FR2462431B1 - Nouveau compose du guanidinothiazole, son procede de preparation et des compositions medicales contenant de tels composes - Google Patents
Nouveau compose du guanidinothiazole, son procede de preparation et des compositions medicales contenant de tels composesInfo
- Publication number
- FR2462431B1 FR2462431B1 FR797931938A FR7931938A FR2462431B1 FR 2462431 B1 FR2462431 B1 FR 2462431B1 FR 797931938 A FR797931938 A FR 797931938A FR 7931938 A FR7931938 A FR 7931938A FR 2462431 B1 FR2462431 B1 FR 2462431B1
- Authority
- FR
- France
- Prior art keywords
- novel
- compounds
- compositions containing
- preparing same
- medical compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP54098906A JPS6056143B2 (ja) | 1979-08-02 | 1979-08-02 | アミジン誘導体ならびにその製造法 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2462431A1 FR2462431A1 (fr) | 1981-02-13 |
FR2462431B1 true FR2462431B1 (fr) | 1985-07-26 |
Family
ID=14232166
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR797931938A Expired FR2462431B1 (fr) | 1979-08-02 | 1979-12-28 | Nouveau compose du guanidinothiazole, son procede de preparation et des compositions medicales contenant de tels composes |
Country Status (12)
Country | Link |
---|---|
US (1) | US4283408A (fr) |
JP (1) | JPS6056143B2 (fr) |
CA (2) | CA1134836A (fr) |
CH (1) | CH648027A5 (fr) |
DE (1) | DE2951675C2 (fr) |
ES (1) | ES8100281A1 (fr) |
FR (1) | FR2462431B1 (fr) |
GB (1) | GB2055800B (fr) |
IT (1) | IT1119641B (fr) |
NL (2) | NL180420C (fr) |
PH (1) | PH15657A (fr) |
SE (1) | SE444317B (fr) |
Families Citing this family (91)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA782129B (en) * | 1977-04-20 | 1979-03-28 | Ici Ltd | Hertocyclic derivatives |
PH16099A (en) * | 1979-03-06 | 1983-06-24 | Yamanouchi Pharma Co Ltd | Guanidinothiazole compounds,process for preparing them and medical composition containing them |
GR71929B (fr) * | 1979-11-13 | 1983-08-19 | Ici Ltd | |
DE3168031D1 (en) * | 1980-07-30 | 1985-02-14 | Ici Plc | Guanidine derivatives |
US4382090A (en) * | 1980-10-02 | 1983-05-03 | Eli Lilly And Company | N-Thiazolylmethylthioalkyl-N'alkylamidines and related compounds |
IN158869B (fr) * | 1981-03-18 | 1987-02-07 | Ici Plc | |
DE3267110D1 (de) * | 1981-05-18 | 1985-12-05 | Ici Plc | Amidine derivatives |
DE3238867A1 (de) * | 1982-10-20 | 1984-04-26 | Ludwig Heumann & Co GmbH, 8500 Nürnberg | Heterocyclische verbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
JPS59104370A (ja) * | 1982-12-03 | 1984-06-16 | Kotobuki Seiyaku Kk | チアゾ−ル誘導体及びその製造方法 |
JPS59227870A (ja) * | 1983-06-07 | 1984-12-21 | Yamanouchi Pharmaceut Co Ltd | 新規2−グアニジノチアゾリン誘導体ならびにその製造法 |
US4497810A (en) * | 1983-10-14 | 1985-02-05 | Merck & Co., Inc. | Thiatriazine dioxides as gastric anti-secretory agents |
US4663347A (en) | 1983-10-31 | 1987-05-05 | Merck Frosst Canada, Inc. | Benzofuran 2-carboxylic acid esters useful as inhibitors of leukotriene biosynthesis |
CA1269382A (fr) * | 1984-04-18 | 1990-05-22 | Jose A. Ortiz | Sulfonamidines anti-ulcereuses |
US4560690A (en) * | 1984-04-30 | 1985-12-24 | Pfizer Inc. | 2-(N-substituted guanidino)-4-hetero-arylthiazole antiulcer agents |
JPS6160673A (ja) * | 1984-08-30 | 1986-03-28 | Yamanouchi Pharmaceut Co Ltd | グアニジノチアゾ−ル誘導体の製造法 |
