JPS5259163A - Piperidine derivatives and preparation method thereof - Google Patents

Piperidine derivatives and preparation method thereof

Info

Publication number
JPS5259163A
JPS5259163A JP51133139A JP13313976A JPS5259163A JP S5259163 A JPS5259163 A JP S5259163A JP 51133139 A JP51133139 A JP 51133139A JP 13313976 A JP13313976 A JP 13313976A JP S5259163 A JPS5259163 A JP S5259163A
Authority
JP
Japan
Prior art keywords
preparation
piperidine derivatives
piperidine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP51133139A
Other languages
English (en)
Other versions
JPS6055509B2 (ja
Inventor
Gunaaru Furiibe Barutaa
Teiiru Matsukusu
Shiyutatsuha Kuruto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of JPS5259163A publication Critical patent/JPS5259163A/ja
Publication of JPS6055509B2 publication Critical patent/JPS6055509B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
JP51133139A 1975-11-07 1976-11-05 ピペリジン誘導体およびその製造法 Expired JPS6055509B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19752549999 DE2549999A1 (de) 1975-11-07 1975-11-07 Piperidin-derivate und verfahren zu ihrer herstellung
DE2549999.4 1975-11-07

Publications (2)

Publication Number Publication Date
JPS5259163A true JPS5259163A (en) 1977-05-16
JPS6055509B2 JPS6055509B2 (ja) 1985-12-05

Family

ID=5961166

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51133139A Expired JPS6055509B2 (ja) 1975-11-07 1976-11-05 ピペリジン誘導体およびその製造法

Country Status (20)

