JPS5384957A - Branched and alicyclic esters of androstane and estrane system and pharmaceutical composition containing same - Google Patents

Branched and alicyclic esters of androstane and estrane system and pharmaceutical composition containing same

Info

Publication number
JPS5384957A
JPS5384957A JP14106677A JP14106677A JPS5384957A JP S5384957 A JPS5384957 A JP S5384957A JP 14106677 A JP14106677 A JP 14106677A JP 14106677 A JP14106677 A JP 14106677A JP S5384957 A JPS5384957 A JP S5384957A
Authority
JP
Japan
Prior art keywords
estrane
androstane
branched
pharmaceutical composition
composition containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP14106677A
Other languages
English (en)
Inventor
Yosefu Uiruherumu Ma Ranberuto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo NV
Original Assignee
Akzo NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo NV filed Critical Akzo NV
Publication of JPS5384957A publication Critical patent/JPS5384957A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C07J1/0074—Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C07J1/0025—Esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP14106677A 1976-11-26 1977-11-24 Branched and alicyclic esters of androstane and estrane system and pharmaceutical composition containing same Pending JPS5384957A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7613248A NL7613248A (nl) 1976-11-26 1976-11-26 Werkwijze voor het bereiden van nieuwe steroid- esters.

Publications (1)

Publication Number Publication Date
JPS5384957A true JPS5384957A (en) 1978-07-26

Family

ID=19827290

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14106677A Pending JPS5384957A (en) 1976-11-26 1977-11-24 Branched and alicyclic esters of androstane and estrane system and pharmaceutical composition containing same

Country Status (13)

Country Link
US (5) US4212864A (ja)
JP (1) JPS5384957A (ja)
BE (1) BE861224A (ja)
CA (1) CA1095895A (ja)
CH (1) CH637143A5 (ja)
DE (1) DE2752695A1 (ja)
DK (1) DK146221C (ja)
ES (1) ES464504A1 (ja)
FR (1) FR2373560A1 (ja)
GB (1) GB1593515A (ja)
IE (1) IE46092B1 (ja)
NL (1) NL7613248A (ja)
SE (1) SE7713341L (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0816117B2 (ja) * 1985-06-25 1996-02-21 エス・ア−ル・アイ・インタ−ナシヨナル ９α，１１β−置換および１１β−置換エストラン