CA1309557C (fr) | 1985-06-18 | 1992-10-27 | Robert N. Young | Antagonistes de leucotrienes |
HU194845B (en) * | 1985-09-11 | 1988-03-28 | Richter Gedeon Vegyeszet | Process for production of n-sulphamil-3-/2-guanidintiazolil-4-methil-tio/-propion-amidin |
DE3786030T2 (de) | 1986-03-27 | 1993-12-02 | Merck Frosst Canada Inc | Tetrahydrocarbazole Ester. |
DE3644246A1 (de) * | 1986-06-20 | 1987-12-23 | Uriach & Cia Sa J | Verfahren zur herstelung von 3-(((2-((aminoiminomethyl)-amino)-4-thiazolyl)-methyl)-thio)-n-(aminosulfonyl)-propanimidamid |
HU196775B (en) * | 1986-08-05 | 1989-01-30 | Richter Gedeon Vegyeszet | Process for production of morfologically unique new modifications of famotidin and medical compositions containing such substances |
ES2008810A6 (es) * | 1988-07-18 | 1989-08-01 | Marga Investigacion | Procedimiento de preparacion de derivados de n-sulfamil-propionamidina. |
HUT61980A (en) | 1990-10-12 | 1993-03-29 | Merck Frosst Canada Inc | Process for producing saturated hydroxyalkylquinoline acids and pharmaceutical compositions comprising such compounds as active ingredient |
US5294433A (en) * | 1992-04-15 | 1994-03-15 | The Procter & Gamble Company | Use of H-2 antagonists for treatment of gingivitis |
CA2110313C (fr) * | 1992-12-01 | 2004-10-26 | Edward John Roche | Compositions pharmaceutiques contenant un compose de guanidothiazole et antiacides |
US5410054A (en) * | 1993-07-20 | 1995-04-25 | Merck Frosst Canada, Inc. | Heteroaryl quinolines as inhibitors of leukotriene biosynthesis |
US5593696A (en) * | 1994-11-21 | 1997-01-14 | Mcneil-Ppc, Inc. | Stabilized composition of famotidine and sucralfate for treatment of gastrointestinal disorders |
US5650421A (en) * | 1995-03-31 | 1997-07-22 | Baxter International Inc. | Premixed famotidine formulation |
US5667794A (en) * | 1995-05-02 | 1997-09-16 | Merck & Co., Inc. | Heartburn treatment |
US5854267A (en) * | 1995-06-02 | 1998-12-29 | Merck & Co., Inc. | Method for preventing heartburn |
KR0168978B1 (ko) * | 1995-07-12 | 1999-01-15 | 김종인 | 헤테로고리 접합 티아졸 유도체 |
US5989588A (en) * | 1996-10-04 | 1999-11-23 | Merck & Co., Inc. | Methods and compositions for preventing and treating heartburn |
US6949264B1 (en) | 1996-11-27 | 2005-09-27 | Wm. Wrigley Jr. Company | Nutraceuticals or nutritional supplements and method of making |
US5856500A (en) * | 1997-03-11 | 1999-01-05 | Albemarle Corporation | Synthesis of thiazole derivatives |
US5731442A (en) * | 1997-03-11 | 1998-03-24 | Albemarle Corporation | Synthesis of thiazole derivatives |
US6552047B2 (en) * | 1998-11-17 | 2003-04-22 | Nitromed, Inc. | H2 receptor antagonist compounds in combination with nitric oxide donors, compositions and methods of use |
US7163705B2 (en) | 1998-12-15 | 2007-01-16 | Wm. Wrigley Jr. Company | Coated chewing gum product and method of making |
US6531114B1 (en) | 1999-04-06 | 2003-03-11 | Wm. Wrigley Jr. Company | Sildenafil citrate chewing gum formulations and methods of using the same |
US6586023B1 (en) | 1998-12-15 | 2003-07-01 | Wm. Wrigley Jr. Company | Process for controlling release of active agents from a chewing gum coating and product thereof |
