JPS56122392A - Dc-11-a-2 - Google Patents
Dc-11-a-2Info
- Publication number
- JPS56122392A JPS56122392A JP2492480A JP2492480A JPS56122392A JP S56122392 A JPS56122392 A JP S56122392A JP 2492480 A JP2492480 A JP 2492480A JP 2492480 A JP2492480 A JP 2492480A JP S56122392 A JPS56122392 A JP S56122392A
- Authority
- JP
- Japan
- Prior art keywords
- methanol
- agent
- soluble
- substance
- fermp4458
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
NEW MATERIAL:An antimicrobial agent DC-11-A-2. Melting point: 192W196°C. Elemental analysis: C 60.8%, H 7.4%, N 2.3%. Specific rotatory power: [α]D19= -55.8(C=1.00 acetone). Solubility, soluble in methanol, ethanol, etc., slightly soluble in benzene and water, insoluble in petroleum ether and n-hexane.
USE: An antitumor agent or antibacterial agent. Usually being administered in the vein or abdominal cavity as an injection.
PROCESS: For example, Micromonospora chalcea, KY11091 strain (FERMP4458), is subjected to liquid cultivation under aerobical conditions, and the desired substance is adsorbed from the filtrate on a nonionic porous resin, etc., and desorbed by methanol, etc. The resulting substance is purified and separated by adsorption and desorption by active carbon, silica gel chromatography, etc., to give DC-11-A-2.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2492480A JPS56122392A (en) | 1980-02-29 | 1980-02-29 | Dc-11-a-2 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2492480A JPS56122392A (en) | 1980-02-29 | 1980-02-29 | Dc-11-a-2 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56122392A true JPS56122392A (en) | 1981-09-25 |
JPS6253518B2 JPS6253518B2 (en) | 1987-11-10 |
Family
ID=12151672
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2492480A Granted JPS56122392A (en) | 1980-02-29 | 1980-02-29 | Dc-11-a-2 |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56122392A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4692333A (en) * | 1982-08-26 | 1987-09-08 | Gruppo Lepetit S.P.A. | Antimicrobial and antitumor antibiotic M 9026 and its pure individual factors 1, 2, and 3 and microbial process for production thereof |
WO2000012494A1 (en) * | 1998-08-31 | 2000-03-09 | Kyowa Hakko Kogyo Co., Ltd. | Apoptosis inducing agents |
-
1980
- 1980-02-29 JP JP2492480A patent/JPS56122392A/en active Granted
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4692333A (en) * | 1982-08-26 | 1987-09-08 | Gruppo Lepetit S.P.A. | Antimicrobial and antitumor antibiotic M 9026 and its pure individual factors 1, 2, and 3 and microbial process for production thereof |
WO2000012494A1 (en) * | 1998-08-31 | 2000-03-09 | Kyowa Hakko Kogyo Co., Ltd. | Apoptosis inducing agents |
US6548536B2 (en) | 1998-08-31 | 2003-04-15 | Kyowa Hakko Kogyo Co., Ltd. | Agent for inducing apoptosis |
Also Published As
Publication number | Publication date |
---|---|
JPS6253518B2 (en) | 1987-11-10 |
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