JPS565488A - Isothiazolobenzisothiazolium salt and its preparation - Google Patents
Isothiazolobenzisothiazolium salt and its preparationInfo
- Publication number
- JPS565488A JPS565488A JP7942079A JP7942079A JPS565488A JP S565488 A JPS565488 A JP S565488A JP 7942079 A JP7942079 A JP 7942079A JP 7942079 A JP7942079 A JP 7942079A JP S565488 A JPS565488 A JP S565488A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- acid
- benzothiazocine
- lower alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:The titled compound of formula I (R1 and R2 are H or lower alkyl groups; X1 and X2 are H, lower alkyl, lower alkoxy groups, etc.; Y is acid residue).
EXAMPLE: 2, 3-Dihydro-7-methyl-1H, 5H-isothiazolo[ 2, 1-a ][ 2, 1 ]benzoisothiazolium chloride.
USE: A drug for peptic ulcer having a gastric secretion suppressing action and an intermediate for the synthesis of a benzothiazocine-S-oxide compound having the powerful action.
PROCESS: A benzothiazocine-S-oxide compound of formula II is reacted with an acid, e.g. a mineral acid such as hydrochloric, nitric or sulfuric acid, in a solvent, e.g. methanol, at room temperature for 5minW1hr to give the compound of formula I. The resulting compound can be converted into the compound of formula II by treating with a base, e.g. NaOH or KOH.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7942079A JPS565488A (en) | 1979-06-23 | 1979-06-23 | Isothiazolobenzisothiazolium salt and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7942079A JPS565488A (en) | 1979-06-23 | 1979-06-23 | Isothiazolobenzisothiazolium salt and its preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS565488A true JPS565488A (en) | 1981-01-20 |
Family
ID=13689364
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP7942079A Pending JPS565488A (en) | 1979-06-23 | 1979-06-23 | Isothiazolobenzisothiazolium salt and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS565488A (en) |
-
1979
- 1979-06-23 JP JP7942079A patent/JPS565488A/en active Pending
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