JPS56135489A - Preparative method of cephalosporanic acid derivative - Google Patents

Preparative method of cephalosporanic acid derivative

Info

Publication number
JPS56135489A
JPS56135489A JP3750180A JP3750180A JPS56135489A JP S56135489 A JPS56135489 A JP S56135489A JP 3750180 A JP3750180 A JP 3750180A JP 3750180 A JP3750180 A JP 3750180A JP S56135489 A JPS56135489 A JP S56135489A
Authority
JP
Japan
Prior art keywords
derivative
acid derivative
formula
cephalosporanic acid
pyridine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP3750180A
Other languages
Japanese (ja)
Inventor
Masahiro Murakami
Masateru Kobayashi
Kimiyo Yamamoto
Kazuyuki Shibuya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Chemical Industry Co Ltd
Original Assignee
Asahi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Chemical Industry Co Ltd filed Critical Asahi Chemical Industry Co Ltd
Priority to JP3750180A priority Critical patent/JPS56135489A/en
Publication of JPS56135489A publication Critical patent/JPS56135489A/en
Pending legal-status Critical Current

Links

Abstract

PURPOSE: A 7-aminocephalosporanic acid derivative is made to react with a novel active ester to safely produce the titled derivative used as antibiotic against grampositive and -negative bacteria in high yield.
CONSTITUTION: The reaction between a 7-aminocephalosporanic acid derivative or its salt of formula I (R is halogen, azide, acetoxy) and mandelic pyridine-N-oxide- 2-yl thiol ester is conducted, preferably at a molar ratio of 1:(1W2) in a solvent of DMF at 40°W80°C to produce the objective cephalosporanic acid derivative of formula III. The compound of formula II is novel and obtained, e.g., by reaction of pyridine-N-oxide-2-thiol of formula IV or its derivative with madelic acid or its derivative in a solvent at -50°W+100°C.
COPYRIGHT: (C)1981,JPO&Japio
JP3750180A 1980-03-26 1980-03-26 Preparative method of cephalosporanic acid derivative Pending JPS56135489A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP3750180A JPS56135489A (en) 1980-03-26 1980-03-26 Preparative method of cephalosporanic acid derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3750180A JPS56135489A (en) 1980-03-26 1980-03-26 Preparative method of cephalosporanic acid derivative

Publications (1)

Publication Number Publication Date
JPS56135489A true JPS56135489A (en) 1981-10-22

Family

ID=12499266

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3750180A Pending JPS56135489A (en) 1980-03-26 1980-03-26 Preparative method of cephalosporanic acid derivative

Country Status (1)

Country Link
JP (1) JPS56135489A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210371192A1 (en) * 2018-10-02 2021-12-02 Jung Han CHAE Ice cream packaging material using horizontal disposable plastic film mold as inner packaging material

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210371192A1 (en) * 2018-10-02 2021-12-02 Jung Han CHAE Ice cream packaging material using horizontal disposable plastic film mold as inner packaging material

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