JPS54130559A - Preapration of derivative of oxygen-containing heterocyclic compound - Google Patents
Preapration of derivative of oxygen-containing heterocyclic compoundInfo
- Publication number
- JPS54130559A JPS54130559A JP3762878A JP3762878A JPS54130559A JP S54130559 A JPS54130559 A JP S54130559A JP 3762878 A JP3762878 A JP 3762878A JP 3762878 A JP3762878 A JP 3762878A JP S54130559 A JPS54130559 A JP S54130559A
- Authority
- JP
- Japan
- Prior art keywords
- derivative
- preapration
- oxygen
- aryl
- heterocyclic compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Furan Compounds (AREA)
- Pyrane Compounds (AREA)
Abstract
PURPOSE: To prepare a tetrahydrofuran derivative, etc. useful as an intermediate of pharmaceuticals, etc., in high purity and yield, by the reaction of 2-alkoxytetrahydrofuran derivative, etc. with an enol derivative in an inert solvent in the presence of a Lewis acid catalyst.
CONSTITUTION: The tetrahydrofuran (or pyran) derivative III is prepared by reacting a 2-alkoxytetrahydrofuran (or pyran) derivative I (n is 1, 2: R is H, alkyl, aryl, aralkyl; R' is lower alkyl) with an enol derivative II [R1-3 are H, alkyl, aryl, aralkyl; or two of them may together form a ring; X is -Si(R")3, -CO-R'" (R" is lower alkyl; R'" is lower alkyl, aryl, etc.), in an inert solvent such as halogenated hydrocarbon, in the presence of a Lewis acid such as TiCl4, at -100 - +25°C.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3762878A JPS6049195B2 (en) | 1978-03-31 | 1978-03-31 | Method for producing oxygen-containing heterocyclic compound derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3762878A JPS6049195B2 (en) | 1978-03-31 | 1978-03-31 | Method for producing oxygen-containing heterocyclic compound derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS54130559A true JPS54130559A (en) | 1979-10-09 |
JPS6049195B2 JPS6049195B2 (en) | 1985-10-31 |
Family
ID=12502894
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP3762878A Expired JPS6049195B2 (en) | 1978-03-31 | 1978-03-31 | Method for producing oxygen-containing heterocyclic compound derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6049195B2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63194766A (en) * | 1987-02-05 | 1988-08-11 | Inoue Kinzoku Kogyo Kk | Coater |
-
1978
- 1978-03-31 JP JP3762878A patent/JPS6049195B2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
JPS6049195B2 (en) | 1985-10-31 |
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