JPS5520727A - Preparation of 2-anilinophenyl acetate - Google Patents
Preparation of 2-anilinophenyl acetateInfo
- Publication number
- JPS5520727A JPS5520727A JP9368078A JP9368078A JPS5520727A JP S5520727 A JPS5520727 A JP S5520727A JP 9368078 A JP9368078 A JP 9368078A JP 9368078 A JP9368078 A JP 9368078A JP S5520727 A JPS5520727 A JP S5520727A
- Authority
- JP
- Japan
- Prior art keywords
- acetate
- formula
- compound shown
- anilinophenyl
- prepare
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: The prepare the title compound for use as an anti-inflammatory agent or its intermediate industrially and economically advantageously, by halogenating novel N-(2,6-dichlorophenyl)iminocyclohexane-2-acetate, followed by dehydrohalogenation.
CONSTITUTION: A novel compound shown by the formula I (R is alkyl) is halogenated by N-chlorosuccinic acid imide in an amount not too much excess of stoichiometric quantity. The product obtained is reacted with a dehydrohalogenating agent, e.g., pyridine, quinoline, having a relatively high boiling point preferably without purification to give the desired compound shown by the formula II. This compound is hydrolyzed to prepare 2-anilinophenyl acetate which is useful as an anodyne or an antifebrile. The compound shown by the formula I is obtained by changing cyclohexanone-2-acetate into its lower alkyl acetatal, which is heated with 2,6-dichloroaniline.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9368078A JPS5520727A (en) | 1978-08-02 | 1978-08-02 | Preparation of 2-anilinophenyl acetate |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9368078A JPS5520727A (en) | 1978-08-02 | 1978-08-02 | Preparation of 2-anilinophenyl acetate |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5520727A true JPS5520727A (en) | 1980-02-14 |
JPS6256862B2 JPS6256862B2 (en) | 1987-11-27 |
Family
ID=14089113
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP9368078A Granted JPS5520727A (en) | 1978-08-02 | 1978-08-02 | Preparation of 2-anilinophenyl acetate |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5520727A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5679654A (en) * | 1979-11-30 | 1981-06-30 | Mitsui Toatsu Chem Inc | Preparation of 2-anilinophenylacetic acid ester |
JPH04501745A (en) * | 1988-11-17 | 1992-03-26 | シユンドス・デフイブラトール・インダストリーズ・アクテイエボラーグ | Device for sieving pulp suspension |
-
1978
- 1978-08-02 JP JP9368078A patent/JPS5520727A/en active Granted
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5679654A (en) * | 1979-11-30 | 1981-06-30 | Mitsui Toatsu Chem Inc | Preparation of 2-anilinophenylacetic acid ester |
JPH04501745A (en) * | 1988-11-17 | 1992-03-26 | シユンドス・デフイブラトール・インダストリーズ・アクテイエボラーグ | Device for sieving pulp suspension |
Also Published As
Publication number | Publication date |
---|---|
JPS6256862B2 (en) | 1987-11-27 |
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