DK522277A - Forgrenede og cykloalifatiske estere af androstan og oestranraekken og farmaceutiske midler indeholdende disse - Google Patents

Forgrenede og cykloalifatiske estere af androstan og oestranraekken og farmaceutiske midler indeholdende disse

Info

Publication number
DK522277A
DK522277A DK522277A DK522277A DK522277A DK 522277 A DK522277 A DK 522277A DK 522277 A DK522277 A DK 522277A DK 522277 A DK522277 A DK 522277A DK 522277 A DK522277 A DK 522277A
Authority
DK
Denmark
Prior art keywords
austranian
cycloalifatic
androstan
esters
branched
Prior art date
Application number
DK522277A
Other languages
English (en)
Other versions
DK146221B (da
DK146221C (da
Inventor
L J W M Tax
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of DK522277A publication Critical patent/DK522277A/da
Publication of DK146221B publication Critical patent/DK146221B/da
Application granted granted Critical
Publication of DK146221C publication Critical patent/DK146221C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C07J1/0074—Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C07J1/0025—Esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK522277A 1976-11-26 1977-11-24 Analogifremgangsmaade til fremstilling af forgrenede alifatiske eller cykloalifatiske estere af 17-hydroxysteroider DK146221C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL7613248A NL7613248A (nl) 1976-11-26 1976-11-26 Werkwijze voor het bereiden van nieuwe steroid- esters.
NL7613248 1976-11-26

Publications (3)

Publication Number Publication Date
DK522277A true DK522277A (da) 1978-05-27
DK146221B DK146221B (da) 1983-08-01
DK146221C DK146221C (da) 1984-01-09

Family

ID=19827290

Family Applications (1)

Application Number Title Priority Date Filing Date
DK522277A DK146221C (da) 1976-11-26 1977-11-24 Analogifremgangsmaade til fremstilling af forgrenede alifatiske eller cykloalifatiske estere af 17-hydroxysteroider

Country Status (13)

