JPS55124760A - Preparation of 1,4-dihydropyridine derivative or its salt - Google Patents
Preparation of 1,4-dihydropyridine derivative or its saltInfo
- Publication number
- JPS55124760A JPS55124760A JP3152179A JP3152179A JPS55124760A JP S55124760 A JPS55124760 A JP S55124760A JP 3152179 A JP3152179 A JP 3152179A JP 3152179 A JP3152179 A JP 3152179A JP S55124760 A JPS55124760 A JP S55124760A
- Authority
- JP
- Japan
- Prior art keywords
- ammonium
- formula
- aldehyde
- carbonate
- compound shown
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- YNGDWRXWKFWCJY-UHFFFAOYSA-N 1,4-Dihydropyridine Chemical class C1C=CNC=C1 YNGDWRXWKFWCJY-UHFFFAOYSA-N 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- ATRRKUHOCOJYRX-UHFFFAOYSA-N Ammonium bicarbonate Chemical compound [NH4+].OC([O-])=O ATRRKUHOCOJYRX-UHFFFAOYSA-N 0.000 abstract 4
- 239000001099 ammonium carbonate Substances 0.000 abstract 3
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 3
- 229910000013 Ammonium bicarbonate Inorganic materials 0.000 abstract 2
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 235000012538 ammonium bicarbonate Nutrition 0.000 abstract 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 235000012501 ammonium carbonate Nutrition 0.000 abstract 1
- 239000007810 chemical reaction solvent Substances 0.000 abstract 1
- 239000012046 mixed solvent Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 1
- 229940124549 vasodilator Drugs 0.000 abstract 1
- 239000003071 vasodilator agent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3152179A JPS55124760A (en) | 1979-03-16 | 1979-03-16 | Preparation of 1,4-dihydropyridine derivative or its salt |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3152179A JPS55124760A (en) | 1979-03-16 | 1979-03-16 | Preparation of 1,4-dihydropyridine derivative or its salt |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS55124760A true JPS55124760A (en) | 1980-09-26 |
| JPS5730104B2 JPS5730104B2 (enExample) | 1982-06-26 |
Family
ID=12333488
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP3152179A Granted JPS55124760A (en) | 1979-03-16 | 1979-03-16 | Preparation of 1,4-dihydropyridine derivative or its salt |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS55124760A (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT380876B (de) * | 1981-08-19 | 1986-07-25 | Lek Tovarna Farmacevtskih | Verfahren zur herstellung von 4-(2'-nitrophenyl)2,6-dimethyl-3,5-dimethoxycarbonyl-1,4 -dihydropyridin |
| CN102382040A (zh) * | 2010-09-02 | 2012-03-21 | 常州市第四制药厂有限公司 | 硝苯地平的制备及其杂质分离方法与应用 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1173862A (en) * | 1967-03-20 | 1969-12-10 | Bayer Ag | 4-Aryl-1,4-Dihydropyridine Derivatives and their production |
-
1979
- 1979-03-16 JP JP3152179A patent/JPS55124760A/ja active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1173862A (en) * | 1967-03-20 | 1969-12-10 | Bayer Ag | 4-Aryl-1,4-Dihydropyridine Derivatives and their production |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT380876B (de) * | 1981-08-19 | 1986-07-25 | Lek Tovarna Farmacevtskih | Verfahren zur herstellung von 4-(2'-nitrophenyl)2,6-dimethyl-3,5-dimethoxycarbonyl-1,4 -dihydropyridin |
| CN102382040A (zh) * | 2010-09-02 | 2012-03-21 | 常州市第四制药厂有限公司 | 硝苯地平的制备及其杂质分离方法与应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5730104B2 (enExample) | 1982-06-26 |
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