US6627234B1 (en) | 1998-12-15 | 2003-09-30 | Wm. Wrigley Jr. Company | Method of producing active agent coated chewing gum products |
US6270807B1 (en) | 1999-03-02 | 2001-08-07 | L. Perrigo Company | Taste-masked pharmaceutical composition |
US6322806B1 (en) | 1999-04-06 | 2001-11-27 | Wm. Wrigley Jr. Company | Over-coated chewing gum formulations including tableted center |
US6773716B2 (en) | 1999-04-06 | 2004-08-10 | Wm. Wrigley Jr. Company | Over-coated chewing gum formulations |
US7935362B2 (en) | 1999-04-06 | 2011-05-03 | Wm. Wrigley Jr. Company | Over-coated product including consumable center and medicament |
AU784112B2 (en) * | 1999-04-06 | 2006-02-09 | Wm. Wrigley Jr. Company | Pharmaceutical chewing gum formulations |
US6355265B1 (en) | 1999-04-06 | 2002-03-12 | Wm. Wrigley Jr. Company | Over-coated chewing gum formulations |
US6569472B1 (en) | 2000-09-01 | 2003-05-27 | Wm. Wrigley Jr. Company | Coated chewing gum products containing antacid and method of making |
US6645535B2 (en) | 1999-09-02 | 2003-11-11 | Wm. Wrigley Jr. Company | Method of making coated chewing gum products containing various antacids |
US6663849B1 (en) | 2000-09-01 | 2003-12-16 | Wm. Wrigley Jr. Company | Antacid chewing gum products coated with high viscosity materials |
US6541048B2 (en) | 1999-09-02 | 2003-04-01 | Wm. Wrigley Jr. Company | Coated chewing gum products containing an acid blocker and process of preparing |
US9387168B2 (en) | 1999-09-20 | 2016-07-12 | Jack Barreca | Chewing gum with tomatidine |
AU3885201A (en) | 1999-09-20 | 2001-04-24 | Mastercare | Diet and weight control gum and sucker |
US9253991B2 (en) | 1999-09-20 | 2016-02-09 | Jack Barreca | Chewing gum with B vitamins |
US7115288B2 (en) | 2000-06-09 | 2006-10-03 | Wm. Wrigley Jr. Company | Method for making coated chewing gum products with a coating including an aldehyde flavor and a dipeptide sweetener |
US6572900B1 (en) | 2000-06-09 | 2003-06-03 | Wm. Wrigley, Jr. Company | Method for making coated chewing gum products including a high-intensity sweetener |
US6444241B1 (en) | 2000-08-30 | 2002-09-03 | Wm. Wrigley Jr. Company | Caffeine coated chewing gum product and process of making |
US6579545B2 (en) | 2000-12-22 | 2003-06-17 | Wm. Wrigley Jr. Company | Coated chewing gum products containing an antigas agent |
SE0101379D0 (sv) * | 2001-04-18 | 2001-04-18 | Diabact Ab | Komposition som hämmar utsöndring av magsyra |
SE0203065D0 (sv) | 2002-10-16 | 2002-10-16 | Diabact Ab | Gastric acid secretion inhibiting composition |
TW200517114A (en) | 2003-10-15 | 2005-06-01 | Combinatorx Inc | Methods and reagents for the treatment of immunoinflammatory disorders |
EP1579862A1 (fr) | 2004-03-25 | 2005-09-28 | Boehringer Ingelheim Vetmedica Gmbh | Utilisation des inhibiteurs de PDE III pour la réduction de la taille du coeur chez des mammifères souffrant d'insufficances cardiaques |
US8980894B2 (en) | 2004-03-25 | 2015-03-17 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure |
US20080045575A1 (en) * | 2004-12-29 | 2008-02-21 | Van Dyke Thomas E | Delivery of H2 Antagonists |
US20080021078A1 (en) * | 2006-07-18 | 2008-01-24 | Horizon Therapeutics, Inc. | Methods and medicaments for administration of ibuprofen |
