JPS6440468A - Novel indenoimidazole derivative - Google Patents
Novel indenoimidazole derivativeInfo
- Publication number
- JPS6440468A JPS6440468A JP19611687A JP19611687A JPS6440468A JP S6440468 A JPS6440468 A JP S6440468A JP 19611687 A JP19611687 A JP 19611687A JP 19611687 A JP19611687 A JP 19611687A JP S6440468 A JPS6440468 A JP S6440468A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- reacting
- drug
- prevention
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:The compound of formula I [X and Y are H, halogen, lower alkyl or lower alkoxy; m is 0 or 1; n is 1-3; R is (substituted)phenyl, (substituted)pyridyl or morpholino] and its acid addition salt useful as a drug. EXAMPLE:2-(2-Pyridylmethyl)thio-8H-indeno[1,2-d]imidazole. USE:A drug. It has excellent antitumor action, low side effect and high safety and is useful as an antiulcer agent for the remedy, prevention and relapse- prevention of ulcer. PREPARATION:The compound of formula I wherein m is 0 can be produced by reacting a compound of formula II with a compound of formula III in an organic solvent (e.g. methanol) at 20-120 deg.C for 1-48hr. The product can be converted to another compound of formula I wherein m is 1 by reacting with an oxidizing agent (e.g. m-chloroperbenzoic acid) in an organic solvent (e.g. dichloromethane) at -15-+30 deg.C for 5min-24hr.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP19611687A JPH078861B2 (en) | 1987-08-04 | 1987-08-04 | Novel indenoimidazole derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP19611687A JPH078861B2 (en) | 1987-08-04 | 1987-08-04 | Novel indenoimidazole derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS6440468A true JPS6440468A (en) | 1989-02-10 |
JPH078861B2 JPH078861B2 (en) | 1995-02-01 |
Family
ID=16352507
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP19611687A Expired - Lifetime JPH078861B2 (en) | 1987-08-04 | 1987-08-04 | Novel indenoimidazole derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPH078861B2 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998013356A1 (en) * | 1996-09-25 | 1998-04-02 | Takeda Chemical Industries, Ltd. | Trycyclic compounds as prostaglandin i2 receptor agonists |
JP2007181534A (en) * | 2006-01-05 | 2007-07-19 | Kb Seiren Ltd | Portable shoe cleaner |
-
1987
- 1987-08-04 JP JP19611687A patent/JPH078861B2/en not_active Expired - Lifetime
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998013356A1 (en) * | 1996-09-25 | 1998-04-02 | Takeda Chemical Industries, Ltd. | Trycyclic compounds as prostaglandin i2 receptor agonists |
US6248766B1 (en) | 1996-09-25 | 2001-06-19 | Takeda Chemical Industries, Ltd. | Tricyclic compounds, their production and use |
US6417213B2 (en) | 1996-09-25 | 2002-07-09 | Takeda Chemical Industries, Ltd. | Tricyclic compound, their production and use |
JP2007181534A (en) * | 2006-01-05 | 2007-07-19 | Kb Seiren Ltd | Portable shoe cleaner |
Also Published As
Publication number | Publication date |
---|---|
JPH078861B2 (en) | 1995-02-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK444685A (en) | TIAZOLIDE INDION DERIVATIVES, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND PROCEDURES FOR PREPARING THEREOF | |
HU913062D0 (en) | Method for producing benzol, pyridyl and pyridine derivatives and pharmaceutical preparatives containing such compounds | |
KR890000467A (en) | Pyridine derivatives and ulcers containing them | |
JPS6440467A (en) | Novel substituted diphenylimidazole derivative | |
GB1500255A (en) | Process for the preparation of 2,4-dioxo-1,2,3,4-tetrahydro-s-triazine-(1,2-a)-benzimidazoles | |
JPS6440468A (en) | Novel indenoimidazole derivative | |
JPS5649364A (en) | Carbostyril derivative | |
EP0331080A3 (en) | Imidazole derivatives, process for production thereof, and use thereof | |
EP0031388A4 (en) | Process for preparing imidazole derivatives. | |
JPS6479177A (en) | Pyridine derivative and remedy containing said derivative for ulcer | |
JPS5553247A (en) | Novel benzylamine derivative | |
JPS56164184A (en) | Novel piperidine derivative | |
JPS57106663A (en) | 1,4-disubstituted piperazine derivative and its preparation | |
JPS5527142A (en) | Novel 1-phthalazone derivative | |
JPS5551069A (en) | Preparation of benzimidazole derivative | |
JPS6466181A (en) | Quinolypyrimidine derivative, its production and plant blight controlling agent containing said derivative as active component | |
JPS55151547A (en) | Production of guanidinocapronic ester | |
JPS57144277A (en) | Cyclopentabenzofuran derivative | |
JPS54130559A (en) | Preapration of derivative of oxygen-containing heterocyclic compound | |
JPS54132571A (en) | 4-imino-imidazolidine-2,5-dithione derivative | |
JPS54112867A (en) | 1,3-dithiethane compound and its preparation | |
JPS5764662A (en) | Alkylene disulfur derivative | |
JPS5735568A (en) | Preparation of cyclohexanol-2,2,6,6,-tetrakis hydroxymethyl tetranicotinate | |
JPS57102888A (en) | Carbostyril derivative | |
JPS5470278A (en) | Indolinethione derivatives |