JPS5520800A - Cephem compounds, their salts, their preparation, and preventive or remedy for microbism containing the same as the effective component - Google Patents
Cephem compounds, their salts, their preparation, and preventive or remedy for microbism containing the same as the effective componentInfo
- Publication number
- JPS5520800A JPS5520800A JP9831679A JP9831679A JPS5520800A JP S5520800 A JPS5520800 A JP S5520800A JP 9831679 A JP9831679 A JP 9831679A JP 9831679 A JP9831679 A JP 9831679A JP S5520800 A JPS5520800 A JP S5520800A
- Authority
- JP
- Japan
- Prior art keywords
- salts
- preparation
- amino
- microbism
- remedy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB7831694 | 1978-07-31 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP61179722A Division JPS6263578A (ja) | 1978-07-31 | 1986-07-30 | アミノチアゾリル酢酸誘導体 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5520800A true JPS5520800A (en) | 1980-02-14 |
JPH0127076B2 JPH0127076B2 (ja) | 1989-05-26 |
Family
ID=10498766
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP9831679A Granted JPS5520800A (en) | 1978-07-31 | 1979-07-31 | Cephem compounds, their salts, their preparation, and preventive or remedy for microbism containing the same as the effective component |
JP61179722A Granted JPS6263578A (ja) | 1978-07-31 | 1986-07-30 | アミノチアゾリル酢酸誘導体 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP61179722A Granted JPS6263578A (ja) | 1978-07-31 | 1986-07-30 | アミノチアゾリル酢酸誘導体 |
Country Status (4)
Country | Link |
---|---|
US (2) | US4284631A (ja) |
EP (2) | EP0049539B1 (ja) |
JP (2) | JPS5520800A (ja) |
DE (1) | DE2966913D1 (ja) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57154190A (en) * | 1980-12-22 | 1982-09-22 | Fujisawa Pharmaceut Co Ltd | 7-substituted cephalosporanic acid derivative and its preparation |
JPS5849382A (ja) * | 1981-09-18 | 1983-03-23 | Kyowa Hakko Kogyo Co Ltd | β−ラクタム化合物 |
JPS5874680A (ja) * | 1981-10-01 | 1983-05-06 | Kyowa Hakko Kogyo Co Ltd | β−ラクタム化合物 |
JPH06323711A (ja) * | 1993-04-28 | 1994-11-25 | Nec Corp | 電源ユニット冷却構造 |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4427674A (en) | 1977-03-14 | 1984-01-24 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
US4393059A (en) * | 1977-03-14 | 1983-07-12 | Fujisawa Pharmaceutical Company, Limited | Cephem compounds |
PH17188A (en) * | 1977-03-14 | 1984-06-14 | Fujisawa Pharmaceutical Co | New cephem and cepham compounds and their pharmaceutical compositions and method of use |
US4400379A (en) * | 1977-03-14 | 1983-08-23 | Fujisawa Pharmaceutical Company, Limited | Cephem compounds |
SE448379B (sv) * | 1978-03-31 | 1987-02-16 | Roussel Uclaf | O-substituerade oximderivat av 7-amino-tiazolyl-acetamidocefalosporansyra |
FR2432521A1 (fr) * | 1978-03-31 | 1980-02-29 | Roussel Uclaf | Nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
US4372952A (en) * | 1978-07-31 | 1983-02-08 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
FR2453161A1 (fr) * | 1978-08-31 | 1980-10-31 | Fujisawa Pharmaceutical Co | Procede de preparation de derives d'acide thiazolylacetique et nouveaux produits ainsi obtenus |