US20070043096A1 (en) * | 2005-07-18 | 2007-02-22 | Horizon Therapeutics, Inc. | Unit dose form with ibuprofen-famotidine admixture |
US8067451B2 (en) * | 2006-07-18 | 2011-11-29 | Horizon Pharma Usa, Inc. | Methods and medicaments for administration of ibuprofen |
US20080020040A1 (en) * | 2006-07-18 | 2008-01-24 | Horizon Therapeutics, Inc. | Unit dose form for administration of ibuprofen |
BRPI0618643A2 (pt) | 2005-11-09 | 2011-09-06 | Combinatorx Inc | composição compreendendo um par de fármacos, composição compreendendo um corticosteróide e um imunossupressor dependente de imunofilina não-esteróide, kits e uso |
US8067033B2 (en) | 2007-11-30 | 2011-11-29 | Horizon Pharma Usa, Inc. | Stable compositions of famotidine and ibuprofen |
ATE539747T1 (de) | 2006-07-18 | 2012-01-15 | Horizon Therapeutics Inc | Verfahren und medikamente zur verabreichung von ibuprofen |
WO2008027963A2 (fr) * | 2006-08-31 | 2008-03-06 | Horizon Therapeutics, Inc. | Formulations à dose unique d'ains avec antagonistes du récepteur de h2, et procédés d'utilisation |
EP1920785A1 (fr) | 2006-11-07 | 2008-05-14 | Boehringer Ingelheim Vetmedica Gmbh | Préparation liquide contenant un complexe du pimobendane et de la cyclodextrine |
US8039461B1 (en) | 2006-11-10 | 2011-10-18 | Pisgah Laboratories, Inc. | Physical states of a pharmaceutical drug substance |
US7718649B1 (en) | 2006-11-10 | 2010-05-18 | Pisgah Labs, Inc. | Physical states of a pharmaceutical drug substance |
US20090069395A1 (en) * | 2007-09-09 | 2009-03-12 | Protia, Llc | Deuterium-enriched famotidine |
CA2956278C (fr) * | 2008-01-04 | 2022-03-01 | Schabar Research Associates Llc | Compositions de doses buccales unitaires composees d'ibuprofene et de famotidine, et applications connexes |
US8883863B1 (en) | 2008-04-03 | 2014-11-11 | Pisgah Laboratories, Inc. | Safety of psuedoephedrine drug products |
WO2010021681A2 (fr) * | 2008-08-18 | 2010-02-25 | Combinatorx (Singapore) Pte. Ltd. | Compositions et procédés pour le traitement de maladies virales |
TW201105233A (en) | 2009-05-11 | 2011-02-16 | Agraquest Inc | Compounds derived from muscodor fungi |
US20110130711A1 (en) * | 2009-11-19 | 2011-06-02 | Follica, Inc. | Hair growth treatment |
HUE060093T2 (hu) | 2012-03-15 | 2023-01-28 | Boehringer Ingelheim Vetmedica Gmbh | Gyógyszerészeti tablettakészítmény az állatgyógyászati ágazat számára, eljárás annak elõállítására és annak alkalmazása |
JP6378179B2 (ja) * | 2013-07-03 | 2018-08-22 | 株式会社新日本科学 | 新規化合物,有機カチオントランスポーター3の検出剤及び活性阻害剤 |
PL3021832T3 (pl) | 2013-07-19 | 2021-08-23 | Boehringer Ingelheim Vetmedica Gmbh | Konserwowana ciekła wodna kompozycja farmaceutyczna zawierająca eteryfikowane pochodne cyklodekstryny |
DK2925305T3 (en) | 2013-12-04 | 2016-10-10 | Boehringer Ingelheim Vetmedica Gmbh | Improved pharmaceutical compositions of pimobendan. |
WO2015155297A1 (fr) | 2014-04-11 | 2015-10-15 | Sanovel Ilac Sanayi Ve Ticaret A.S. | Combinaisons pharmaceutiques de dabigatran et d'antagonistes du récepteur h2 |
WO2015163832A1 (fr) | 2014-04-25 | 2015-10-29 | Pharmacti̇ve İlaç Sanayi̇ Ve Ti̇caret A.Ş. | Composition combinée d'ibuprofène et de famotidine ayant une stabilité améliorée |
WO2015169957A1 (fr) | 2014-05-09 | 2015-11-12 | Sanovel Ilac Sanayi Ve Ticaret A.S. | Combinaisons pharmaceutiques de rivaroxaban et d'antagonistes du récepteur h2 |
