JPS5683487A

JPS5683487A - 2,5-di-substituted-1,3-dioxane derivative

2,5-di-substituted-1,3-dioxane derivative

Info

Publication number: JPS5683487A
Authority: JP; Japan
Prior art keywords: formula; compound; substituted; blood; dioxane
Prior art date: 1979-12-10
Legal status : Granted

Application number

JP16010079A

Other languages

English (en)

Japanese (ja)

Other versions

JPS638948B2 (enrdf_load_stackoverflow

Inventor

Tosaku Miki

Toshiyuki Yoshioka

Akira Eriguchi

Tamotsu Miwa

Kazufumi Abiko

Katsuhiko Tawara

Kyuichiro Takahashi

Current Assignee

Daiichi Pharmaceutical Co Ltd

Original Assignee

Daiichi Pharmaceutical Co Ltd

Priority date

1979-12-10

Filing date

1979-12-10

Publication date

1981-07-08

1979-12-10 Application filed by Daiichi Pharmaceutical Co Ltd filed Critical Daiichi Pharmaceutical Co Ltd

1979-12-10 Priority to JP16010079A priority Critical patent/JPS5683487A/ja

1981-07-08 Publication of JPS5683487A publication Critical patent/JPS5683487A/ja

1988-02-25 Publication of JPS638948B2 publication Critical patent/JPS638948B2/ja

Status Granted legal-status Critical Current

Links

-1 2,5-di-substituted-1,3-dioxane Chemical class 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 2
210000004369 blood Anatomy 0.000 abstract 2
239000008280 blood Substances 0.000 abstract 2
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
125000001622 2-naphthyl group Chemical group [H]C1=C([H])C([H])=C2C([H])=C(*)C([H])=C([H])C2=C1[H] 0.000 abstract 1
JAPBLZDUOKDZER-LBZQVFOQSA-N C1([C@H]2OC[C@@H](CO2)CC=2C=CC(OC=3C=CC=CC=3)=CC=2)=CC=CN=C1 Chemical compound C1([C@H]2OC[C@@H](CO2)CC=2C=CC(OC=3C=CC=CC=3)=CC=2)=CC=CN=C1 JAPBLZDUOKDZER-LBZQVFOQSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
239000003377 acid catalyst Substances 0.000 abstract 1
125000002947 alkylene group Chemical group 0.000 abstract 1
239000003524 antilipemic agent Substances 0.000 abstract 1
210000001772 blood platelet Anatomy 0.000 abstract 1
235000012000 cholesterol Nutrition 0.000 abstract 1
230000015271 coagulation Effects 0.000 abstract 1
238000005345 coagulation Methods 0.000 abstract 1
150000002012 dioxanes Chemical class 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
239000000463 material Substances 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
125000000714 pyrimidinyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
210000002966 serum Anatomy 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1
LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
231100000331 toxic Toxicity 0.000 abstract 1
230000002588 toxic effect Effects 0.000 abstract 1
UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 abstract 1