US4409214A (en) * | 1979-11-19 | 1983-10-11 | Fujisawa Pharmaceutical, Co., Ltd. | 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof |
US4416879A (en) * | 1980-09-08 | 1983-11-22 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
PH19163A (en) * | 1982-04-06 | 1986-01-16 | Daiichi Seiyaku Co | Cephalosporin derivatives |
IE55406B1 (en) * | 1982-08-07 | 1990-09-12 | Tanabe Seiyaku Co | Novel cephalosporin compounds and preparation thereof |
EP0210815A3 (en) * | 1985-07-25 | 1988-04-20 | Beecham Group Plc | 6-beta-(alpha-etherified oxyimino)-acylamino penicillanic-acid derivatives, their preparation and use |
EP0400805A1 (en) * | 1989-04-25 | 1990-12-05 | Toshiyasu Ishimaru | Cephalosporin compounds and their use |
TWI335332B (en) * | 2001-10-12 | 2011-01-01 | Theravance Inc | Cross-linked vancomycin-cephalosporin antibiotics |
EP3616695A1 (en) | 2011-09-09 | 2020-03-04 | Merck Sharp & Dohme Corp. | Methods for treating intrapulmonary infections |
US8809314B1 (en) | 2012-09-07 | 2014-08-19 | Cubist Pharmacueticals, Inc. | Cephalosporin compound |
US8476425B1 (en) | 2012-09-27 | 2013-07-02 | Cubist Pharmaceuticals, Inc. | Tazobactam arginine compositions |
AU2014249611B2 (en) | 2013-03-13 | 2017-12-21 | Theravance Biopharma Antibiotics Ip, Llc | Crystalline form of a substituted thiazolylacetic acid triethylamine salt |
KR102329764B1 (ko) | 2013-03-15 | 2021-11-23 | 머크 샤프 앤드 돔 코포레이션 | 세프톨로잔 항균성 조성물 |
US9872906B2 (en) | 2013-03-15 | 2018-01-23 | Merck Sharp & Dohme Corp. | Ceftolozane antibiotic compositions |
US20140274991A1 (en) | 2013-03-15 | 2014-09-18 | Cubist Pharmaceuticals, Inc. | Ceftolozane pharmaceutical compositions |
EP3043797B1 (en) | 2013-09-09 | 2020-04-08 | Merck Sharp & Dohme Corp. | Treating infections with ceftolozane/tazobactam in subjects having impaired renal function |
US20150094293A1 (en) | 2013-09-27 | 2015-04-02 | Calixa Therapeutics, Inc. | Solid forms of ceftolozane |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5328141A (en) * | 1971-05-14 | 1978-03-16 | Glaxo Lab Ltd | Production of novel carboxylic acid |
JPS549296A (en) * | 1977-04-02 | 1979-01-24 | Hoechst Ag | Cephem derivative and its preparation |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1496757A (en) * | 1973-12-21 | 1978-01-05 | Glaxo Lab Ltd | Cephalosporin derivatives |
US4020058A (en) * | 1974-10-03 | 1977-04-26 | Glaxo Laboratories Limited | Improvements in or relating to cephalosporin antibiotics |
DK154939C (da) * | 1974-12-19 | 1989-06-12 | Takeda Chemical Industries Ltd | Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf |
GB1555471A (en) * | 1975-06-19 | 1979-11-14 | Glaxo Lab Ltd | 7 carbamoylalkoxyimino acetamido 3 em 4 carboxylic acidsand derivatives thereof |
DE2760123C2 (de) * | 1976-01-23 | 1986-04-30 | Roussel-Uclaf, Paris | 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen |
SE440655B (sv) * | 1976-01-23 | 1985-08-12 | Roussel Uclaf | Sett att framstella nya oximderivat av 7-amino-tiazolyl-acetamido-cefalosporansyra |
US4166115A (en) * | 1976-04-12 | 1979-08-28 | Fujisawa Pharmaceutical Co., Ltd. | Syn 7-oxoimino substituted derivatives of cephalosporanic acid |
DK162391C (da) * | 1976-04-12 | 1992-03-09 | Fujisawa Pharmaceutical Co | Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser |
