JPS55145695A - Novel mixed acid anhydride - Google Patents
Novel mixed acid anhydrideInfo
- Publication number
- JPS55145695A JPS55145695A JP5319379A JP5319379A JPS55145695A JP S55145695 A JPS55145695 A JP S55145695A JP 5319379 A JP5319379 A JP 5319379A JP 5319379 A JP5319379 A JP 5319379A JP S55145695 A JPS55145695 A JP S55145695A
- Authority
- JP
- Japan
- Prior art keywords
- amino
- acid anhydride
- group
- mixed acid
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
NEW MATERIAL:A mixed acid anhydride of formula [R1 and R2 are (substituted) alkyl, (substituted)aryl, or may be a cyclic arakyl group, and either of R1 and R2 may be a resin; a is amino-protecting group; A is amino acid redidue or amino acid derivative residue after removal of H from the amino group and H from the carboxyl group, or peptide residue].
EXAMPLE: Mixed diphenylphosphinothioyl-L-proline diphenylthiophosphinic acid anhydride.
USE: An intermediate for the synthesis of peptide.
PROCESS: An amino-protecting group is reacted with a halogenated phosphinothioyl compound or resin in a solvent, e.g. dioxane, in the presence of an amine, preferably dicyclohexylamine, at room temperature to give the title anhydride.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5319379A JPS55145695A (en) | 1979-04-28 | 1979-04-28 | Novel mixed acid anhydride |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5319379A JPS55145695A (en) | 1979-04-28 | 1979-04-28 | Novel mixed acid anhydride |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS55145695A true JPS55145695A (en) | 1980-11-13 |
Family
ID=12936028
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP5319379A Pending JPS55145695A (en) | 1979-04-28 | 1979-04-28 | Novel mixed acid anhydride |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55145695A (en) |
-
1979
- 1979-04-28 JP JP5319379A patent/JPS55145695A/en active Pending
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