Country Link
US (5) US4212864A (da)
JP (1) JPS5384957A (da)
BE (1) BE861224A (da)
CA (1) CA1095895A (da)
CH (1) CH637143A5 (da)
DE (1) DE2752695A1 (da)
DK (1) DK146221C (da)
ES (1) ES464504A1 (da)
FR (1) FR2373560A1 (da)
GB (1) GB1593515A (da)
IE (1) IE46092B1 (da)
NL (1) NL7613248A (da)
SE (1) SE7713341L (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7613248A (nl) * 1976-11-26 1978-05-30 Akzo Nv Werkwijze voor het bereiden van nieuwe steroid- esters.
US4705783A (en) * 1985-06-25 1987-11-10 Sri International 9α, 11β-substituted and 11β-substituted estranes
US4851402A (en) * 1987-02-27 1989-07-25 International Minerals & Chemical Corp. Estriol growth promotant
US5137882A (en) * 1990-06-11 1992-08-11 Holt Dennis A Steroidal 3-acetic acid derivatives as 5-alpha-reductase inhibitors
US5238929A (en) * 1991-10-22 1993-08-24 Development Products, Inc. Correction of tribology of arthritis-affected joints and medicine for its implementation
US20040214807A1 (en) * 1993-08-06 2004-10-28 D'amato Robert J. Estrogenic compounds as anti-mitotic agents
US6908910B2 (en) 1993-08-06 2005-06-21 The Children's Medical Center Corporation Estrogenic compounds as anti-mitotic agents
US5504074A (en) * 1993-08-06 1996-04-02 Children's Medical Center Corporation Estrogenic compounds as anti-angiogenic agents
US6346510B1 (en) 1995-10-23 2002-02-12 The Children's Medical Center Corporation Therapeutic antiangiogenic endostatin compositions
US20020002294A1 (en) * 1997-09-24 2002-01-03 D' Amato Robert J. Estrogenic compounds as antiangiogenic agents
DE69922684T2 (de) 1998-08-11 2005-10-06 Entremed, Inc. Verwendung von 2-methoxyestradiol als fungizide
US20030083231A1 (en) * 1998-11-24 2003-05-01 Ahlem Clarence N. Blood cell deficiency treatment method
DE19906159A1 (de) * 1999-02-09 2000-08-10 Schering Ag 16-Hydroxyestratriene als selektiv wirksame Estrogene
AU777770C (en) 1999-05-04 2005-11-10 Strakan International Limited Androgen glycosides and androgenic activity thereof
US7087592B1 (en) * 1999-08-23 2006-08-08 Entre Med, Inc. Compositions comprising purified 2-methoxyestradiol and methods of producing same
US20050192258A1 (en) * 2000-08-18 2005-09-01 Agoston Gregory E. Antiangiogenic agents
US7135581B2 (en) 2000-08-18 2006-11-14 Entremed, Inc. Antiangiogenic agents
US6995278B2 (en) * 2000-08-18 2006-02-07 Entre Med, Inc. Antiangiogenic agents
WO2002022645A2 (en) * 2000-09-14 2002-03-21 Accelerated Pharmaceuticals, Inc. Method of making 7alpha-methyl-11beta-methoxy estradiol and related compounds with estrogenic activity
US20030236439A1 (en) * 2002-01-30 2003-12-25 Gregory Agoston Non-steroidal analogs of 2-methoxyestradiol
EP1633367A2 (en) * 2003-05-28 2006-03-15 EntreMed, Inc. Antiangiogenic agents
US20070004689A1 (en) * 2004-03-12 2007-01-04 Agoston Gregory E Antiangiogenic agents
US7498322B2 (en) * 2004-03-12 2009-03-03 Entremed, Inc. Antiangiogenic agents
AU2005309455A1 (en) * 2004-11-29 2006-06-01 Entremed, Inc. A method of administering anti-angiogenic agents and a method of treating disease using same
US20070185069A1 (en) * 2005-11-14 2007-08-09 Plum Stacy M Anti-angiogenic activity of 2-methoxyestradiol in combination with anti-cancer agents
US20070176403A1 (en) * 2006-02-01 2007-08-02 Dennis Calderone Air adjustable seat
CA2646065C (en) * 2006-03-20 2014-01-14 Entremed, Inc. Disease modifying anti-arthritic activity of 2-methoxyestradiol
US20080234243A1 (en) * 2007-01-31 2008-09-25 Lavallee Theresa M Method of treating amyloidosis mediated diseases
JP6356218B2 (ja) * 2013-04-18 2018-07-11 シーアン リーバン ファーマシューティカル テクノロジー シーオー．， エルティーディー．Ｘｉ’Ａｎ Ｌｉｂａｎｇ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｔｅｃｈｎｏｌｏｇｙ Ｃｏ．， Ｌｔｄ． 抗腫瘍活性を有する７−α−［９−（４，４，５，５，５−ペンタフルオロペンチルスルフィニル）ノニル］−エストラ−１，３，５（１０）−トリエン−３，１７β−ジオールのエステル誘導体及びその調製方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB826790A (en) * 1957-05-07 1960-01-20 British Drug Houses Ltd Improvements in or relating to the preparation of cyclopentanophenanthrene compounds
DE1117113B (de) * 1959-12-05 1961-11-16 Schering Ag Verfahren zur Herstellung ª‡ú¼ ª‰-ungesaettigter Ketosteroide, die am ª‰-staendigen Kohlenstoffatom eine Methylgruppe tragen
US3018297A (en) * 1960-02-29 1962-01-23 Searle & Co 1, 3- and 1, 4-bisoxygenated estra-1, 3, 5(10)-trienes and intermediates
CH399447A (de) * 1961-04-14 1965-09-30 Ciba Geigy Verfahren zur Herstellung eines neuen Steroid-Hormon-Esters
US3226991A (en) * 1962-12-17 1966-01-04 United Carr Fastener Corp Indexing device for a rotary snap switch
FR5519M (da) * 1966-06-07 1967-11-06
US4147783A (en) * 1974-02-28 1979-04-03 Akzona Incorporated Oral pharmaceutical preparation
NL189235C (nl) * 1974-02-28 1993-02-16 Akzo Nv Werkwijze voor de bereiding van een oraal toe te dienen farmaceutisch preparaat met androgene werking.
US4098802A (en) * 1975-02-18 1978-07-04 Akzona Incorporated Oral pharmaceutical preparation having androgenic activity
NL7506407A (nl) * 1975-05-30 1976-12-02 Akzo Nv Werkwijze ter bereiding van een oraal werkzaam far- maceutisch preparaat.
DE2558076C2 (de) * 1975-12-19 1983-12-15 Schering AG, 1000 Berlin und 4709 Bergkamen Depot-Steroidester, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
NL7613248A (nl) * 1976-11-26 1978-05-30 Akzo Nv Werkwijze voor het bereiden van nieuwe steroid- esters.

Also Published As

Publication number Publication date
SE7713341L (sv) 1978-05-27
IE46092L (en) 1978-05-26
ES464504A1 (es) 1978-09-01
DE2752695A1 (de) 1978-06-01
US4329296A (en) 1982-05-11
US4212864A (en) 1980-07-15
US4307086A (en) 1981-12-22
CA1095895A (en) 1981-02-17
CH637143A5 (de) 1983-07-15
FR2373560B1 (da) 1980-08-22
FR2373560A1 (fr) 1978-07-07
DK146221B (da) 1983-08-01
BE861224A (fr) 1978-05-25
GB1593515A (en) 1981-07-15
US4307087A (en) 1981-12-22
DK146221C (da) 1984-01-09
JPS5384957A (en) 1978-07-26
NL7613248A (nl) 1978-05-30
US4312864A (en) 1982-01-26
IE46092B1 (en) 1983-02-23

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