JPS5430146A - Novel anthracycline derivatives and their preparation - Google Patents

Novel anthracycline derivatives and their preparation

Info

Publication number
JPS5430146A
JPS5430146A JP9434877A JP9434877A JPS5430146A JP S5430146 A JPS5430146 A JP S5430146A JP 9434877 A JP9434877 A JP 9434877A JP 9434877 A JP9434877 A JP 9434877A JP S5430146 A JPS5430146 A JP S5430146A
Authority
JP
Japan
Prior art keywords
preparation
anthracycline derivatives
novel anthracycline
group
hydroxyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP9434877A
Other languages
English (en)
Other versions
JPS5647194B2 (ja
Inventor
Hamao Umezawa
Tomio Takeuchi
Hiroshi Osanawa
Kuniaki Tatsuta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Priority to JP9434877A priority Critical patent/JPS5430146A/ja
Priority to ZA00784033A priority patent/ZA784033B/xx
Priority to GR56794A priority patent/GR63951B/el
Priority to DE2831579A priority patent/DE2831579C3/de
Priority to NLAANVRAGE7807906,A priority patent/NL174147C/xx
Priority to GB7831324A priority patent/GB2002754B/en
Priority to AU38446/78A priority patent/AU510946B2/en
Priority to BE189604A priority patent/BE869395A/xx
Priority to SE7808304A priority patent/SE443565B/sv
Priority to CA000308532A priority patent/CA1120925A/en
Priority to IE1566/78A priority patent/IE47252B1/en
Priority to DK343878A priority patent/DK152677C/da
Priority to FI782388A priority patent/FI63420C/fi
Priority to FR7822859A priority patent/FR2399439A1/fr
Priority to ES472306A priority patent/ES472306A1/es
Priority to AT561278A priority patent/AT361622B/de
Priority to IT68847/78A priority patent/IT1160574B/it
Publication of JPS5430146A publication Critical patent/JPS5430146A/ja
Publication of JPS5647194B2 publication Critical patent/JPS5647194B2/ja
Priority to SG53/83A priority patent/SG5383G/en
Priority to HK186/83A priority patent/HK18683A/xx
Priority to DK093286A priority patent/DK153491C/da
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP9434877A 1977-08-05 1977-08-05 Novel anthracycline derivatives and their preparation Granted JPS5430146A (en)

Priority Applications (20)

Application Number Priority Date Filing Date Title
JP9434877A JPS5430146A (en) 1977-08-05 1977-08-05 Novel anthracycline derivatives and their preparation
ZA00784033A ZA784033B (en) 1977-08-05 1978-07-14 New antitumor anthracycline antibiotics
GR56794A GR63951B (en) 1977-08-05 1978-07-15 New antibiotics of carboncycline against tumours
DE2831579A DE2831579C3 (de) 1977-08-05 1978-07-18 Tetrahydropyranylether von Daunomycin und Adriamycin, Verfahren zu ihrer Herstellung, sowie diese Verbindungen enthaltende pharmazeutische Zubereitungen
NLAANVRAGE7807906,A NL174147C (nl) 1977-08-05 1978-07-26 Werkwijze ter bereiding of vervaardiging van een geneesmiddel met een werking tegen tumor en met een anti-microbiele activiteit, alsmede een anthracyclineglycoside.
GB7831324A GB2002754B (en) 1977-08-05 1978-07-27 Antitumor anthracycline antibiotics
AU38446/78A AU510946B2 (en) 1977-08-05 1978-07-28 Anthracycline glycoside antibiotics
BE189604A BE869395A (fr) 1977-08-05 1978-07-31 Procede de production de nouveaux derives d'anthracycline
SE7808304A SE443565B (sv) 1977-08-05 1978-08-01 Tetrahydropyranylderivat av antracyklinglykosider
CA000308532A CA1120925A (en) 1977-08-05 1978-08-01 Antitumor anthracycline antibiotics
IE1566/78A IE47252B1 (en) 1977-08-05 1978-08-01 Antitumor anthracycline antibiotics
DK343878A DK152677C (da) 1977-08-05 1978-08-02 Analogifremgangsmaade til fremstilling af 4'-0-tetra-hydropyranyladriamycin eller et ugiftigt syreadditionssalt deraf
FI782388A FI63420C (fi) 1977-08-05 1978-08-02 Foerfarande foer framstaellning av terapeutiskt verksamma tetrahydropyranylderivat av antracyklinglykosider
FR7822859A FR2399439A1 (fr) 1977-08-05 1978-08-02 Anthracyclines antibiotiques contre les tumeurs
ES472306A ES472306A1 (es) 1977-08-05 1978-08-02 Un procedimiento para la produccion de un glicosido de an- traciclina
AT561278A AT361622B (de) 1977-08-05 1978-08-02 Verfahren zur herstellung von neuen anthra- cyclinglycosid-anitbiotika
IT68847/78A IT1160574B (it) 1977-08-05 1978-08-03 Antibiotici antitumorali antraciclinici
SG53/83A SG5383G (en) 1977-08-05 1983-02-05 Antitumor anthracycline antibiotics
HK186/83A HK18683A (en) 1977-08-05 1983-06-02 Antitumor anthracycline antibiotics
DK093286A DK153491C (da) 1977-08-05 1986-02-28 Analogifremgangsmaade til fremstilling af et 4'-0-tetrahydropyranyl- eller 4',14-bis(0-tetrahydropyranyl)-anthracyclinglycosid eller et ugiftigt syreadditionssalt deraf

