JPS5738796A - Tetrocarcins and their preparations - Google Patents

Tetrocarcins and their preparations

Info

Publication number
JPS5738796A
JPS5738796A JP11437380A JP11437380A JPS5738796A JP S5738796 A JPS5738796 A JP S5738796A JP 11437380 A JP11437380 A JP 11437380A JP 11437380 A JP11437380 A JP 11437380A JP S5738796 A JPS5738796 A JP S5738796A
Authority
JP
Japan
Prior art keywords
tetrocarcin
adsorbed
formula
tetrocarcins
compound shown
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP11437380A
Other languages
Japanese (ja)
Other versions
JPS6338038B2 (en
Inventor
Fusao Tomita
Tatsuya Tamaoki
Kimikatsu Shirahata
Masaji Kasai
Kazuyuki Mineura
Shinzo Ishii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP11437380A priority Critical patent/JPS5738796A/en
Priority to US06/252,062 priority patent/US4346075A/en
Publication of JPS5738796A publication Critical patent/JPS5738796A/en
Publication of JPS6338038B2 publication Critical patent/JPS6338038B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A compound shown by the formula(R1 and R2 are H or acetyl with the proviso that R1 is not R2) and its salt.
EXAMPLE: Tetrocarcin E-1.
USE: An antibiotic. Having antibacterial actions and antitumor actions.
PROCESS: A bacterium[e.g., "Micromonospora chalcea" KY 11091(FERM-P 4458, NRRL 11,289), etc.] belonging to the genus "Micromonospora", having tetrocarcin E-1 and/or tetrocarcin E-2 producing ability, is subjected to liquid culture in a nutrient medium at 25W40°C, preferably at 28W38°C, in a pH 4W10. The culture solution is passed through a nonionic porous resin, so that a component having antibacterial activity is adsorbed on it. The adsorbed substance is desorbed with methanol, etc., adsorbed on active carbon, and eluted with a solvent, e.g., acetone, etc., to give a mixure of tetrocarcins, from which a compound shown by the formula is collected.
COPYRIGHT: (C)1982,JPO&Japio
JP11437380A 1980-06-14 1980-08-20 Tetrocarcins and their preparations Granted JPS5738796A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP11437380A JPS5738796A (en) 1980-08-20 1980-08-20 Tetrocarcins and their preparations
US06/252,062 US4346075A (en) 1980-06-14 1981-04-08 Antibiotic DC-11 and process for production thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11437380A JPS5738796A (en) 1980-08-20 1980-08-20 Tetrocarcins and their preparations

Publications (2)

Publication Number Publication Date
JPS5738796A true JPS5738796A (en) 1982-03-03
JPS6338038B2 JPS6338038B2 (en) 1988-07-28

Family

ID=14636067

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11437380A Granted JPS5738796A (en) 1980-06-14 1980-08-20 Tetrocarcins and their preparations

Country Status (1)

Country Link
JP (1) JPS5738796A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000012494A1 (en) * 1998-08-31 2000-03-09 Kyowa Hakko Kogyo Co., Ltd. Apoptosis inducing agents

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2021009065A (en) 2019-01-29 2021-08-18 Jfe Steel Corp High-strength hot-dip galvanized steel sheet and manufacturing method therefor.

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000012494A1 (en) * 1998-08-31 2000-03-09 Kyowa Hakko Kogyo Co., Ltd. Apoptosis inducing agents
US6548536B2 (en) 1998-08-31 2003-04-15 Kyowa Hakko Kogyo Co., Ltd. Agent for inducing apoptosis

Also Published As

Publication number Publication date
JPS6338038B2 (en) 1988-07-28

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