JPS54117442A - Preparation of macrocyclic ketone, its novel intermediate and its preparation - Google Patents

Preparation of macrocyclic ketone, its novel intermediate and its preparation

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Publication number
JPS54117442A
JPS54117442A JP2354578A JP2354578A JPS54117442A JP S54117442 A JPS54117442 A JP S54117442A JP 2354578 A JP2354578 A JP 2354578A JP 2354578 A JP2354578 A JP 2354578A JP S54117442 A JPS54117442 A JP S54117442A
Authority
JP
Japan
Prior art keywords
preparation
compound
pref
prepared
reducing agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2354578A
Other languages
Japanese (ja)
Other versions
JPS6225649B2 (en
Inventor
Masanao Matsui
Takeshi Kitahara
Yasuhiro Katsuta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
T Hasegawa Co Ltd
Original Assignee
T Hasegawa Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by T Hasegawa Co Ltd filed Critical T Hasegawa Co Ltd
Priority to JP2354578A priority Critical patent/JPS54117442A/en
Publication of JPS54117442A publication Critical patent/JPS54117442A/en
Publication of JPS6225649B2 publication Critical patent/JPS6225649B2/ja
Granted legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: To prepare the title compound useful as a modifier of perfumes having mask-or civet-note, easily, economically, in high yield and short process, by reducing a macrocyclic 1,2-bis-trialkylsilyloxy-cycloalkene with a reducing agent.
CONSTITUTION: The objective compound (1) is prepared by adding a reducing agent (e.g. Zn, Sn, etc.) dropwise to the compound (2) pref. under acidic condition, at 0W200°C, pref. 0W70°C. The compound (2) can be prepared by reacting an α, ω-dibasic acid dihalide (3) (X is Cl, Br, I; n is 8W15), e.g. 1,9-nonane dicarboxylic acid chloride, with trialkylsilyl halide (4) (R is 1W5C alkyl), in an inert organic solvent such as hexane, under anhydrous conditions, in the presence of an alkali metal (Li, Na, etc.) or its Hg amalgam, at a temperature near the boiling point of the solvent.
COPYRIGHT: (C)1979,JPO&Japio
JP2354578A 1978-03-03 1978-03-03 Preparation of macrocyclic ketone, its novel intermediate and its preparation Granted JPS54117442A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2354578A JPS54117442A (en) 1978-03-03 1978-03-03 Preparation of macrocyclic ketone, its novel intermediate and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2354578A JPS54117442A (en) 1978-03-03 1978-03-03 Preparation of macrocyclic ketone, its novel intermediate and its preparation

Publications (2)

Publication Number Publication Date
JPS54117442A true JPS54117442A (en) 1979-09-12
JPS6225649B2 JPS6225649B2 (en) 1987-06-04

Family

ID=12113435

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2354578A Granted JPS54117442A (en) 1978-03-03 1978-03-03 Preparation of macrocyclic ketone, its novel intermediate and its preparation

Country Status (1)

Country Link
JP (1) JPS54117442A (en)

Also Published As

Publication number Publication date
JPS6225649B2 (en) 1987-06-04

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