JPS55147246A - Preparation of alpha-chloro-beta-alanine - Google Patents
Preparation of alpha-chloro-beta-alanineInfo
- Publication number
- JPS55147246A JPS55147246A JP5471179A JP5471179A JPS55147246A JP S55147246 A JPS55147246 A JP S55147246A JP 5471179 A JP5471179 A JP 5471179A JP 5471179 A JP5471179 A JP 5471179A JP S55147246 A JPS55147246 A JP S55147246A
- Authority
- JP
- Japan
- Prior art keywords
- chloro
- mineral acid
- phthalimidopropionitrile
- alanine
- beta
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: To obtain the title compound which is useful as an intermediate for α- amino acids such as serine, medicines, etc., in high yield, by hydrolyzing α-chloro- β-phthalimidopropionitrile.
CONSTITUTION: The title compound is obtained rapidly and easily by adding α-chloro-β-phthalimidopropionitrile to a mineral acid, pref. raising the temperature while stirring, and reacting at 50W150°C for 2W15hr. The reaction solution is subjected to thin-layer chromatography. The mineral acid is, e.g. hydrochloric acid, sulfuric acid, etc. Concentration of the mineral acid is selected appropriately in the range of 3W80wt%. Suitably in reaction operations, the amount of the mineral acid used is usually at least 2pts.wt. preferably at least 3pts.wt. to 1pt.wt. of α-chloro- β-phthalimidopropionitrile.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5471179A JPS55147246A (en) | 1979-05-07 | 1979-05-07 | Preparation of alpha-chloro-beta-alanine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5471179A JPS55147246A (en) | 1979-05-07 | 1979-05-07 | Preparation of alpha-chloro-beta-alanine |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS55147246A true JPS55147246A (en) | 1980-11-17 |
JPS6157823B2 JPS6157823B2 (en) | 1986-12-09 |
Family
ID=12978379
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP5471179A Granted JPS55147246A (en) | 1979-05-07 | 1979-05-07 | Preparation of alpha-chloro-beta-alanine |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55147246A (en) |
-
1979
- 1979-05-07 JP JP5471179A patent/JPS55147246A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS6157823B2 (en) | 1986-12-09 |
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