JPS5583774A - N-substituted trimethoxybenzylpiperazine derivative and its acid addition salt - Google Patents
N-substituted trimethoxybenzylpiperazine derivative and its acid addition saltInfo
- Publication number
- JPS5583774A JPS5583774A JP15829378A JP15829378A JPS5583774A JP S5583774 A JPS5583774 A JP S5583774A JP 15829378 A JP15829378 A JP 15829378A JP 15829378 A JP15829378 A JP 15829378A JP S5583774 A JPS5583774 A JP S5583774A
- Authority
- JP
- Japan
- Prior art keywords
- addition salt
- acid addition
- trimethoxybenzylpiperazine
- derivative
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A compound of formula I or its acid addition salt (R1W5 are H, lower alkyl, lower alkoxy, nitro, halogen, or CF3; X is methylene, propylene, or ethenylene).
EXAMPLE: 1-(2,3,4-Trimethoxybenzyl)-4-(3-phenylpropionyl)piperazine.
USE: A low-toxic drug having coronary vessel blood flow increasing, calcium antagonistic activity. Stronger activity than trimethazidine.
PROCESS: A compound I is prepared by acylating trimethazidine with a carboxylic acid II or its acid halide.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15829378A JPS5583774A (en) | 1978-12-20 | 1978-12-20 | N-substituted trimethoxybenzylpiperazine derivative and its acid addition salt |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15829378A JPS5583774A (en) | 1978-12-20 | 1978-12-20 | N-substituted trimethoxybenzylpiperazine derivative and its acid addition salt |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5583774A true JPS5583774A (en) | 1980-06-24 |
Family
ID=15668433
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP15829378A Pending JPS5583774A (en) | 1978-12-20 | 1978-12-20 | N-substituted trimethoxybenzylpiperazine derivative and its acid addition salt |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5583774A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0344577A2 (en) * | 1988-06-01 | 1989-12-06 | Eisai Co., Ltd. | Butenoic or propenoic acid derivatives |
-
1978
- 1978-12-20 JP JP15829378A patent/JPS5583774A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0344577A2 (en) * | 1988-06-01 | 1989-12-06 | Eisai Co., Ltd. | Butenoic or propenoic acid derivatives |
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