JPS54160394A - Preparation of 1-(5-oxo-hexyl)theobromine - Google Patents

Preparation of 1-(5-oxo-hexyl)theobromine

Info

Publication number
JPS54160394A
JPS54160394A JP6746978A JP6746978A JPS54160394A JP S54160394 A JPS54160394 A JP S54160394A JP 6746978 A JP6746978 A JP 6746978A JP 6746978 A JP6746978 A JP 6746978A JP S54160394 A JPS54160394 A JP S54160394A
Authority
JP
Japan
Prior art keywords
theobromine
formula
compound
oxo
hexyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6746978A
Other languages
Japanese (ja)
Inventor
Yukinari Kobayashi
Takanori Sone
Mikio Wakabayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Chemical Industry Co Ltd
Original Assignee
Asahi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Chemical Industry Co Ltd filed Critical Asahi Chemical Industry Co Ltd
Priority to JP6746978A priority Critical patent/JPS54160394A/en
Publication of JPS54160394A publication Critical patent/JPS54160394A/en
Pending legal-status Critical Current

Links

Abstract

PURPOSE: To obtain the title compound useful as vasodilators and hematocytolysis promotors in high yield and purity in a simple process, by reacting theobromine with easily available 6-hydroxy-2-hexanone in the presence of a specific condensing agent.
CONSTITUTION: Theobromine (T) of formula I condensed with a compound (C) of formula III through dehydration in the presence of a compound (D) of formula II at a molar ratio of (T) : (C) : (D) of 1:1.2W5:1.2W5 at 50W200°C to give 1- (5-oxohexyl)-theobromine of formula IV. The compound of formula III is readily obtained by hydrolyzing 2-methyl-3-ethoxycarbonyl-5,6-dihydropyran with a dilute acid, and by decarboxylating the hydrolysis product.
COPYRIGHT: (C)1979,JPO&Japio
JP6746978A 1978-06-05 1978-06-05 Preparation of 1-(5-oxo-hexyl)theobromine Pending JPS54160394A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP6746978A JPS54160394A (en) 1978-06-05 1978-06-05 Preparation of 1-(5-oxo-hexyl)theobromine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6746978A JPS54160394A (en) 1978-06-05 1978-06-05 Preparation of 1-(5-oxo-hexyl)theobromine

Publications (1)

Publication Number Publication Date
JPS54160394A true JPS54160394A (en) 1979-12-19

Family

ID=13345839

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6746978A Pending JPS54160394A (en) 1978-06-05 1978-06-05 Preparation of 1-(5-oxo-hexyl)theobromine

Country Status (1)

Country Link
JP (1) JPS54160394A (en)

Similar Documents

Publication Publication Date Title
JPS54160394A (en) Preparation of 1-(5-oxo-hexyl)theobromine
JPS5430156A (en) Synthesis of benzamide derivative
JPS54144320A (en) Preparation of ureidomethylene malonic ester
JPS5665838A (en) Preparation of beta-alkoxymethoxymethyl halide
SU1477729A1 (en) Method of producing 4-hydroxy-8-carboxyquinolone-2
JPS54148740A (en) Production of 3-methyl-2-cyclopentene-1-one
JPS5711981A (en) Theobromine derivative and its preparation
JPS5432480A (en) Novel preparation of piperidine derivatives
JPS57106678A (en) Preparation of dibenzothiepinpropionic acid derivative
SU1035034A1 (en) Process for preparing carbamide resin
JPS5640638A (en) Preparation of pyruvic acid
JPS55141471A (en) Preparation of alpha-dimethylamino-epsilon-caprolactam
JPS5527129A (en) Preparation of tryptophan derivative
JPS5782345A (en) Preparation of lactic ester
JPS57203091A (en) Production of organogermanium compound
JPS5536431A (en) Preparation of farnesylacetic acid
JPS5517360A (en) Preparation of aromatic nitrile
JPS5770865A (en) Preparation of 5-aroylpyrrole-2-acetic acid derivative
JPS55108856A (en) Preparation of 1-alkyl-3-methyl-5-pyrazolone
JPS57179175A (en) Preparation of 2-benzothiazolinone derivative or salt thereof
JPS5337674A (en) Preparation of pyrazinecarbamoylcarboxylic acid
JPS54112842A (en) Preparation of alpha-biphenylyl-propionic acid derivative
JPS55111440A (en) Preparation of straight-chain higher carboxylic acid
JPS5520706A (en) Preparation of metoclopramide
JPS6470431A (en) 1-(6-methoxy-2-naphthyl)-2-oxy-1-alkanone acetal