JPS567748A - Preparation of benzamide - Google Patents

Preparation of benzamide

Info

Publication number
JPS567748A
JPS567748A JP8269579A JP8269579A JPS567748A JP S567748 A JPS567748 A JP S567748A JP 8269579 A JP8269579 A JP 8269579A JP 8269579 A JP8269579 A JP 8269579A JP S567748 A JPS567748 A JP S567748A
Authority
JP
Japan
Prior art keywords
benzamide
hypohalogenite
halo
alkoxy
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8269579A
Other languages
Japanese (ja)
Inventor
Norio Akimoto
Hiroyuki Yamane
Tetsuo Saito
Shigeru Iwakiri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Chemical Industry Co Ltd
Original Assignee
Asahi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Chemical Industry Co Ltd filed Critical Asahi Chemical Industry Co Ltd
Priority to JP8269579A priority Critical patent/JPS567748A/en
Publication of JPS567748A publication Critical patent/JPS567748A/en
Pending legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: To prepare a benzamide useful as a neuroleptic agent, an antiemetic agent, a preventive for naupathia, etc., easily, in high yield, by reacting the corresponding benzdiamide with a hypohalogenite.
CONSTITUTION: A 2-alkoxy-5-halo-1-N-( tertiary aminoalkyl )-4-benzdicarboxylic amide of formula I (A, R1 and R2 are alkyl; W is alkylene; X is halogen) is reacted with a hypohalogenite to obtain the 2-alkoxy-4-amino-5-halo-1-N-(tertiary aminoalkyl)benzamide of formula II. The conversion of the 4-position acid amide to amine is carried out by using an aqueous solution of a hypohalogenite, e.g. a hypochlorite, preferably first at -5W0°C and then at 40W80°C.
COPYRIGHT: (C)1981,JPO&Japio
JP8269579A 1979-07-02 1979-07-02 Preparation of benzamide Pending JPS567748A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP8269579A JPS567748A (en) 1979-07-02 1979-07-02 Preparation of benzamide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8269579A JPS567748A (en) 1979-07-02 1979-07-02 Preparation of benzamide

Publications (1)

Publication Number Publication Date
JPS567748A true JPS567748A (en) 1981-01-27

Family

ID=13781540

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8269579A Pending JPS567748A (en) 1979-07-02 1979-07-02 Preparation of benzamide

Country Status (1)

Country Link
JP (1) JPS567748A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0262316A2 (en) * 1986-08-28 1988-04-06 ERPE - Ernst Pelz - Vertriebs GmbH + Co. - Verwaltungs KG Method for producing a lining element and lining element thus produced

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0262316A2 (en) * 1986-08-28 1988-04-06 ERPE - Ernst Pelz - Vertriebs GmbH + Co. - Verwaltungs KG Method for producing a lining element and lining element thus produced

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