline.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15425279A JPS5679654A (en) | 1979-11-30 | 1979-11-30 | Preparation of 2-anilinophenylacetic acid ester |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15425279A JPS5679654A (en) | 1979-11-30 | 1979-11-30 | Preparation of 2-anilinophenylacetic acid ester |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5679654A true JPS5679654A (en) | 1981-06-30 |
Family
ID=15580148
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP15425279A Pending JPS5679654A (en) | 1979-11-30 | 1979-11-30 | Preparation of 2-anilinophenylacetic acid ester |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5679654A (en) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5520727A (en) * | 1978-08-02 | 1980-02-14 | Mitsui Toatsu Chem Inc | Preparation of 2-anilinophenyl acetate |
-
1979
- 1979-11-30 JP JP15425279A patent/JPS5679654A/en active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5520727A (en) * | 1978-08-02 | 1980-02-14 | Mitsui Toatsu Chem Inc | Preparation of 2-anilinophenyl acetate |
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