JPS5649378A - Tetrazolylalkoxycarbostyril derivative - Google Patents
Tetrazolylalkoxycarbostyril derivativeInfo
- Publication number
- JPS5649378A JPS5649378A JP10838979A JP10838979A JPS5649378A JP S5649378 A JPS5649378 A JP S5649378A JP 10838979 A JP10838979 A JP 10838979A JP 10838979 A JP10838979 A JP 10838979A JP S5649378 A JPS5649378 A JP S5649378A
- Authority
- JP
- Japan
- Prior art keywords
- agent
- formula
- hydroxy
- lower alkyl
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- HDHQZCHIXUUSMK-UHFFFAOYSA-N 4-hydroxy-2-quinolone Chemical compound C1=CC=C2C(O)=CC(=O)NC2=C1 HDHQZCHIXUUSMK-UHFFFAOYSA-N 0.000 abstract 1
- YVYCBOWDIMCDCZ-UHFFFAOYSA-N 6-[3-(1-ethyltetrazol-5-yl)propoxy]-3,4-dihydro-1h-quinolin-2-one Chemical compound CCN1N=NN=C1CCCOC1=CC=C(NC(=O)CC2)C2=C1 YVYCBOWDIMCDCZ-UHFFFAOYSA-N 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 239000000924 antiasthmatic agent Substances 0.000 abstract 1
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 239000003699 antiulcer agent Substances 0.000 abstract 1
- 150000007514 bases Chemical class 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000002571 phosphodiesterase inhibitor Substances 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 150000003536 tetrazoles Chemical class 0.000 abstract 1
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10838979A JPS5649378A (en) | 1979-08-25 | 1979-08-25 | Tetrazolylalkoxycarbostyril derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10838979A JPS5649378A (en) | 1979-08-25 | 1979-08-25 | Tetrazolylalkoxycarbostyril derivative |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP6134980A Division JPS5632471A (en) | 1980-05-08 | 1980-05-08 | Tetrazole derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5649378A true JPS5649378A (en) | 1981-05-02 |
| JPS6320235B2 JPS6320235B2 (enrdf_load_stackoverflow) | 1988-04-26 |
Family
ID=14483518
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10838979A Granted JPS5649378A (en) | 1979-08-25 | 1979-08-25 | Tetrazolylalkoxycarbostyril derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5649378A (enrdf_load_stackoverflow) |
Cited By (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5859980A (ja) * | 1981-10-05 | 1983-04-09 | Otsuka Pharmaceut Co Ltd | カルボスチリル誘導体 |
| JPS5877880A (ja) * | 1981-11-05 | 1983-05-11 | Otsuka Pharmaceut Co Ltd | テトラゾ−ル誘導体 |
| JPS6079501A (ja) * | 1983-10-05 | 1985-05-07 | Matsushita Electric Ind Co Ltd | ト−ンア−ム位置検出装置 |
| JPS6345220A (ja) * | 1986-04-02 | 1988-02-26 | Otsuka Pharmaceut Co Ltd | 血小板粘着抑制剤 |
| JPS646271A (en) * | 1986-04-02 | 1989-01-10 | Otsuka Pharma Co Ltd | Carbostyril derivative |
| WO1991010419A1 (en) * | 1990-01-08 | 1991-07-25 | Otsuka Pharmaceutical Co., Ltd. | Hair tonic and dressing composition |
| WO1994014444A1 (en) * | 1992-12-24 | 1994-07-07 | Otsuka Pharmaceutical Co., Ltd. | Psoriasis remedy |
| WO2002090351A1 (fr) * | 1999-11-24 | 2002-11-14 | Otsuka Pharmaceutical Co., Ltd. | Procede de production d'un derive carbostyrile |
| WO2002102383A1 (fr) * | 2001-06-13 | 2002-12-27 | Otsuka Pharmaceutical Factory, Inc. | Preparation de cilostazol aqueuse pour injections |
| US6630590B1 (en) | 1999-11-24 | 2003-10-07 | Otsuka Pharmaceutical Co., Ltd. | Process for producing carbostyril derivatives |
| US6743806B2 (en) | 2002-10-23 | 2004-06-01 | Otsuka Pharmaceutical Company, Limited | Active oxygen scavenger |
| WO2004075897A1 (en) * | 2003-02-25 | 2004-09-10 | Otsuka Pharmaceutical Co., Ltd. | Pten inhibitor or maxi-k channels opener |
