JPS5622770A - Amidine derivative and its preparation - Google Patents

Amidine derivative and its preparation

Info

Publication number
JPS5622770A
JPS5622770A JP9890679A JP9890679A JPS5622770A JP S5622770 A JPS5622770 A JP S5622770A JP 9890679 A JP9890679 A JP 9890679A JP 9890679 A JP9890679 A JP 9890679A JP S5622770 A JPS5622770 A JP S5622770A
Authority
JP
Japan
Prior art keywords
formula
alkyl
activity
hydroxyl
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP9890679A
Other languages
English (en)
Other versions
JPS6056143B2 (ja
Inventor
Yasufumi Hirata
Isao Yanagisawa
Yoshio Ishii
Shinichi Tsukamoto
Tokuki Ito
Yasuo Isomura
Masaaki Takeda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=14232166&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPS5622770(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to JP54098906A priority Critical patent/JPS6056143B2/ja
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Priority to GB7943945A priority patent/GB2055800B/en
Priority to DE2951675A priority patent/DE2951675C2/de
Priority to PH23454A priority patent/PH15657A/en
Priority to SE7910568A priority patent/SE444317B/sv
Priority to CH11362/79A priority patent/CH648027A5/de
Priority to NLAANVRAGE7909321,A priority patent/NL180420C/xx
Priority to US06/107,629 priority patent/US4283408A/en
Priority to ES487381A priority patent/ES8100281A1/es
Priority to CA000342699A priority patent/CA1134836A/en
Priority to FR797931938A priority patent/FR2462431B1/fr
Priority to IT69498/79A priority patent/IT1119641B/it
Priority to AT0103080A priority patent/AT374800B/de
Priority to FI800591A priority patent/FI70890C/fi
Priority to AU55975/80A priority patent/AU534329B2/en
Priority to GR61334A priority patent/GR67011B/el
Priority to PT70899A priority patent/PT70899A/pt
Priority to SU802891152A priority patent/SU876056A3/ru
Priority to MX8011198U priority patent/MX7406E/es
Priority to MX8011289U priority patent/MX7292E/es
Priority to DK093580A priority patent/DK157132C/da
Priority to UA2891152A priority patent/UA5926A1/uk
Priority to SI8010622A priority patent/SI8010622A8/sl
Priority to YU622/80A priority patent/YU42966B/xx
Publication of JPS5622770A publication Critical patent/JPS5622770A/ja
Publication of JPS6056143B2 publication Critical patent/JPS6056143B2/ja
Priority to CA000521982A priority patent/CA1222763B/en
Priority to NL930038C priority patent/NL930038I2/nl
Priority to LV930547A priority patent/LV5493A3/xx
Priority to GEAP19942152A priority patent/GEP19970667B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/40—Unsubstituted amino or imino radicals
JP54098906A 1979-03-06 1979-08-02 アミジン誘導体ならびにその製造法 Expired JPS6056143B2 (ja)

Priority Applications (28)

Application Number Priority Date Filing Date Title
JP54098906A JPS6056143B2 (ja) 1979-08-02 1979-08-02 アミジン誘導体ならびにその製造法
GB7943945A GB2055800B (en) 1979-08-02 1979-12-20 Guanidinothiazoles and their preparation and use
DE2951675A DE2951675C2 (de) 1979-08-02 1979-12-21 Guanidinothiazolverbindungen, Verfahren zu deren Herstellung und Arzneimittelzubereitungen
PH23454A PH15657A (en) 1979-08-02 1979-12-21 Guanidinothiazole compounds,process for preparation and gastric inhibiting compositions containing them
SE7910568A SE444317B (sv) 1979-08-02 1979-12-21 Nya guanidinotiazolforeningar samt farmaceutiska kompositioner derav
CH11362/79A CH648027A5 (de) 1979-08-02 1979-12-24 Guanidinothiazolverbindungen, verfahren zu deren herstellung und arzneimittelzubereitungen.
US06/107,629 US4283408A (en) 1979-08-02 1979-12-27 Guanidinothiazole compounds, process for preparation and gastric inhibiting compositions containing them
NLAANVRAGE7909321,A NL180420C (nl) 1979-08-02 1979-12-27 Farmaceutische preparaten, welke een invloed op de maagzuurafscheiding bezitten en ten minste een guanidinothiazoolderivaat als werkzame stof bevatten alsmede de voor gebruik in dergelijke preparaten geschikte guanidinothiazoolderivaten.
ES487381A ES8100281A1 (es) 1979-08-02 1979-12-28 Un procedimiento para la preparacion de un compuesto de guanidinotiazol
CA000342699A CA1134836A (en) 1979-08-02 1979-12-28 Process for preparing novel guanidinothiazole compounds
FR797931938A FR2462431B1 (fr) 1979-08-02 1979-12-28 Nouveau compose du guanidinothiazole, son procede de preparation et des compositions medicales contenant de tels composes
IT69498/79A IT1119641B (it) 1979-08-02 1979-12-28 Composti del guanidinotiazolo particolarmente utili come antisecretivi gastrici e procedimento per la loro preparazione
AT0103080A AT374800B (de) 1979-03-06 1980-02-25 Verfahren zur herstellung neuer guanidinothiazole und von deren salzen
FI800591A FI70890C (fi) 1979-03-06 1980-02-27 Foerfarande foer framstaellning av farmakologiskt vaerdefulla guanidinotiazolfoereningar
AU55975/80A AU534329B2 (en) 1979-03-06 1980-02-28 Guanioinothiazoles
GR61334A GR67011B (ja) 1979-03-06 1980-03-03
PT70899A PT70899A (en) 1979-03-06 1980-03-04 Process for preparing useful guanidinothiazole compounds
SU802891152A SU876056A3 (ru) 1979-03-06 1980-03-05 Способ получени гуанидинотиазольных соединений
MX8011198U MX7406E (es) 1979-03-06 1980-03-05 Procedimiento para preparar compuestos de guanidinotiazol
MX8011289U MX7292E (es) 1979-03-06 1980-03-05 Procedimiento para preparar compuestos de guanidinotiazol
DK093580A DK157132C (da) 1979-03-06 1980-03-05 Analogifremgangsmaade til fremstilling af guanidinothiazolforbindelser eller syreadditionssalte deraf
UA2891152A UA5926A1 (uk) 1979-03-06 1980-03-05 Спосіб одержання гуанідінотіазольних сполучень
YU622/80A YU42966B (en) 1979-03-06 1980-03-06 Process for obtaining guanidine thiazole compounds
SI8010622A SI8010622A8 (sl) 1979-03-06 1980-03-06 Postopek pridobivanja gvanidintiazolnih spojin
CA000521982A CA1222763B (en) 1979-08-02 1986-10-31 Process for preparing novel guanidinothiazole compounds
NL930038C NL930038I2 (nl) 1979-08-02 1993-05-19 Farmaceutische preparaten, welke een invloed op demaagzuurafscheiding bezitten en ten minste een qu anidinothiazoolderivaat als werkzame stof bevattenalsmede de voor gebruik in dergelijke preparaten geschikte quanidinothiazoolderivaten.
LV930547A LV5493A3 (lv) 1979-03-06 1993-11-30 Guanidinotiazolu savienojumu iegusanas panemiens
GEAP19942152A GEP19970667B (en) 1979-03-06 1994-09-07 Method of producing guanidinothiazole compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP54098906A JPS6056143B2 (ja) 1979-08-02 1979-08-02 アミジン誘導体ならびにその製造法