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7613248A (nl) * 1976-11-26 1978-05-30 Akzo Nv Werkwijze voor het bereiden van nieuwe steroid- esters.
US4851402A (en) * 1987-02-27 1989-07-25 International Minerals & Chemical Corp. Estriol growth promotant
US5137882A (en) * 1990-06-11 1992-08-11 Holt Dennis A Steroidal 3-acetic acid derivatives as 5-alpha-reductase inhibitors
US5238929A (en) * 1991-10-22 1993-08-24 Development Products, Inc. Correction of tribology of arthritis-affected joints and medicine for its implementation
US5504074A (en) * 1993-08-06 1996-04-02 Children's Medical Center Corporation Estrogenic compounds as anti-angiogenic agents
US20040214807A1 (en) * 1993-08-06 2004-10-28 D'amato Robert J. Estrogenic compounds as anti-mitotic agents
US6908910B2 (en) * 1993-08-06 2005-06-21 The Children's Medical Center Corporation Estrogenic compounds as anti-mitotic agents
US6346510B1 (en) 1995-10-23 2002-02-12 The Children's Medical Center Corporation Therapeutic antiangiogenic endostatin compositions
US20020002294A1 (en) * 1997-09-24 2002-01-03 D' Amato Robert J. Estrogenic compounds as antiangiogenic agents
EP1124545B1 (en) 1998-08-11 2004-12-15 EntreMed, Inc. Use of 2-methoxyestradiol as anti-fungal agents
US20030083231A1 (en) * 1998-11-24 2003-05-01 Ahlem Clarence N. Blood cell deficiency treatment method
DE19906159A1 (de) * 1999-02-09 2000-08-10 Schering Ag 16-Hydroxyestratriene als selektiv wirksame Estrogene
ES2246234T3 (es) 1999-05-04 2006-02-16 Strakan International Limited Glicosidos de androgenos y actividad androgenica de los mismos.
US7087592B1 (en) * 1999-08-23 2006-08-08 Entre Med, Inc. Compositions comprising purified 2-methoxyestradiol and methods of producing same
US7135581B2 (en) 2000-08-18 2006-11-14 Entremed, Inc. Antiangiogenic agents
US6995278B2 (en) 2000-08-18 2006-02-07 Entre Med, Inc. Antiangiogenic agents
US20050192258A1 (en) * 2000-08-18 2005-09-01 Agoston Gregory E. Antiangiogenic agents
WO2002022645A2 (en) * 2000-09-14 2002-03-21 Accelerated Pharmaceuticals, Inc. Method of making 7alpha-methyl-11beta-methoxy estradiol and related compounds with estrogenic activity
AU2003209439A1 (en) * 2002-01-30 2003-09-02 Entremed, Inc. Non-steroidal analogs of 2-methoxyestradiol
EP1633367A2 (en) * 2003-05-28 2006-03-15 EntreMed, Inc. Antiangiogenic agents
CA2558014A1 (en) 2004-03-12 2005-09-29 Entremed, Inc. Antiangiogenic agents
US20070004689A1 (en) * 2004-03-12 2007-01-04 Agoston Gregory E Antiangiogenic agents
CA2587448A1 (en) * 2004-11-29 2006-06-01 Entremed, Inc. A method of administering anti-angiogenic agents and a method of treating disease using same
US20070185069A1 (en) * 2005-11-14 2007-08-09 Plum Stacy M Anti-angiogenic activity of 2-methoxyestradiol in combination with anti-cancer agents
US20070176403A1 (en) * 2006-02-01 2007-08-02 Dennis Calderone Air adjustable seat
CA2646065C (en) * 2006-03-20 2014-01-14 Entremed, Inc. Disease modifying anti-arthritic activity of 2-methoxyestradiol
US20080234243A1 (en) * 2007-01-31 2008-09-25 Lavallee Theresa M Method of treating amyloidosis mediated diseases
AU2013386732B2 (en) * 2013-04-18 2018-10-18 Xi'an Libang Pharmaceutical Technology Co., Ltd. Ester derivative of 7-alpha-[9-(4,4,5,5,5-pentafluoropentylsulphinyl)nonyl]oestra-1,3,5(10)-triene-3,17beta-diol having antitumour activity and preparation method thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB826790A (en) * 1957-05-07 1960-01-20 British Drug Houses Ltd Improvements in or relating to the preparation of cyclopentanophenanthrene compounds
DE1117113B (de) * 1959-12-05 1961-11-16 Schering Ag Verfahren zur Herstellung ª‡ú¼ ª‰-ungesaettigter Ketosteroide, die am ª‰-staendigen Kohlenstoffatom eine Methylgruppe tragen
US3018297A (en) * 1960-02-29 1962-01-23 Searle & Co 1, 3- and 1, 4-bisoxygenated estra-1, 3, 5(10)-trienes and intermediates
CH399447A (de) * 1961-04-14 1965-09-30 Ciba Geigy Verfahren zur Herstellung eines neuen Steroid-Hormon-Esters
US3226991A (en) * 1962-12-17 1966-01-04 United Carr Fastener Corp Indexing device for a rotary snap switch
FR5519M (ja) * 1966-06-07 1967-11-06
NL189235C (nl) * 1974-02-28 1993-02-16 Akzo Nv Werkwijze voor de bereiding van een oraal toe te dienen farmaceutisch preparaat met androgene werking.
US4098802A (en) * 1975-02-18 1978-07-04 Akzona Incorporated Oral pharmaceutical preparation having androgenic activity
US4147783A (en) * 1974-02-28 1979-04-03 Akzona Incorporated Oral pharmaceutical preparation
NL7506407A (nl) * 1975-05-30 1976-12-02 Akzo Nv Werkwijze ter bereiding van een oraal werkzaam far- maceutisch preparaat.
DE2558076C2 (de) * 1975-12-19 1983-12-15 Schering AG, 1000 Berlin und 4709 Bergkamen Depot-Steroidester, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
NL7613248A (nl) * 1976-11-26 1978-05-30 Akzo Nv Werkwijze voor het bereiden van nieuwe steroid- esters.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0816117B2 (ja) * 1985-06-25 1996-02-21 エス・ア−ル・アイ・インタ−ナシヨナル ９α，１１β−置換および１１β−置換エストラン