US10537570B2 (en) | 2016-04-06 | 2020-01-21 | Boehringer Ingelheim Vetmedica Gmbh | Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease |
TR201618765A2 (tr) | 2016-12-16 | 2018-07-23 | Imuneks Farma Ilac Sanayi Ve Ticaret Anonim Sirketi | Ağrı ve enflamasyonun tedavisi için steroid olmayan anti-enflamatuvar ilaçlar ve H2 reseptörü antagonisti kombinasyonları. |
KR20230051164A (ko) | 2020-07-15 | 2023-04-17 | 샤바르 리서치 어소시에이츠 엘엘씨 | 급성 통증의 치료 및 속쓰림의 중증도 및/또는 위험의 감소를 위한 이부프로펜 및 파모티딘으로 구성된 단위 경구 투여 조성물 |
US11324727B2 (en) | 2020-07-15 | 2022-05-10 | Schabar Research Associates, Llc | Unit oral dose compositions composed of naproxen sodium and famotidine for the treatment of acute pain and the reduction of the severity of heartburn and/or the risk of heartburn |
EP4196793A1 (fr) | 2020-08-11 | 2023-06-21 | Université de Strasbourg | Bloqueurs de h2 ciblant des macrophages du foie pour la prévention et le traitement d'une maladie du foie et du cancer |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1338169A (en) * | 1971-03-09 | 1973-11-21 | Smith Kline French Lab | Ureas thioureas and guanidines |
ZA782129B (en) * | 1977-04-20 | 1979-03-28 | Ici Ltd | Hertocyclic derivatives |
US4165378A (en) * | 1977-04-20 | 1979-08-21 | Ici Americas Inc. | Guanidine derivatives of imidazoles and thiazoles |
-
1979
- 1979-08-02 JP JP54098906A patent/JPS6056143B2/ja not_active Expired
- 1979-12-20 GB GB7943945A patent/GB2055800B/en not_active Expired
- 1979-12-21 SE SE7910568A patent/SE444317B/sv not_active IP Right Cessation
- 1979-12-21 DE DE2951675A patent/DE2951675C2/de not_active Expired
- 1979-12-21 PH PH23454A patent/PH15657A/en unknown
- 1979-12-24 CH CH11362/79A patent/CH648027A5/de not_active IP Right Cessation
- 1979-12-27 NL NLAANVRAGE7909321,A patent/NL180420C/xx not_active IP Right Cessation
- 1979-12-27 US US06/107,629 patent/US4283408A/en not_active Expired - Lifetime
- 1979-12-28 ES ES487381A patent/ES8100281A1/es not_active Expired
- 1979-12-28 FR FR797931938A patent/FR2462431B1/fr not_active Expired
- 1979-12-28 CA CA000342699A patent/CA1134836A/fr not_active Expired
- 1979-12-28 IT IT69498/79A patent/IT1119641B/it active Protection Beyond IP Right Term
-
1986
- 1986-10-31 CA CA000521982A patent/CA1222763B/fr not_active Expired
-
1993
- 1993-05-19 NL NL930038C patent/NL930038I2/nl unknown
Also Published As
Publication number | Publication date |
---|---|
IT1119641B (it) | 1986-03-10 |
SE7910568L (sv) | 1981-02-03 |
NL180420B (nl) | 1986-09-16 |
NL930038I1 (nl) | 1993-08-02 |
GB2055800B (en) | 1983-05-11 |
JPS6056143B2 (ja) | 1985-12-09 |
PH15657A (en) | 1983-03-11 |
NL7909321A (nl) | 1981-02-04 |
CH648027A5 (de) | 1985-02-28 |
GB2055800A (en) | 1981-03-11 |
DE2951675C2 (de) | 1982-07-01 |
CA1222763B (fr) | 1987-06-09 |
CA1134836A (fr) | 1982-11-02 |
DE2951675A1 (de) | 1981-02-05 |
ES487381A0 (es) | 1980-11-01 |
FR2462431A1 (fr) | 1981-02-13 |
NL930038I2 (nl) | 1993-10-01 |
NL180420C (nl) | 1987-02-16 |
SE444317B (sv) | 1986-04-07 |
ES8100281A1 (es) | 1980-11-01 |
US4283408A (en) | 1981-08-11 |
JPS5622770A (en) | 1981-03-03 |
IT7969498A0 (it) | 1979-12-28 |
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