| KR100459974B1 (ko) * | 2001-06-27 | 2004-12-04 | 오쓰까 세이야꾸 가부시키가이샤 | 카르보스티릴 유도체의 제조방법 |
| US7399864B2 (en) | 2001-05-02 | 2008-07-15 | Otsuka Pharmaceutical Co., Ltd. | Process for producing carbostyril derivatives |
| US7825251B2 (en) | 2001-05-02 | 2010-11-02 | Otsuka Pharmaceutical Co., Ltd. | Process for producing carbostyril derivatives |
| WO2011158110A2 (en) | 2010-04-28 | 2011-12-22 | Nuformix Limited | Cilostazol cocrystals and compositions |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0637925U (ja) * | 1992-10-15 | 1994-05-20 | 東京特殊電線株式会社 | デジタイザー用センサー板 |
| AR065588A1 (es) | 2007-03-09 | 2009-06-17 | Otsuka Pharma Co Ltd | Un medicamento para tratar enfermedad pulmonar obstructiva cronica |
| TW200848041A (en) | 2007-03-30 | 2008-12-16 | Otsuka Pharma Co Ltd | A medicament for treating schizophrenia comprising cilostazol |
| DK2157973T3 (en) | 2007-05-22 | 2015-08-17 | Univ Juntendo | DRUG COMPREHENSIVE A carbostyril derivative donepezil AND TREATMENT Alzheimer's disease |
-
1979
- 1979-08-25 JP JP10838979A patent/JPS5649378A/ja active Granted
Cited By (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5859980A (ja) * | 1981-10-05 | 1983-04-09 | Otsuka Pharmaceut Co Ltd | カルボスチリル誘導体 |
| JPS5877880A (ja) * | 1981-11-05 | 1983-05-11 | Otsuka Pharmaceut Co Ltd | テトラゾ−ル誘導体 |
| JPS6079501A (ja) * | 1983-10-05 | 1985-05-07 | Matsushita Electric Ind Co Ltd | ト−ンア−ム位置検出装置 |
| JPS6345220A (ja) * | 1986-04-02 | 1988-02-26 | Otsuka Pharmaceut Co Ltd | 血小板粘着抑制剤 |
| JPS646271A (en) * | 1986-04-02 | 1989-01-10 | Otsuka Pharma Co Ltd | Carbostyril derivative |
| WO1991010419A1 (en) * | 1990-01-08 | 1991-07-25 | Otsuka Pharmaceutical Co., Ltd. | Hair tonic and dressing composition |
| EP0463173B1 (en) * | 1990-01-08 | 1994-12-07 | Otsuka Pharmaceutical Co., Ltd. | Hair tonic and dressing composition |
| WO1994014444A1 (en) * | 1992-12-24 | 1994-07-07 | Otsuka Pharmaceutical Co., Ltd. | Psoriasis remedy |
| US6630590B1 (en) | 1999-11-24 | 2003-10-07 | Otsuka Pharmaceutical Co., Ltd. | Process for producing carbostyril derivatives |
| WO2002090351A1 (fr) * | 1999-11-24 | 2002-11-14 | Otsuka Pharmaceutical Co., Ltd. | Procede de production d'un derive carbostyrile |
| US7399864B2 (en) | 2001-05-02 | 2008-07-15 | Otsuka Pharmaceutical Co., Ltd. | Process for producing carbostyril derivatives |
| US7825251B2 (en) | 2001-05-02 | 2010-11-02 | Otsuka Pharmaceutical Co., Ltd. | Process for producing carbostyril derivatives |
| WO2002102383A1 (fr) * | 2001-06-13 | 2002-12-27 | Otsuka Pharmaceutical Factory, Inc. | Preparation de cilostazol aqueuse pour injections |
| KR100459974B1 (ko) * | 2001-06-27 | 2004-12-04 | 오쓰까 세이야꾸 가부시키가이샤 | 카르보스티릴 유도체의 제조방법 |
| US6743806B2 (en) | 2002-10-23 | 2004-06-01 | Otsuka Pharmaceutical Company, Limited | Active oxygen scavenger |
| WO2004075897A1 (en) * | 2003-02-25 | 2004-09-10 | Otsuka Pharmaceutical Co., Ltd. | Pten inhibitor or maxi-k channels opener |
| JP2006518732A (ja) * | 2003-02-25 | 2006-08-17 | 大塚製薬株式会社 | ＰＴＥＮ阻害剤またはＭａｘｉ−Ｋチャンネルオープナー |
| JP2010285456A (ja) * | 2003-02-25 | 2010-12-24 | Otsuka Pharmaceut Co Ltd | ＰＴＥＮ阻害剤またはＭａｘｉ−Ｋチャンネルオープナー |
| WO2011158110A2 (en) | 2010-04-28 | 2011-12-22 | Nuformix Limited | Cilostazol cocrystals and compositions |
| US8779146B2 (en) | 2010-04-28 | 2014-07-15 | Nuformix Limited | Cilostazol cocrystals and compositions |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6320235B2 (enrdf_load_stackoverflow) | 1988-04-26 |
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