GB2002754A - Antitumor anthracycline antibiotics - Google Patents

Antitumor anthracycline antibiotics

Info

Publication number
GB2002754A
GB2002754A GB7831324A GB7831324A GB2002754A GB 2002754 A GB2002754 A GB 2002754A GB 7831324 A GB7831324 A GB 7831324A GB 7831324 A GB7831324 A GB 7831324A GB 2002754 A GB2002754 A GB 2002754A
Authority
GB
United Kingdom
Prior art keywords
anthracycline antibiotics
antitumor anthracycline
antitumor
antibiotics
tetrahydropyranylation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7831324A
Other versions
GB2002754B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Publication of GB2002754A publication Critical patent/GB2002754A/en
Application granted granted Critical
Publication of GB2002754B publication Critical patent/GB2002754B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

C-4' and/or C-14 tetrahydropyranyloxy derivatives of adriamycin and daunomycin prepared by the tetrahydropyranylation, which have antimicrobial and antitumor properties.
GB7831324A 1977-08-05 1978-07-27 Antitumor anthracycline antibiotics Expired GB2002754B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9434877A JPS5430146A (en) 1977-08-05 1977-08-05 Novel anthracycline derivatives and their preparation

Publications (2)

Publication Number Publication Date
GB2002754A true GB2002754A (en) 1979-02-28
GB2002754B GB2002754B (en) 1982-02-10

Family

ID=14107771

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7831324A Expired GB2002754B (en) 1977-08-05 1978-07-27 Antitumor anthracycline antibiotics

Country Status (19)

Country Link
JP (1) JPS5430146A (en)
AT (1) AT361622B (en)
AU (1) AU510946B2 (en)
BE (1) BE869395A (en)
CA (1) CA1120925A (en)
DE (1) DE2831579C3 (en)
DK (1) DK152677C (en)
ES (1) ES472306A1 (en)
FI (1) FI63420C (en)
FR (1) FR2399439A1 (en)
GB (1) GB2002754B (en)
GR (1) GR63951B (en)
HK (1) HK18683A (en)
IE (1) IE47252B1 (en)
IT (1) IT1160574B (en)
NL (1) NL174147C (en)
SE (1) SE443565B (en)
SG (1) SG5383G (en)
ZA (1) ZA784033B (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0039060A1 (en) * 1980-04-26 1981-11-04 Zaidanhojin Biseibutsu Kagaku Kenkyukai A new method for preparation of anthracycline derivatives
EP0131232A1 (en) * 1983-07-07 1985-01-16 Microbial Chemistry Research Foundation Stereoselective process for the preparation of anthracycline derivatives
EP0290744A2 (en) * 1987-03-14 1988-11-17 Kirin Beer Kabushiki Kaisha Anthracycline compounds and use thereof
US11865102B2 (en) 2018-04-27 2024-01-09 GW Research Limited Cannabidiol preparations and its uses
US11963937B2 (en) 2014-06-17 2024-04-23 GW Research Limited Use of cannabinoids in the treatment of epilepsy

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK160616C (en) * 1979-02-03 1991-09-02 Zaidan Hojin Biseibutsu PROCEDURE FOR PREPARING ANTHRACYCLINE DERIVATIVES OR ACID ADDITIONAL SALTS THEREOF
JPS6083171U (en) * 1983-11-15 1985-06-08 タキゲン製造株式会社 hinge
DE19544532C2 (en) * 1995-11-29 1997-12-11 Pharma Dynamics Gmbh Method for producing a doxorubicin lyophilisate
KR19990084528A (en) * 1998-05-07 1999-12-06 박상철 New anthracycline derivatives and preparation methods

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0039060A1 (en) * 1980-04-26 1981-11-04 Zaidanhojin Biseibutsu Kagaku Kenkyukai A new method for preparation of anthracycline derivatives
US4360664A (en) * 1980-04-26 1982-11-23 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Anthracycline glycoside 14-halo,4'-ether
EP0131232A1 (en) * 1983-07-07 1985-01-16 Microbial Chemistry Research Foundation Stereoselective process for the preparation of anthracycline derivatives
EP0290744A2 (en) * 1987-03-14 1988-11-17 Kirin Beer Kabushiki Kaisha Anthracycline compounds and use thereof
EP0290744A3 (en) * 1987-03-14 1989-12-20 Kirin Beer Kabushiki Kaisha Anthracycline compounds and use thereof
US11963937B2 (en) 2014-06-17 2024-04-23 GW Research Limited Use of cannabinoids in the treatment of epilepsy
US11865102B2 (en) 2018-04-27 2024-01-09 GW Research Limited Cannabidiol preparations and its uses

Also Published As

Publication number Publication date
IT1160574B (en) 1987-03-11
NL174147C (en) 1984-05-01
DE2831579B2 (en) 1980-01-24
AU510946B2 (en) 1980-07-24
JPS5647194B2 (en) 1981-11-07
ES472306A1 (en) 1979-10-01
NL7807906A (en) 1979-02-07
IE47252B1 (en) 1984-02-08
FR2399439A1 (en) 1979-03-02
FI782388A (en) 1979-02-06
JPS5430146A (en) 1979-03-06
FR2399439B1 (en) 1981-07-17
DK152677C (en) 1988-10-24
NL174147B (en) 1983-12-01
DK343878A (en) 1979-02-06
DE2831579C3 (en) 1980-09-18
DK152677B (en) 1988-04-11
AU3844678A (en) 1980-01-31
CA1120925A (en) 1982-03-30
ATA561278A (en) 1980-08-15
SE7808304L (en) 1979-02-06
SG5383G (en) 1983-09-09
BE869395A (en) 1978-11-16
AT361622B (en) 1981-03-25
FI63420B (en) 1983-02-28
ZA784033B (en) 1979-07-25
DE2831579A1 (en) 1979-02-15
HK18683A (en) 1983-06-10
FI63420C (en) 1983-06-10
GB2002754B (en) 1982-02-10
SE443565B (en) 1986-03-03
IT7868847A0 (en) 1978-08-03
IE781566L (en) 1979-02-05
GR63951B (en) 1980-01-16

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Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Effective date: 19980726