JPS6440468A - Novel indenoimidazole derivative - Google Patents

Novel indenoimidazole derivative

Info

Publication number
JPS6440468A
JPS6440468A JP19611687A JP19611687A JPS6440468A JP S6440468 A JPS6440468 A JP S6440468A JP 19611687 A JP19611687 A JP 19611687A JP 19611687 A JP19611687 A JP 19611687A JP S6440468 A JPS6440468 A JP S6440468A
Authority
JP
Japan
Prior art keywords
compound
formula
reacting
drug
prevention
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP19611687A
Other languages
Japanese (ja)
Other versions
JPH078861B2 (en
Inventor
Masayoshi Tsuji
Toshitaka Inoue
Koichi Ikesue
Noriyuki Fujimoto
Kanji Noda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hisamitsu Pharmaceutical Co Inc
Original Assignee
Hisamitsu Pharmaceutical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co Inc filed Critical Hisamitsu Pharmaceutical Co Inc
Priority to JP19611687A priority Critical patent/JPH078861B2/en
Publication of JPS6440468A publication Critical patent/JPS6440468A/en
Publication of JPH078861B2 publication Critical patent/JPH078861B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Landscapes

  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:The compound of formula I [X and Y are H, halogen, lower alkyl or lower alkoxy; m is 0 or 1; n is 1-3; R is (substituted)phenyl, (substituted)pyridyl or morpholino] and its acid addition salt useful as a drug. EXAMPLE:2-(2-Pyridylmethyl)thio-8H-indeno[1,2-d]imidazole. USE:A drug. It has excellent antitumor action, low side effect and high safety and is useful as an antiulcer agent for the remedy, prevention and relapse- prevention of ulcer. PREPARATION:The compound of formula I wherein m is 0 can be produced by reacting a compound of formula II with a compound of formula III in an organic solvent (e.g. methanol) at 20-120 deg.C for 1-48hr. The product can be converted to another compound of formula I wherein m is 1 by reacting with an oxidizing agent (e.g. m-chloroperbenzoic acid) in an organic solvent (e.g. dichloromethane) at -15-+30 deg.C for 5min-24hr.
JP19611687A 1987-08-04 1987-08-04 Novel indenoimidazole derivative Expired - Lifetime JPH078861B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP19611687A JPH078861B2 (en) 1987-08-04 1987-08-04 Novel indenoimidazole derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP19611687A JPH078861B2 (en) 1987-08-04 1987-08-04 Novel indenoimidazole derivative

Publications (2)

Publication Number Publication Date
JPS6440468A true JPS6440468A (en) 1989-02-10
JPH078861B2 JPH078861B2 (en) 1995-02-01

Family

ID=16352507

Family Applications (1)

Application Number Title Priority Date Filing Date
JP19611687A Expired - Lifetime JPH078861B2 (en) 1987-08-04 1987-08-04 Novel indenoimidazole derivative

Country Status (1)

Country Link
JP (1) JPH078861B2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998013356A1 (en) * 1996-09-25 1998-04-02 Takeda Chemical Industries, Ltd. Trycyclic compounds as prostaglandin i2 receptor agonists
JP2007181534A (en) * 2006-01-05 2007-07-19 Kb Seiren Ltd Portable shoe cleaner

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998013356A1 (en) * 1996-09-25 1998-04-02 Takeda Chemical Industries, Ltd. Trycyclic compounds as prostaglandin i2 receptor agonists
US6248766B1 (en) 1996-09-25 2001-06-19 Takeda Chemical Industries, Ltd. Tricyclic compounds, their production and use
US6417213B2 (en) 1996-09-25 2002-07-09 Takeda Chemical Industries, Ltd. Tricyclic compound, their production and use
JP2007181534A (en) * 2006-01-05 2007-07-19 Kb Seiren Ltd Portable shoe cleaner

Also Published As

Publication number Publication date
JPH078861B2 (en) 1995-02-01

Similar Documents

Publication Publication Date Title
DK444685A (en) TIAZOLIDE INDION DERIVATIVES, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND PROCEDURES FOR PREPARING THEREOF
HU913062D0 (en) Method for producing benzol, pyridyl and pyridine derivatives and pharmaceutical preparatives containing such compounds
KR890000467A (en) Pyridine derivatives and ulcers containing them
JPS6440467A (en) Novel substituted diphenylimidazole derivative
GB1500255A (en) Process for the preparation of 2,4-dioxo-1,2,3,4-tetrahydro-s-triazine-(1,2-a)-benzimidazoles
JPS6440468A (en) Novel indenoimidazole derivative
JPS5649364A (en) Carbostyril derivative
EP0331080A3 (en) Imidazole derivatives, process for production thereof, and use thereof
EP0031388A4 (en) Process for preparing imidazole derivatives.
JPS6479177A (en) Pyridine derivative and remedy containing said derivative for ulcer
JPS5553247A (en) Novel benzylamine derivative
JPS56164184A (en) Novel piperidine derivative
JPS57106663A (en) 1,4-disubstituted piperazine derivative and its preparation
JPS5527142A (en) Novel 1-phthalazone derivative
JPS5551069A (en) Preparation of benzimidazole derivative
JPS6466181A (en) Quinolypyrimidine derivative, its production and plant blight controlling agent containing said derivative as active component
JPS55151547A (en) Production of guanidinocapronic ester
JPS57144277A (en) Cyclopentabenzofuran derivative
JPS54130559A (en) Preapration of derivative of oxygen-containing heterocyclic compound
JPS54132571A (en) 4-imino-imidazolidine-2,5-dithione derivative
JPS54112867A (en) 1,3-dithiethane compound and its preparation
JPS5764662A (en) Alkylene disulfur derivative
JPS5735568A (en) Preparation of cyclohexanol-2,2,6,6,-tetrakis hydroxymethyl tetranicotinate
JPS57102888A (en) Carbostyril derivative
JPS5470278A (en) Indolinethione derivatives