Country Link
US (1) US4243807A (ja)
JP (1) JPS6055509B2 (ja)
AT (1) AT352726B (ja)
BE (1) BE847973A (ja)
CA (1) CA1077942A (ja)
CH (3) CH624102A5 (ja)
DD (1) DD126942A5 (ja)
DE (1) DE2549999A1 (ja)
DK (1) DK494876A (ja)
FI (1) FI763148A7 (ja)
FR (1) FR2330678A1 (ja)
GB (1) GB1502050A (ja)
HU (1) HU171237B (ja)
IE (1) IE43866B1 (ja)
IT (1) IT1063618B (ja)
LU (1) LU76141A1 (ja)
NL (1) NL7612286A (ja)
SE (1) SE7612234L (ja)
SU (3) SU633473A3 (ja)
ZA (1) ZA766381B (ja)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA848275B (en) * 1983-12-28 1985-08-28 Degussa New piridine-2-ethers or pyridine-2-thioethers having a nitrogen-containing cycloaliphatic ring
US4556664A (en) * 1984-03-13 1985-12-03 Gunnar A. K. Aberg Method and composition for the treatment of cardiac arrhythmias
IE66332B1 (en) * 1986-11-03 1995-12-27 Novo Nordisk As Piperidine compounds and their preparation and use
US5231184A (en) * 1987-11-23 1993-07-27 Janssen Pharmaceutica N.V. Pridazinamine derivatives
US4822778A (en) * 1988-01-19 1989-04-18 Gunnar Aberg Membrane stabilizing phenoxy-piperidine compounds and pharmaceutical compositions employing such compounds
US5109002A (en) * 1989-09-08 1992-04-28 Du Pont Merck Pharmaceutical Company Antipsychotic 1-cycloalkylpiperidines
NZ239846A (en) * 1990-09-27 1994-11-25 Merck & Co Inc Sulphonamide derivatives and pharmaceutical compositions thereof
IL99537A (en) * 1990-09-27 1995-11-27 Merck & Co Inc Fibrinogen receptor antagonists and pharmaceutical compositions containing them
US5264420A (en) * 1990-09-27 1993-11-23 Merck & Co., Inc. Fibrinogen receptor antagonists
FR2667317B1 (fr) * 1990-10-02 1992-12-04 Synthelabo Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.
WO1992019595A1 (en) * 1991-05-07 1992-11-12 Merck & Co., Inc. Fibrinogen receptor antagonists
US5321034A (en) * 1991-05-07 1994-06-14 Merck & Co., Inc. Fibrinogen receptor antagonists
US5389631A (en) * 1991-10-29 1995-02-14 Merck & Co., Inc. Fibrinogen receptor antagonists
US5272158A (en) * 1991-10-29 1993-12-21 Merck & Co., Inc. Fibrinogen receptor antagonists
US5416099A (en) * 1991-10-29 1995-05-16 Merck & Co., Inc. Fibrinogen receptor antagonists
ATE188379T1 (de) * 1992-10-14 2000-01-15 Merck & Co Inc Fibrinogenrezeptor-antagonisten
US5358956A (en) * 1992-10-14 1994-10-25 Merck & Co., Inc. Fibrinogen receptor antagonists
US5648368A (en) * 1992-12-01 1997-07-15 Merck & Co., Inc. Fibrinogen receptor antagonists
US5441952A (en) * 1993-04-05 1995-08-15 Merck & Co., Inc. Fibrinogen receptor antagonists
US5334596A (en) * 1993-05-11 1994-08-02 Merck & Co., Inc. Fibrinogen receptor antagonists
US5397791A (en) * 1993-08-09 1995-03-14 Merck & Co., Inc. Fibrinogen receptor antagonists
US5821241A (en) * 1994-02-22 1998-10-13 Merck & Co., Inc. Fibrinogen receptor antagonists
US5719144A (en) * 1995-02-22 1998-02-17 Merck & Co., Inc. Fibrinogen receptor antagonists
US5750147A (en) 1995-06-07 1998-05-12 Emisphere Technologies, Inc. Method of solubilizing and encapsulating itraconazole
US6054586A (en) * 1995-09-28 2000-04-25 Kaken Pharmaceutical Co., Ltd. Process for the preparation of 4-methylenepiperidine
US5789421A (en) * 1995-10-26 1998-08-04 Merck & Co., Inc. Fibrinogen receptor antagonist
US5780480A (en) * 1996-02-28 1998-07-14 Merck & Co., Inc. Fibrinogen receptor antagonists
US5889023A (en) * 1996-05-10 1999-03-30 Merck & Co., Inc. Fibrinogen receptor antagonist
US5981584A (en) * 1997-02-06 1999-11-09 Merck & Co., Inc. Fibrinogen receptor antagonist prodrugs
EP2318362B1 (en) 2008-07-24 2013-09-25 Theravance, Inc. 3-(phenoxyphenylmethyl)pyrrolidine compounds
KR101656338B1 (ko) 2008-11-14 2016-09-09 세라밴스 바이오파마 알앤디 아이피, 엘엘씨 4­［2­（2­플루오로페녹시메틸）페닐］피페리딘 화합물의 결정형
US20100267743A1 (en) * 2009-04-15 2010-10-21 Stangeland Eric L 3-(phenoxypyrrolidin-3-yl-methyl)heteroaryl, 3-(phenylpyrrolidin-3-ylmethoxy)heteroaryl, and 3-(heteroarylpyrrolidin-3-ylmethoxy)heteroaryl compounds
AU2010273645B2 (en) 2009-07-13 2014-12-04 Theravance Biopharma R&D Ip, Llc 3-phenoxymethylpyrrolidine compounds
ES2495366T3 (es) 2009-07-21 2014-09-17 Theravance, Inc. Compuestos de 3-fenoximetilpirrolidina
EP2523945A1 (en) 2010-01-11 2012-11-21 Theravance, Inc. 1 - (2 - phenoxymethylphenyl) piperazine compounds as serotonin and norepinephrine reuptake inhibitors
ES2543064T3 (es) * 2010-03-22 2015-08-14 Theravance Biopharma R&D Ip, Llc Compuestos de 1-(2-fenoximetilheteroaril)piperidina y piperazina
ES2533434T3 (es) 2010-10-11 2015-04-10 Theravance Biopharma R&D Ip, Llc Inhibidores de la captación de la serotonina
US8501964B2 (en) 2010-12-03 2013-08-06 Theravance, Inc. Serotonin reuptake inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1268951A (en) * 1969-06-12 1972-03-29 Pfizer Ltd Phenoxy-amines
DE2245061A1 (de) * 1972-09-14 1974-03-28 Boehringer Mannheim Gmbh Derivate des adenins
DE2401254A1 (de) * 1974-01-11 1975-11-27 Boehringer Mannheim Gmbh Neue derivate von n hoch 6-substituierten adeninen
DE2550000A1 (de) * 1975-11-07 1977-05-12 Boehringer Mannheim Gmbh Neue purin-derivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
ZA766381B (en) 1977-10-26
JPS6055509B2 (ja) 1985-12-05
GB1502050A (en) 1978-02-22
DE2549999A1 (de) 1977-05-12
DK494876A (da) 1977-05-08
IT1063618B (it) 1985-02-11
US4243807A (en) 1981-01-06
LU76141A1 (ja) 1977-05-18
CH625788A5 (ja) 1981-10-15
FR2330678A1 (fr) 1977-06-03
SU662009A3 (ru) 1979-05-05
SU633473A3 (ru) 1978-11-15
DD126942A5 (ja) 1977-08-24
ATA823776A (de) 1979-03-15
BE847973A (fr) 1977-05-04
CH624102A5 (ja) 1981-07-15
CA1077942A (en) 1980-05-20
DE2549999C2 (ja) 1989-01-26
SE7612234L (sv) 1977-05-07
FI763148A7 (ja) 1977-05-08
CH627166A5 (ja) 1981-12-31
FR2330678B1 (ja) 1980-11-07
HU171237B (hu) 1977-12-28
SU867298A3 (ru) 1981-09-23
AT352726B (de) 1979-10-10
IE43866B1 (en) 1981-06-17
IE43866L (en) 1977-05-07
NL7612286A (nl) 1977-05-10

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