JPS5513221A - 3-ethylidene phthalide derivative and its preparation - Google Patents
3-ethylidene phthalide derivative and its preparationInfo
- Publication number
- JPS5513221A JPS5513221A JP8581478A JP8581478A JPS5513221A JP S5513221 A JPS5513221 A JP S5513221A JP 8581478 A JP8581478 A JP 8581478A JP 8581478 A JP8581478 A JP 8581478A JP S5513221 A JPS5513221 A JP S5513221A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound shown
- preparation
- halogen
- penicillin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- FLOWXWKOKRXGBR-UHFFFAOYSA-N 3-ethylidene-2-benzofuran-1-one Chemical class C1=CC=C2C(=CC)OC(=O)C2=C1 FLOWXWKOKRXGBR-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 abstract 2
- 229930182555 Penicillin Natural products 0.000 abstract 2
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 229940049954 penicillin Drugs 0.000 abstract 2
- OZAIFHULBGXAKX-UHFFFAOYSA-N 2-(2-cyanopropan-2-yldiazenyl)-2-methylpropanenitrile Chemical compound N#CC(C)(C)N=NC(C)(C)C#N OZAIFHULBGXAKX-UHFFFAOYSA-N 0.000 abstract 1
- XLDBFJIFFFXPHV-UHFFFAOYSA-N 3-(2-bromoethylidene)-2-benzofuran-1-one Chemical compound C1=CC=C2C(=CCBr)OC(=O)C2=C1 XLDBFJIFFFXPHV-UHFFFAOYSA-N 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 125000002843 carboxylic acid group Chemical group 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 230000026030 halogenation Effects 0.000 abstract 1
- 238000005658 halogenation reaction Methods 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 150000003949 imides Chemical class 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000003607 modifier Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- IOVGROKTTNBUGK-SJCJKPOMSA-N ritodrine Chemical compound N([C@@H](C)[C@H](O)C=1C=CC(O)=CC=1)CCC1=CC=C(O)C=C1 IOVGROKTTNBUGK-SJCJKPOMSA-N 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Furan Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8581478A JPS5513221A (en) | 1978-07-13 | 1978-07-13 | 3-ethylidene phthalide derivative and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8581478A JPS5513221A (en) | 1978-07-13 | 1978-07-13 | 3-ethylidene phthalide derivative and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5513221A true JPS5513221A (en) | 1980-01-30 |
| JPS626552B2 JPS626552B2 (enrdf_load_stackoverflow) | 1987-02-12 |
Family
ID=13869321
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP8581478A Granted JPS5513221A (en) | 1978-07-13 | 1978-07-13 | 3-ethylidene phthalide derivative and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5513221A (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5921692A (ja) * | 1982-07-29 | 1984-02-03 | Sankyo Co Ltd | 経口ペネム化合物及びその製法 |
| JPS63231880A (ja) * | 1987-03-18 | 1988-09-27 | Yuasa Battery Co Ltd | 鉛蓄電池の充電制御方式 |
-
1978
- 1978-07-13 JP JP8581478A patent/JPS5513221A/ja active Granted
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5921692A (ja) * | 1982-07-29 | 1984-02-03 | Sankyo Co Ltd | 経口ペネム化合物及びその製法 |
| JPS63231880A (ja) * | 1987-03-18 | 1988-09-27 | Yuasa Battery Co Ltd | 鉛蓄電池の充電制御方式 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS626552B2 (enrdf_load_stackoverflow) | 1987-02-12 |
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