JPS54117441A - Preparation of 2-hydroxy-2-cycloalken-1-ones and their intermediates - Google Patents
Preparation of 2-hydroxy-2-cycloalken-1-ones and their intermediatesInfo
- Publication number
- JPS54117441A JPS54117441A JP2284078A JP2284078A JPS54117441A JP S54117441 A JPS54117441 A JP S54117441A JP 2284078 A JP2284078 A JP 2284078A JP 2284078 A JP2284078 A JP 2284078A JP S54117441 A JPS54117441 A JP S54117441A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- alkyl
- oxidizing
- solvent
- acetate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: To prepare the title compound useful as a durable modifier of perfumes for foods, cosmetics, etc., easily, economically in high yield and short reaction process, by oxidizing 3-alkyl-substituted or unsubstituted 1,2-bis-trialkylsilyloxy cycloalkene with an oxidizing agent.
CONSTITUTION: The compound (1) is prepared by oxidizing the compound (2) with an oxidizing agent (e.g. Cu acetate, Hg acetate, etc.) in a solvent such as methanol, pref. at 10W50°C. The compound (2) can be prepared by reacting a dibasic acid dihalide (3) (R1 is H, 1-6C alkyl; X is Cl, Br, I; n is 2-7) (e.g. glutaroyl chloride) with a trialkylsilylhalide (4) (R is 1-5C alkyl), in an inert solvent such as hexane, in the presence of an alkali metal (Li, Na, etc.) or its Hg amalgam, at a temperature near the boiling point of the solvent.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2284078A JPS54117441A (en) | 1978-03-02 | 1978-03-02 | Preparation of 2-hydroxy-2-cycloalken-1-ones and their intermediates |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2284078A JPS54117441A (en) | 1978-03-02 | 1978-03-02 | Preparation of 2-hydroxy-2-cycloalken-1-ones and their intermediates |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS54117441A true JPS54117441A (en) | 1979-09-12 |
JPS6123778B2 JPS6123778B2 (en) | 1986-06-07 |
Family
ID=12093894
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2284078A Granted JPS54117441A (en) | 1978-03-02 | 1978-03-02 | Preparation of 2-hydroxy-2-cycloalken-1-ones and their intermediates |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS54117441A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104592284A (en) * | 2013-10-30 | 2015-05-06 | 新亚强硅化学江苏有限公司 | 1,2-bis(trimethylsilyloxy)cyclohexene, and preparation method thereof |
CN104592285A (en) * | 2013-10-30 | 2015-05-06 | 新亚强硅化学江苏有限公司 | 1,2-bis(trimethylsilyloxy)cyclopentene, and preparation method thereof |
CN104592287A (en) * | 2013-10-30 | 2015-05-06 | 新亚强硅化学江苏有限公司 | 1,2-bis(trimethylsilyloxy)cyclobutene, and preparation method thereof |
KR20180079315A (en) * | 2015-11-03 | 2018-07-10 | 체하테 에르. 바이트리히 게엠베하 | Continuous reaction method using fine particle alkali metal dispersion |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1352460A (en) * | 1972-06-02 | 1974-05-08 | Pfizer | 2-hydroxy-3,5-diethylenecyclopeht-2-en-1-one and its use as a flavouring agent |
-
1978
- 1978-03-02 JP JP2284078A patent/JPS54117441A/en active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1352460A (en) * | 1972-06-02 | 1974-05-08 | Pfizer | 2-hydroxy-3,5-diethylenecyclopeht-2-en-1-one and its use as a flavouring agent |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104592284A (en) * | 2013-10-30 | 2015-05-06 | 新亚强硅化学江苏有限公司 | 1,2-bis(trimethylsilyloxy)cyclohexene, and preparation method thereof |
CN104592285A (en) * | 2013-10-30 | 2015-05-06 | 新亚强硅化学江苏有限公司 | 1,2-bis(trimethylsilyloxy)cyclopentene, and preparation method thereof |
CN104592287A (en) * | 2013-10-30 | 2015-05-06 | 新亚强硅化学江苏有限公司 | 1,2-bis(trimethylsilyloxy)cyclobutene, and preparation method thereof |
KR20180079315A (en) * | 2015-11-03 | 2018-07-10 | 체하테 에르. 바이트리히 게엠베하 | Continuous reaction method using fine particle alkali metal dispersion |
JP2018536029A (en) * | 2015-11-03 | 2018-12-06 | ツェーハーテー エグ. バイトリッヒ ゲーエムベーハー | A continuous process for reaction with particulate alkali metal dispersions. |
Also Published As
Publication number | Publication date |
---|---|
JPS6123778B2 (en) | 1986-06-07 |
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