JPS56145261A - Novel oxyacetic acid derivative, its preparation, and lowering agent of lipid in blood comprising it as active ingredient - Google Patents
Novel oxyacetic acid derivative, its preparation, and lowering agent of lipid in blood comprising it as active ingredientInfo
- Publication number
- JPS56145261A JPS56145261A JP4624380A JP4624380A JPS56145261A JP S56145261 A JPS56145261 A JP S56145261A JP 4624380 A JP4624380 A JP 4624380A JP 4624380 A JP4624380 A JP 4624380A JP S56145261 A JPS56145261 A JP S56145261A
- Authority
- JP
- Japan
- Prior art keywords
- lipid
- formula
- blood
- acid derivative
- lowering agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/42—Singly bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/54—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4624380A JPS56145261A (en) | 1980-04-10 | 1980-04-10 | Novel oxyacetic acid derivative, its preparation, and lowering agent of lipid in blood comprising it as active ingredient |
GB8107828A GB2073745B (en) | 1980-04-10 | 1981-03-12 | (-benzaminoethylphneoxy) cyclohexyl-acetic acid derivatives compounds |
AU68327/81A AU539457B2 (en) | 1980-04-10 | 1981-03-13 | Benzaminoethyl phenoxycyclohexyl acetic acid |
US06/243,447 US4318923A (en) | 1980-04-10 | 1981-03-13 | Benzaminoethylphenoxycyclohexylacetic acid derivatives |
FR8106553A FR2480279A1 (fr) | 1980-04-10 | 1981-04-01 | Derives d'acides benzaminoethylphenoxycyclohexylacetiques, leur procede de preparation et leur application en therapeutique |
BE0/204399A BE888313A (fr) | 1980-04-10 | 1981-04-07 | Derives d'acides benzamioethylphenoxycyclohexylacetiques, leur procede de preparation et leur application en therapeutique, |
NL8101718A NL8101718A (nl) | 1980-04-10 | 1981-04-08 | Benzaminoethylfenoxycyclohexylazijnzuurderivaten, werkwijze voor het bereiden hiervan, geneesmiddel op basis van dit derivaat. |
DE19813114430 DE3114430A1 (de) | 1980-04-10 | 1981-04-09 | Benzaminoaethylphenoxycyclohexylessigsaeure-derivate, verfahren zur herstellung derselben und arzneimittel mit einem gehalt derselben |
IT21046/81A IT1137454B (it) | 1980-04-10 | 1981-04-10 | Derivati dell'acido benzaminoetilfenossicicloesilacetico |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4624380A JPS56145261A (en) | 1980-04-10 | 1980-04-10 | Novel oxyacetic acid derivative, its preparation, and lowering agent of lipid in blood comprising it as active ingredient |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56145261A true JPS56145261A (en) | 1981-11-11 |
JPS6351143B2 JPS6351143B2 (ja) | 1988-10-13 |
Family
ID=12741696
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP4624380A Granted JPS56145261A (en) | 1980-04-10 | 1980-04-10 | Novel oxyacetic acid derivative, its preparation, and lowering agent of lipid in blood comprising it as active ingredient |
Country Status (9)
Country | Link |
---|---|
US (1) | US4318923A (ja) |
JP (1) | JPS56145261A (ja) |
AU (1) | AU539457B2 (ja) |
BE (1) | BE888313A (ja) |
DE (1) | DE3114430A1 (ja) |
FR (1) | FR2480279A1 (ja) |
GB (1) | GB2073745B (ja) |
IT (1) | IT1137454B (ja) |
NL (1) | NL8101718A (ja) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3729209A1 (de) * | 1987-09-01 | 1989-03-09 | Boehringer Mannheim Gmbh | Verwendung von bezafibrat zur behandlung von diabetes |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR906840A (fr) * | 1943-07-30 | 1946-02-21 | Geigy Ag J R | éthers-sels basiques et amides dérivant d'acides aryl-hydroxy-acétiques alpha-substitués et leur procédé de préparation |
DE2230383C3 (de) * | 1971-10-01 | 1981-12-03 | Boehringer Mannheim Gmbh, 6800 Mannheim | Phenoxyalkylcarbonsäurederivate und Verfahren zur Herstellung derselben |
DE2532420A1 (de) * | 1975-07-19 | 1977-02-03 | Boehringer Mannheim Gmbh | Phenylessigsaeure-derivate und verfahren zu ihrer herstellung |
DE2541342A1 (de) * | 1975-09-17 | 1977-03-31 | Boehringer Mannheim Gmbh | Neue phenoxyalkylcarbonsaeuren und verfahren zur herstellung derselben |
DE2546996C2 (de) * | 1975-10-21 | 1984-07-05 | Boehringer Mannheim Gmbh, 6800 Mannheim | Phenoxyalkylcarbonsäure-Derivate, Verfahren zur Herstellung derselben sowie Arzneimittel, die diese Verbindungen als Wirkstoff enthalten |
US4214094A (en) * | 1977-03-30 | 1980-07-22 | Fujisawa Pharmaceutical Co., Ltd. | Substituted-phenyl substituted-alkyl ethers and the preparation thereof |
-
1980
- 1980-04-10 JP JP4624380A patent/JPS56145261A/ja active Granted
-
1981
- 1981-03-12 GB GB8107828A patent/GB2073745B/en not_active Expired
- 1981-03-13 AU AU68327/81A patent/AU539457B2/en not_active Ceased
- 1981-03-13 US US06/243,447 patent/US4318923A/en not_active Expired - Lifetime
- 1981-04-01 FR FR8106553A patent/FR2480279A1/fr active Granted
- 1981-04-07 BE BE0/204399A patent/BE888313A/fr not_active IP Right Cessation
- 1981-04-08 NL NL8101718A patent/NL8101718A/nl not_active Application Discontinuation
- 1981-04-09 DE DE19813114430 patent/DE3114430A1/de not_active Withdrawn
- 1981-04-10 IT IT21046/81A patent/IT1137454B/it active
Also Published As
Publication number | Publication date |
---|---|
US4318923A (en) | 1982-03-09 |
IT8121046A0 (it) | 1981-04-10 |
IT1137454B (it) | 1986-09-10 |
AU539457B2 (en) | 1984-09-27 |
FR2480279A1 (fr) | 1981-10-16 |
NL8101718A (nl) | 1981-11-02 |
GB2073745A (en) | 1981-10-21 |
AU6832781A (en) | 1981-10-15 |
FR2480279B1 (ja) | 1984-03-09 |
BE888313A (fr) | 1981-10-07 |
DE3114430A1 (de) | 1982-03-11 |
GB2073745B (en) | 1983-10-19 |
JPS6351143B2 (ja) | 1988-10-13 |
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