JPS53103493A (en) | 1977-02-18 | 1978-09-08 | Takeda Chem Ind Ltd | Cephalosporin derivatives and process for their preparation |
PH17188A (en) * | 1977-03-14 | 1984-06-14 | Fujisawa Pharmaceutical Co | New cephem and cepham compounds and their pharmaceutical compositions and method of use |
FR2384779A1 (fr) | 1977-03-25 | 1978-10-20 | Roussel Uclaf | Nouvelles oximes derivees de l'acide 3-chloro ou 3-methoxy 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
SE439312B (sv) * | 1977-03-25 | 1985-06-10 | Roussel Uclaf | Sett att framstella nya oximderivat av 3-acetoximetyl-7-aminotiazolylacetamido cefalosporansyra |
US4370326A (en) * | 1977-09-13 | 1983-01-25 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds and composition |
FR2410655A1 (fr) * | 1977-12-05 | 1979-06-29 | Roussel Uclaf | Nouvelles oximes derivees de l'acide 3-substitue 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
FR2432521A1 (fr) * | 1978-03-31 | 1980-02-29 | Roussel Uclaf | Nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
FR2421907A1 (fr) * | 1978-04-07 | 1979-11-02 | Roussel Uclaf | Nouvelles cephalosporines derivees de l'acide 7-/2-(2-amino 4-thiazolyl)2-(carboxymethoxyimino/acetamido 3-substitue cephalosporanique, leur procede de preparation et leur application comme medicaments |
FR2422668A1 (fr) * | 1978-04-14 | 1979-11-09 | Roussel Uclaf | Nouvelles oximes derivees de l'acide 3-azidomethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
-
1979
- 1979-07-23 US US06/059,893 patent/US4284631A/en not_active Expired - Lifetime
- 1979-07-26 EP EP81110041A patent/EP0049539B1/en not_active Expired
- 1979-07-26 DE DE7979102664T patent/DE2966913D1/de not_active Expired
- 1979-07-26 EP EP79102664A patent/EP0007633B1/en not_active Expired
- 1979-07-31 JP JP9831679A patent/JPS5520800A/ja active Granted
-
1984
- 1984-12-03 US US06/676,608 patent/US4598147A/en not_active Expired - Fee Related
-
1986
- 1986-07-30 JP JP61179722A patent/JPS6263578A/ja active Granted
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5328141A (en) * | 1971-05-14 | 1978-03-16 | Glaxo Lab Ltd | Production of novel carboxylic acid |
JPS549296A (en) * | 1977-04-02 | 1979-01-24 | Hoechst Ag | Cephem derivative and its preparation |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57154190A (en) * | 1980-12-22 | 1982-09-22 | Fujisawa Pharmaceut Co Ltd | 7-substituted cephalosporanic acid derivative and its preparation |
JPS5849382A (ja) * | 1981-09-18 | 1983-03-23 | Kyowa Hakko Kogyo Co Ltd | β−ラクタム化合物 |
JPS5874680A (ja) * | 1981-10-01 | 1983-05-06 | Kyowa Hakko Kogyo Co Ltd | β−ラクタム化合物 |
JPH06323711A (ja) * | 1993-04-28 | 1994-11-25 | Nec Corp | 電源ユニット冷却構造 |
Also Published As
Publication number | Publication date |
---|---|
US4598147A (en) | 1986-07-01 |
EP0007633A3 (en) | 1980-06-25 |
EP0007633B1 (en) | 1984-04-18 |
JPS6263578A (ja) | 1987-03-20 |
JPH0127076B2 (ja) | 1989-05-26 |
JPH0333154B2 (ja) | 1991-05-16 |
EP0007633A2 (en) | 1980-02-06 |
US4284631A (en) | 1981-08-18 |
DE2966913D1 (en) | 1984-05-24 |
EP0049539A1 (en) | 1982-04-14 |
EP0049539B1 (en) | 1985-10-16 |
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