JPS5649341A - Anthracyclinone and its preparation - Google Patents
Anthracyclinone and its preparationInfo
- Publication number
- JPS5649341A JPS5649341A JP11552079A JP11552079A JPS5649341A JP S5649341 A JPS5649341 A JP S5649341A JP 11552079 A JP11552079 A JP 11552079A JP 11552079 A JP11552079 A JP 11552079A JP S5649341 A JPS5649341 A JP S5649341A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- anthracyclinone
- actinomyces
- ferm
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- AOJJSUZBOXZQNB-TZSSRYMLSA-N Doxorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 AOJJSUZBOXZQNB-TZSSRYMLSA-N 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 241000186046 Actinomyces Species 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 229940009456 adriamycin Drugs 0.000 abstract 2
- 239000002246 antineoplastic agent Substances 0.000 abstract 2
- 229940127089 cytotoxic agent Drugs 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- STQGQHZAVUOBTE-UHFFFAOYSA-N 7-Cyan-hept-2t-en-4,6-diinsaeure Natural products C1=2C(O)=C3C(=O)C=4C(OC)=CC=CC=4C(=O)C3=C(O)C=2CC(O)(C(C)=O)CC1OC1CC(N)C(O)C(C)O1 STQGQHZAVUOBTE-UHFFFAOYSA-N 0.000 abstract 1
- WEAHRLBPCANXCN-UHFFFAOYSA-N Daunomycin Natural products CCC1(O)CC(OC2CC(N)C(O)C(C)O2)c3cc4C(=O)c5c(OC)cccc5C(=O)c4c(O)c3C1 WEAHRLBPCANXCN-UHFFFAOYSA-N 0.000 abstract 1
- 241001467544 Streptomyces galilaeus Species 0.000 abstract 1
- 230000003327 cancerostatic effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- STQGQHZAVUOBTE-VGBVRHCVSA-N daunorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(C)=O)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 STQGQHZAVUOBTE-VGBVRHCVSA-N 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- CPUWOKRFRYWIHK-YAPFQWMQSA-N methyl (1r,2r,4s)-4-[(2r,4s,5s,6s)-4-(dimethylamino)-5-[(2s,4s,5s,6s)-4-hydroxy-5-[(2s,5r,6s)-5-hydroxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-2-ethyl-2,5,7-trihydroxy-6,11-dioxo-3,4-dihydro-1h-tetracene-1-carboxylate Chemical compound O([C@H]1[C@@H](O)C[C@@H](O[C@H]1C)O[C@H]1[C@H](C[C@@H](O[C@H]1C)O[C@H]1C[C@]([C@@H](C2=CC=3C(=O)C4=CC=CC(O)=C4C(=O)C=3C(O)=C21)C(=O)OC)(O)CC)N(C)C)[C@H]1CC[C@@H](O)[C@H](C)O1 CPUWOKRFRYWIHK-YAPFQWMQSA-N 0.000 abstract 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11552079A JPS5649341A (en) | 1979-09-07 | 1979-09-07 | Anthracyclinone and its preparation |
| EP80105306A EP0030255B1 (en) | 1979-09-07 | 1980-09-04 | 2-hydroxyaclacinomycin a, pharmaceutical composition containing it; 2-hydroxyaclavinone and fermentative process for preparing same |
| DE8080105306T DE3071391D1 (en) | 1979-09-07 | 1980-09-04 | 2-hydroxyaclacinomycin a, pharmaceutical composition containing it; 2-hydroxyaclavinone and fermentative process for preparing same |
| CA000359645A CA1156577A (en) | 1979-09-07 | 1980-09-05 | Process for preparing 2-hydroxyaklavinone and 2-hydroxyaclacinomycin-a |
| US06/184,518 US4386198A (en) | 1979-09-07 | 1980-09-05 | 2-Hydroxyaclacinomycin A and 2-hydroxyaklavinone and process for preparing same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11552079A JPS5649341A (en) | 1979-09-07 | 1979-09-07 | Anthracyclinone and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5649341A true JPS5649341A (en) | 1981-05-02 |
| JPS627905B2 JPS627905B2 (enrdf_load_stackoverflow) | 1987-02-19 |
Family
ID=14664550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP11552079A Granted JPS5649341A (en) | 1979-09-07 | 1979-09-07 | Anthracyclinone and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5649341A (enrdf_load_stackoverflow) |
-
1979
- 1979-09-07 JP JP11552079A patent/JPS5649341A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS627905B2 (enrdf_load_stackoverflow) | 1987-02-19 |
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