JPS565466A - Preparation of 5-methylpyrimidine derivative - Google Patents

Preparation of 5-methylpyrimidine derivative

Info

Publication number
JPS565466A
JPS565466A JP7913679A JP7913679A JPS565466A JP S565466 A JPS565466 A JP S565466A JP 7913679 A JP7913679 A JP 7913679A JP 7913679 A JP7913679 A JP 7913679A JP S565466 A JPS565466 A JP S565466A
Authority
JP
Japan
Prior art keywords
derivative
acid
formula
metal
hydroxymethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP7913679A
Other languages
Japanese (ja)
Other versions
JPS6152828B2 (en
Inventor
Shinji Sakata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamasa Shoyu KK
Original Assignee
Yamasa Shoyu KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamasa Shoyu KK filed Critical Yamasa Shoyu KK
Priority to JP7913679A priority Critical patent/JPS565466A/en
Publication of JPS565466A publication Critical patent/JPS565466A/en
Publication of JPS6152828B2 publication Critical patent/JPS6152828B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Saccharide Compounds (AREA)

Abstract

PURPOSE: To prepare economically the titled compound to be anticipated as a drug, having an action of lowering side effect of an antitumor agent, etc., by reacting a 5-hydroxy-methylpyrimidine derivative with a metal such as zinc in the presence of a hydrohalogenic acid.
CONSTITUTION: A 5-hydroxymethylpyrimidine derivative (e.g., 5-hydroxymethyl- 2',3-O-isopropylideneuridine) shown by the formula I (R is pentose which may have a protecting group, pentose phosphate, or H) is reacted with a metal in the presence of a hydrohagenic acid (e.g., hydriodic acid, etc.) so that a hydroxymethyl group at 5-position is reduced to methyl group to give the desired compound shown by the formula II (e.g., 5-methyluridine).
EFFECT: A high-priced catalyst and a device for catalytic reduction are not required in use.
COPYRIGHT: (C)1981,JPO&Japio
JP7913679A 1979-06-25 1979-06-25 Preparation of 5-methylpyrimidine derivative Granted JPS565466A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP7913679A JPS565466A (en) 1979-06-25 1979-06-25 Preparation of 5-methylpyrimidine derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7913679A JPS565466A (en) 1979-06-25 1979-06-25 Preparation of 5-methylpyrimidine derivative

Publications (2)

Publication Number Publication Date
JPS565466A true JPS565466A (en) 1981-01-20
JPS6152828B2 JPS6152828B2 (en) 1986-11-14

Family

ID=13681530

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7913679A Granted JPS565466A (en) 1979-06-25 1979-06-25 Preparation of 5-methylpyrimidine derivative

Country Status (1)

Country Link
JP (1) JPS565466A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60101121A (en) * 1983-10-12 1985-06-05 チバ‐ガイギー　アクチエンゲゼルシヤフト Radiation-reactive polycondensate, manufacture, coated material and use

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60101121A (en) * 1983-10-12 1985-06-05 チバ‐ガイギー　アクチエンゲゼルシヤフト Radiation-reactive polycondensate, manufacture, coated material and use

Also Published As

Publication number Publication date
JPS6152828B2 (en) 1986-11-14

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