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9434877A JPS5430146A (en) 1977-08-05 1977-08-05 Novel anthracycline derivatives and their preparation

Publications (2)

Publication Number Publication Date
JPS5430146A true JPS5430146A (en) 1979-03-06
JPS5647194B2 JPS5647194B2 (ja) 1981-11-07

Family

ID=14107771

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9434877A Granted JPS5430146A (en) 1977-08-05 1977-08-05 Novel anthracycline derivatives and their preparation

Country Status (19)

Country Link
JP (1) JPS5430146A (ja)
AT (1) AT361622B (ja)
AU (1) AU510946B2 (ja)
BE (1) BE869395A (ja)
CA (1) CA1120925A (ja)
DE (1) DE2831579C3 (ja)
DK (1) DK152677C (ja)
ES (1) ES472306A1 (ja)
FI (1) FI63420C (ja)
FR (1) FR2399439A1 (ja)
GB (1) GB2002754B (ja)
GR (1) GR63951B (ja)
HK (1) HK18683A (ja)
IE (1) IE47252B1 (ja)
IT (1) IT1160574B (ja)
NL (1) NL174147C (ja)
SE (1) SE443565B (ja)
SG (1) SG5383G (ja)
ZA (1) ZA784033B (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100398289B1 (ko) * 1998-05-07 2003-09-19 박상철 신규 안트라사이클린 유도체 및 그 제조방법

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK160616C (da) * 1979-02-03 1991-09-02 Zaidan Hojin Biseibutsu Fremgangsmaade til fremstilling af anthracyclinderivater eller syreadditionssalte deraf
JPS56156300A (en) * 1980-04-26 1981-12-02 Microbial Chem Res Found Novel preparative method of anthracyclin derivative
JPS6016998A (ja) * 1983-07-07 1985-01-28 Microbial Chem Res Found アントラサイクリン誘導体の製造方法
JPS6083171U (ja) * 1983-11-15 1985-06-08 タキゲン製造株式会社 蝶番
JPS63227599A (ja) * 1987-03-14 1988-09-21 Kirin Brewery Co Ltd アンスラサイクリン化合物およびその用途
DE19544532C2 (de) * 1995-11-29 1997-12-11 Pharma Dynamics Gmbh Verfahren zum Herstellen eines Doxorubicin-Lyophilisats
GB2530001B (en) 2014-06-17 2019-01-16 Gw Pharma Ltd Use of cannabidiol in the reduction of convulsive seizure frequency in treatment-resistant epilepsy
GB201806953D0 (en) 2018-04-27 2018-06-13 Gw Res Ltd Cannabidiol Preparations

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100398289B1 (ko) * 1998-05-07 2003-09-19 박상철 신규 안트라사이클린 유도체 및 그 제조방법

Also Published As

Publication number Publication date
DK152677C (da) 1988-10-24
FR2399439B1 (ja) 1981-07-17
AU510946B2 (en) 1980-07-24
GB2002754B (en) 1982-02-10
IE781566L (en) 1979-02-05
NL174147B (nl) 1983-12-01
ZA784033B (en) 1979-07-25
SG5383G (en) 1983-09-09
AT361622B (de) 1981-03-25
IE47252B1 (en) 1984-02-08
IT1160574B (it) 1987-03-11
DE2831579C3 (de) 1980-09-18
AU3844678A (en) 1980-01-31
SE443565B (sv) 1986-03-03
JPS5647194B2 (ja) 1981-11-07
FI782388A (fi) 1979-02-06
DE2831579B2 (de) 1980-01-24
GB2002754A (en) 1979-02-28
NL7807906A (nl) 1979-02-07
DK152677B (da) 1988-04-11
CA1120925A (en) 1982-03-30
BE869395A (fr) 1978-11-16
FR2399439A1 (fr) 1979-03-02
ES472306A1 (es) 1979-10-01
GR63951B (en) 1980-01-16
FI63420C (fi) 1983-06-10
DE2831579A1 (de) 1979-02-15
HK18683A (en) 1983-06-10
FI63420B (fi) 1983-02-28
DK343878A (da) 1979-02-06
ATA561278A (de) 1980-08-15
NL174147C (nl) 1984-05-01
IT7868847A0 (it) 1978-08-03
SE7808304L (sv) 1979-02-06

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