JPS56127365A - Preparation of 5-chloro-2-benzothiazolinone derivative - Google Patents

Preparation of 5-chloro-2-benzothiazolinone derivative

Info

Publication number
JPS56127365A
JPS56127365A JP3058180A JP3058180A JPS56127365A JP S56127365 A JPS56127365 A JP S56127365A JP 3058180 A JP3058180 A JP 3058180A JP 3058180 A JP3058180 A JP 3058180A JP S56127365 A JPS56127365 A JP S56127365A
Authority
JP
Japan
Prior art keywords
chloro
benzothiazolinone
acetylpiperazine
hydroxyethyl
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP3058180A
Other languages
Japanese (ja)
Inventor
Seiichi Kitamura
Tomoya Ogawa
Narihiro Owaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aska Pharmaceutical Co Ltd
Teikoku Chemical Industry Co Ltd
RIKEN Institute of Physical and Chemical Research
Original Assignee
Teikoku Chemical Industry Co Ltd
Teikoku Hormone Manufacturing Co Ltd
RIKEN Institute of Physical and Chemical Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teikoku Chemical Industry Co Ltd, Teikoku Hormone Manufacturing Co Ltd, RIKEN Institute of Physical and Chemical Research filed Critical Teikoku Chemical Industry Co Ltd
Priority to JP3058180A priority Critical patent/JPS56127365A/en
Publication of JPS56127365A publication Critical patent/JPS56127365A/en
Pending legal-status Critical Current

Links

Abstract

PURPOSE: To obtain the titled compound which is an analgesic and an anit-inflammatory agents, etc. in high purity and high yield, by reacting a novel 5-chloro- 2-trialkylstannyloxybenzothiazole with an N-hydroxyethyl-N'-substituted acetylpiperazine.
CONSTITUTION: 5-Chloro-2-benzothiazolinone is reacted with an N-hydroxyethyl- N'-substituted acetylpiperazine to give a 5-chloro-2-benzothiazolinone derivative. In the process, a novel 5-chloro-2-trialkylstannyloxybenzothiazole obtained by reacting 5-chloro-2-benzothiazolinone with a trialkyltin compound, e.g. bis(tri-ethyltin) oxide or bis(tri-propyltin)oxide, is reacted with an N-hydroxyethyl-N'-substituted acetylpiperazine.
COPYRIGHT: (C)1981,JPO&Japio
JP3058180A 1980-03-10 1980-03-10 Preparation of 5-chloro-2-benzothiazolinone derivative Pending JPS56127365A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP3058180A JPS56127365A (en) 1980-03-10 1980-03-10 Preparation of 5-chloro-2-benzothiazolinone derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3058180A JPS56127365A (en) 1980-03-10 1980-03-10 Preparation of 5-chloro-2-benzothiazolinone derivative

Publications (1)

Publication Number Publication Date
JPS56127365A true JPS56127365A (en) 1981-10-06

Family

ID=12307809

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3058180A Pending JPS56127365A (en) 1980-03-10 1980-03-10 Preparation of 5-chloro-2-benzothiazolinone derivative

Country Status (1)

Country Link
JP (1) JPS56127365A (en)

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