Also Published As

Publication number Publication date
US4329296A (en) 1982-05-11
DK146221B (da) 1983-08-01
IE46092B1 (en) 1983-02-23
DK146221C (da) 1984-01-09
GB1593515A (en) 1981-07-15
DK522277A (da) 1978-05-27
FR2373560A1 (fr) 1978-07-07
US4212864A (en) 1980-07-15
US4307086A (en) 1981-12-22
SE7713341L (sv) 1978-05-27
DE2752695A1 (de) 1978-06-01
US4307087A (en) 1981-12-22
NL7613248A (nl) 1978-05-30
IE46092L (en) 1978-05-26
CA1095895A (en) 1981-02-17
ES464504A1 (es) 1978-09-01
BE861224A (fr) 1978-05-25
CH637143A5 (de) 1983-07-15
US4312864A (en) 1982-01-26
FR2373560B1 (ja) 1980-08-22

Similar Documents

Publication Publication Date Title
JPS5384957A (en) Branched and alicyclic esters of androstane and estrane system and pharmaceutical composition containing same
GB2066072B (en) Pharmaceutical compositions containing corticosteroids and arginine esters
IL49640A0 (en) Estradiol esters and oral estrogenic preparations containing them
IL51660A (en) Hentriakontapetides being -endorphins their preparation and pharmaceutical compostions containing them
GB1557197A (en) 3-oximes of d-norgestrel esters and method for the preparation thereof
JPS5262263A (en) Esteranic steroid and pharmaceutical composition thereof
IL34713A0 (en) Anaesthetic pharmaceutical preparations containing steroids of the pregnane series and some new pregnane derivatives
AU502298B2 (en) Terpenoid esters of steroids
AU523752B2 (en) Concentrated liquid formulation of steroid and tocol
PH13537A (en) 16-methyl-9-halo steroid esters and preparation thereof
JPS51118756A (en) Novel steroids * pharmaceutical composition containing same and preparation thereof
NZ185341A (en) 19-oxygenated steroids and pharmaceutical compositions
GR62084B (en) Deposit of steroids esters
PH14606A (en) Compounds of the pregnane series with an oxygeb function in the 19-position and pharmaceutical composition containing same
NZ185296A (en) Corticoids and pharmaceutical compositions
IL53012A0 (en) Polyhalogenated steroids of the pregnane series their manufacture and pharmaceutical compositions containing them
DE3069990D1 (en) Steroid esters of methylated prostaglandin derivatives and their pharmaceutical compositions
NZ184256A (en) Oral pharmaceutical compostions comprising certain esters of methicillin
JPS5419993A (en) Penicillin esters and their preparations and medical compositions containing same
GB1532734A (en) 17-spirosultine derivatives and the corresponding ypsilon-hydroxy-acid derivatives of androst-4-en-3-one processes for preparing them and pharmaceutical compositions containing them
JPS54115361A (en) Testosterone ester*its manufacture and androgen active drug containing it
NZ189460A (en) 11-hydroxy-17-substituted pregnane derivatives and pharmaceutical compositions
JPS5248656A (en) 22fluoroo66betaafluoro steroid derivative* preparation of the same and antiphlogistic containing the sa1me
IL52952A0 (en) New hydroxymethyl-pyridine esters their preparation and pharmaceutical compositions containing them
JPS5416483A (en) Novel nnpyrimidinyl imidoacid ester *its preparation and medicine containing same