JPS5649384A - Beta-lactam derivative - Google Patents
Beta-lactam derivativeInfo
- Publication number
- JPS5649384A JPS5649384A JP12471379A JP12471379A JPS5649384A JP S5649384 A JPS5649384 A JP S5649384A JP 12471379 A JP12471379 A JP 12471379A JP 12471379 A JP12471379 A JP 12471379A JP S5649384 A JPS5649384 A JP S5649384A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- benzyl
- beta
- base
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A compound of formula I (Y is OH, lower alkoxy, lower alkanoyloxy, etc.; R2 is H or benzyl) and its salt.
EXAMPLE: 3-( 2-Hydroxyethylthio )-6-ethyl-7-oxo-1-azabicyclo[ 3,2,0 ] hept-2-ene-2- carboxylic acid p-nitrobenzyl ester.
USE: An antibacterial agent.
PROCESS: The compound of formula I is prepared by reacting a compound of formula (R2' is benzyl) with a thiol compound of formula Y-CH2-CH2-SH, if necessary in the presence of a base (e.g. NaH, NaOH, etc.) in a solvent such as N,N-dimethylformamide, etc. at a low temperature (≤-20°C, pref. -30W-50°C). In the above reaction, a reactive derivative of the thiol compound (e.g. sodium ethanetholate) may be used in place of the base.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12471379A JPS5649384A (en) | 1979-09-29 | 1979-09-29 | Beta-lactam derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12471379A JPS5649384A (en) | 1979-09-29 | 1979-09-29 | Beta-lactam derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5649384A true JPS5649384A (en) | 1981-05-02 |
JPS6345392B2 JPS6345392B2 (en) | 1988-09-09 |
Family
ID=14892257
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP12471379A Granted JPS5649384A (en) | 1979-09-29 | 1979-09-29 | Beta-lactam derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5649384A (en) |
-
1979
- 1979-09-29 JP JP12471379A patent/JPS5649384A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS6345392B2 (en) | 1988-09-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU7949291A (en) | Process for the preparation of an n-phenylacetic derivative of tetrahydrothieno(3,2-c)pyridine and its chemical intermediate | |
JPS57142962A (en) | Cyclodextrin clathrate compound of sulfur-containing compound | |
JPS5649384A (en) | Beta-lactam derivative | |
JPS5746988A (en) | Novel penicillin derivative and its preparation | |
JPS55147284A (en) | Novel beta-lactam derivative and its preparation | |
JPS5466695A (en) | Azetidinone derivative and its preparation | |
JPS5649383A (en) | Beta-lactam compound | |
JPS5754177A (en) | Substituted thiazole derivative | |
JPS5616489A (en) | Imidazolecarboxylic acid derivative | |
JPS5515454A (en) | Novel cephalosporin derivative | |
JPS5655383A (en) | Amizine derivative and its preparation | |
JPS5562082A (en) | Tetrahydroxanthone derivative | |
JPS572278A (en) | Dibenzoxazepin derivative | |
JPS54128599A (en) | Pyrrolobenzazepin derivative | |
JPS5798258A (en) | Beta-lactamase inhibitor composition | |
JPS57144254A (en) | 2-substituted-2-oxoazetidine derivative and its preparation | |
JPS55120591A (en) | Phosphinoethylmalonic acid derivative, and preparation thereof | |
JPS5566594A (en) | Preparation of cephalosporin analog | |
JPS5711975A (en) | Aminophenyltetrazole derivative and salt thereof | |
JPS5726658A (en) | 4r -4- 3-substituted carboxy-3-diazo-2-oxopropyl -2- azetidinone derivative and its preparation | |
JPS54135791A (en) | 7-methoxycephalosporin compound, its preparation, and antibacterial agent containing the compound as main component | |
JPS57165376A (en) | Novel 2-benzothiazolinone derivative and its preparation | |
JPS57169489A (en) | Cephalosporin derivative and its preparation | |
JPS5598188A (en) | Novel cephalosporin and its preparation | |
JPS5618971A (en) | Alpha-halogeno-beta-benzosulfimidopropionitrile and its preparation |