Publications (2)

Publication Number Publication Date
JPS5622770A true JPS5622770A (en) 1981-03-03
JPS6056143B2 JPS6056143B2 (ja) 1985-12-09

Family

ID=14232166

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54098906A Expired JPS6056143B2 (ja) 1979-03-06 1979-08-02 アミジン誘導体ならびにその製造法

Country Status (12)

Country Link
US (1) US4283408A (ja)
JP (1) JPS6056143B2 (ja)
CA (2) CA1134836A (ja)
CH (1) CH648027A5 (ja)
DE (1) DE2951675C2 (ja)
ES (1) ES8100281A1 (ja)
FR (1) FR2462431B1 (ja)
GB (1) GB2055800B (ja)
IT (1) IT1119641B (ja)
NL (2) NL180420C (ja)
PH (1) PH15657A (ja)
SE (1) SE444317B (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6399065A (ja) * 1986-08-05 1988-04-30 リヒタ−　ゲデオン　ベジエセテイ　ジヤ−ル　ア−ル．テ−． 形態学的に均質型のチアゾ−ル誘導体の製造方法

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DE3267110D1 (de) * 1981-05-18 1985-12-05 Ici Plc Amidine derivatives
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1338169A (en) * 1971-03-09 1973-11-21 Smith Kline French Lab Ureas thioureas and guanidines
US4165378A (en) * 1977-04-20 1979-08-21 Ici Americas Inc. Guanidine derivatives of imidazoles and thiazoles
ZA782129B (en) * 1977-04-20 1979-03-28 Ici Ltd Hertocyclic derivatives

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6399065A (ja) * 1986-08-05 1988-04-30 リヒタ−　ゲデオン　ベジエセテイ　ジヤ−ル　ア−ル．テ−． 形態学的に均質型のチアゾ−ル誘導体の製造方法
JPH07316141A (ja) * 1986-08-05 1995-12-05 Richter Gedeon V G Rt 形態学的に均質型のチアゾール誘導体の製造方法

Also Published As

Publication number Publication date
SE444317B (sv) 1986-04-07
CA1222763B (en) 1987-06-09
IT1119641B (it) 1986-03-10
DE2951675C2 (de) 1982-07-01
NL930038I1 (nl) 1993-08-02
US4283408A (en) 1981-08-11
NL7909321A (nl) 1981-02-04
CH648027A5 (de) 1985-02-28
GB2055800B (en) 1983-05-11
NL180420B (nl) 1986-09-16
ES487381A0 (es) 1980-11-01
NL180420C (nl) 1987-02-16
JPS6056143B2 (ja) 1985-12-09
CA1134836A (en) 1982-11-02
ES8100281A1 (es) 1980-11-01
DE2951675A1 (de) 1981-02-05
GB2055800A (en) 1981-03-11
PH15657A (en) 1983-03-11
FR2462431B1 (fr) 1985-07-26
SE7910568L (sv) 1981-02-03
NL930038I2 (nl) 1993-10-01
FR2462431A1 (fr) 1981-02-13
IT7969498A0 (it) 1979-12-28

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