JPS56140924A - Calcitonin pharmaceutical preparation - Google Patents
Calcitonin pharmaceutical preparationInfo
- Publication number
- JPS56140924A JPS56140924A JP4344080A JP4344080A JPS56140924A JP S56140924 A JPS56140924 A JP S56140924A JP 4344080 A JP4344080 A JP 4344080A JP 4344080 A JP4344080 A JP 4344080A JP S56140924 A JPS56140924 A JP S56140924A
- Authority
- JP
- Japan
- Prior art keywords
- acid
- calcitonin
- pharmaceutical preparation
- absorbed
- sodium salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000055006 Calcitonin Human genes 0.000 title abstract 5
- 108060001064 Calcitonin Proteins 0.000 title abstract 5
- BBBFJLBPOGFECG-VJVYQDLKSA-N calcitonin Chemical compound N([C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(N)=O)C(C)C)C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1 BBBFJLBPOGFECG-VJVYQDLKSA-N 0.000 title abstract 5
- 229960004015 calcitonin Drugs 0.000 title abstract 5
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 3
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 4
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 abstract 3
- 230000001079 digestive effect Effects 0.000 abstract 3
- 230000002378 acidificating effect Effects 0.000 abstract 2
- 235000001014 amino acid Nutrition 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 229960005070 ascorbic acid Drugs 0.000 abstract 2
- 235000010323 ascorbic acid Nutrition 0.000 abstract 2
- 239000011668 ascorbic acid Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 210000000214 mouth Anatomy 0.000 abstract 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 abstract 2
- 159000000000 sodium salts Chemical class 0.000 abstract 2
- OYHQOLUKZRVURQ-NTGFUMLPSA-N (9Z,12Z)-9,10,12,13-tetratritiooctadeca-9,12-dienoic acid Chemical compound C(CCCCCCC\C(=C(/C\C(=C(/CCCCC)\[3H])\[3H])\[3H])\[3H])(=O)O OYHQOLUKZRVURQ-NTGFUMLPSA-N 0.000 abstract 1
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 abstract 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 abstract 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 abstract 1
- 208000009137 Behcet syndrome Diseases 0.000 abstract 1
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 abstract 1
- 208000002682 Hyperkalemia Diseases 0.000 abstract 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000005642 Oleic acid Substances 0.000 abstract 1
- 208000001132 Osteoporosis Diseases 0.000 abstract 1
- 108091005804 Peptidases Proteins 0.000 abstract 1
- 239000004365 Protease Substances 0.000 abstract 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 abstract 1
- 206010039984 Senile osteoporosis Diseases 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 238000000354 decomposition reaction Methods 0.000 abstract 1
- -1 glutamic acid Chemical class 0.000 abstract 1
- 235000013922 glutamic acid Nutrition 0.000 abstract 1
- 239000004220 glutamic acid Substances 0.000 abstract 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 abstract 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 abstract 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 229960004889 salicylic acid Drugs 0.000 abstract 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 abstract 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4344080A JPS56140924A (en) | 1980-04-04 | 1980-04-04 | Calcitonin pharmaceutical preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4344080A JPS56140924A (en) | 1980-04-04 | 1980-04-04 | Calcitonin pharmaceutical preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS56140924A true JPS56140924A (en) | 1981-11-04 |
