JPS5649384A - Beta-lactam derivative - Google Patents

Beta-lactam derivative

Info

Publication number
JPS5649384A
JPS5649384A JP12471379A JP12471379A JPS5649384A JP S5649384 A JPS5649384 A JP S5649384A JP 12471379 A JP12471379 A JP 12471379A JP 12471379 A JP12471379 A JP 12471379A JP S5649384 A JPS5649384 A JP S5649384A
Authority
JP
Japan
Prior art keywords
formula
compound
benzyl
beta
base
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP12471379A
Other languages
Japanese (ja)
Other versions
JPS6345392B2 (en
Inventor
Takeo Yoshioka
Kenichi Yamamoto
Kaoru Yamada
Yasuyuki Kato
Yasutaka Shimauchi
Tomoyuki Ishikura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanraku Inc
Sanraku Ocean Co Ltd
Original Assignee
Sanraku Inc
Sanraku Ocean Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanraku Inc, Sanraku Ocean Co Ltd filed Critical Sanraku Inc
Priority to JP12471379A priority Critical patent/JPS5649384A/en
Publication of JPS5649384A publication Critical patent/JPS5649384A/en
Publication of JPS6345392B2 publication Critical patent/JPS6345392B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A compound of formula I (Y is OH, lower alkoxy, lower alkanoyloxy, etc.; R2 is H or benzyl) and its salt.
EXAMPLE: 3-( 2-Hydroxyethylthio )-6-ethyl-7-oxo-1-azabicyclo[ 3,2,0 ] hept-2-ene-2- carboxylic acid p-nitrobenzyl ester.
USE: An antibacterial agent.
PROCESS: The compound of formula I is prepared by reacting a compound of formula (R2' is benzyl) with a thiol compound of formula Y-CH2-CH2-SH, if necessary in the presence of a base (e.g. NaH, NaOH, etc.) in a solvent such as N,N-dimethylformamide, etc. at a low temperature (≤-20°C, pref. -30W-50°C). In the above reaction, a reactive derivative of the thiol compound (e.g. sodium ethanetholate) may be used in place of the base.
COPYRIGHT: (C)1981,JPO&Japio
JP12471379A 1979-09-29 1979-09-29 Beta-lactam derivative Granted JPS5649384A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12471379A JPS5649384A (en) 1979-09-29 1979-09-29 Beta-lactam derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12471379A JPS5649384A (en) 1979-09-29 1979-09-29 Beta-lactam derivative

Publications (2)

Publication Number Publication Date
JPS5649384A true JPS5649384A (en) 1981-05-02
JPS6345392B2 JPS6345392B2 (en) 1988-09-09

Family

ID=14892257

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12471379A Granted JPS5649384A (en) 1979-09-29 1979-09-29 Beta-lactam derivative

Country Status (1)

Country Link
JP (1) JPS5649384A (en)

Also Published As

Publication number Publication date
JPS6345392B2 (en) 1988-09-09

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