| JPS6236499B2 JPS6236499B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1987-08-07 |
Family
ID=12663751
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP4344080A Granted JPS56140924A (en) | 1980-04-04 | 1980-04-04 | Calcitonin pharmaceutical preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS56140924A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62195336A (ja) * | 1986-02-21 | 1987-08-28 | Sekisui Chem Co Ltd | カルシトニン製剤 |
| JPS63115822A (ja) * | 1986-11-04 | 1988-05-20 | Teijin Ltd | 生理活性ポリペプチド類の経鼻投与用粉末状組成物 |
| JPS63115820A (ja) * | 1986-10-31 | 1988-05-20 | Teijin Ltd | アスコルビン酸類を含有する経鼻投与用粉末状組成物 |
| JPS63307824A (ja) * | 1987-06-09 | 1988-12-15 | Teisan Seiyaku Kk | 安定化注射用粉末製剤 |
| EP0929270A4 (en) * | 1996-03-15 | 2001-05-16 | Unigene Lab Inc | ORAL PHARMACEUTICAL PRODUCTS WITH PEPTIDES |
| JP2001240558A (ja) * | 2000-02-29 | 2001-09-04 | Nippon Suisan Kaisha Ltd | 多価不飽和脂肪酸を経粘膜吸収促進剤として含有する固形製剤。 |
| KR100593861B1 (ko) * | 2001-09-24 | 2006-06-30 | 한국과학기술원 | 칼시토닌을 함유한 경구투여용 나노입자의 제조방법 |
| JP2007535545A (ja) * | 2004-04-28 | 2007-12-06 | プロキャリア・インコーポレーテッド | 難吸収性薬剤の経口投与のための製剤 |
| WO2008038644A1 (fr) | 2006-09-27 | 2008-04-03 | Asahi Kasei Pharma Corporation | AGENT de prÉvention de l'apparition d'une dystrophie sympatHique rÉflexe aprÈs une attaque |
| US7666446B2 (en) * | 2004-04-28 | 2010-02-23 | Procarrier, Inc. | Oral formulation for delivery of poorly absorbed drugs |
| WO2011062073A1 (ja) | 2009-11-18 | 2011-05-26 | 旭化成ファーマ株式会社 | ヒト変形性膝関節症の予防剤および／または治療剤および／または増悪抑制剤 |
| US8088734B2 (en) | 2003-01-21 | 2012-01-03 | Unigene Laboratories Inc. | Oral delivery of peptides |
-
1980
- 1980-04-04 JP JP4344080A patent/JPS56140924A/ja active Granted
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62195336A (ja) * | 1986-02-21 | 1987-08-28 | Sekisui Chem Co Ltd | カルシトニン製剤 |
| JPS63115820A (ja) * | 1986-10-31 | 1988-05-20 | Teijin Ltd | アスコルビン酸類を含有する経鼻投与用粉末状組成物 |
| JPS63115822A (ja) * | 1986-11-04 | 1988-05-20 | Teijin Ltd | 生理活性ポリペプチド類の経鼻投与用粉末状組成物 |
| JPS63307824A (ja) * | 1987-06-09 | 1988-12-15 | Teisan Seiyaku Kk | 安定化注射用粉末製剤 |
| EP0929270A4 (en) * | 1996-03-15 | 2001-05-16 | Unigene Lab Inc | ORAL PHARMACEUTICAL PRODUCTS WITH PEPTIDES |
| JP2001240558A (ja) * | 2000-02-29 | 2001-09-04 | Nippon Suisan Kaisha Ltd | 多価不飽和脂肪酸を経粘膜吸収促進剤として含有する固形製剤。 |
| KR100593861B1 (ko) * | 2001-09-24 | 2006-06-30 | 한국과학기술원 | 칼시토닌을 함유한 경구투여용 나노입자의 제조방법 |
| US8088734B2 (en) | 2003-01-21 | 2012-01-03 | Unigene Laboratories Inc. | Oral delivery of peptides |
| JP2007535545A (ja) * | 2004-04-28 | 2007-12-06 | プロキャリア・インコーポレーテッド | 難吸収性薬剤の経口投与のための製剤 |
| US7666446B2 (en) * | 2004-04-28 | 2010-02-23 | Procarrier, Inc. | Oral formulation for delivery of poorly absorbed drugs |
| AU2005237580B2 (en) * | 2004-04-28 | 2011-06-16 | Procarrier, Inc. | Oral formulation for delivery of poorly absorbed drugs |
| WO2008038644A1 (fr) | 2006-09-27 | 2008-04-03 | Asahi Kasei Pharma Corporation | AGENT de prÉvention de l'apparition d'une dystrophie sympatHique rÉflexe aprÈs une attaque |
| WO2011062073A1 (ja) | 2009-11-18 | 2011-05-26 | 旭化成ファーマ株式会社 | ヒト変形性膝関節症の予防剤および／または治療剤および／または増悪抑制剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6236499B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1987-08-07 |
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