JPS5230885A - Crosslinked polymer consisting of collagen and mucopolysaccharide - Google Patents

Crosslinked polymer consisting of collagen and mucopolysaccharide

Info

Publication number
JPS5230885A
JPS5230885A JP51082872A JP8287276A JPS5230885A JP S5230885 A JPS5230885 A JP S5230885A JP 51082872 A JP51082872 A JP 51082872A JP 8287276 A JP8287276 A JP 8287276A JP S5230885 A JPS5230885 A JP S5230885A
Authority
JP
Japan
Prior art keywords
mucopolysaccharide
collagen
crosslinked polymer
polymer consisting
crosslinked
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP51082872A
Other languages
English (en)
Japanese (ja)
Other versions
JPS543779B2 (enrdf_load_stackoverflow
Inventor
Bui Yanasu Aioanisu
Eru Goodon Fuiritsupu
Fuangu Chiyoa
Eichi Shirubaa Furederitsuku
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
Original Assignee
Massachusetts Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Institute of Technology filed Critical Massachusetts Institute of Technology
Publication of JPS5230885A publication Critical patent/JPS5230885A/ja
Publication of JPS543779B2 publication Critical patent/JPS543779B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/06—At least partially resorbable materials
    • A61L17/10—At least partially resorbable materials containing macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005—Use of materials characterised by their function or physical properties
    • A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/06—Use of macromolecular materials
    • A61L33/062—Mixtures of macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00365—Proteins; Polypeptides; Degradation products thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Transplantation (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Laminated Bodies (AREA)
  • Sealing Material Composition (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
JP51082872A 1975-07-15 1976-07-12 Crosslinked polymer consisting of collagen and mucopolysaccharide Granted JPS5230885A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59611175A 1975-07-15 1975-07-15

Publications (2)

Publication Number Publication Date
JPS5230885A true JPS5230885A (en) 1977-03-08
JPS543779B2 JPS543779B2 (enrdf_load_stackoverflow) 1979-02-27

Family

ID=24386022

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51082872A Granted JPS5230885A (en) 1975-07-15 1976-07-12 Crosslinked polymer consisting of collagen and mucopolysaccharide

Country Status (5)

Country Link
JP (1) JPS5230885A (enrdf_load_stackoverflow)
CA (1) CA1087610A (enrdf_load_stackoverflow)
DE (1) DE2631908A1 (enrdf_load_stackoverflow)
FR (1) FR2318189A1 (enrdf_load_stackoverflow)
GB (1) GB1515963A (enrdf_load_stackoverflow)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58170720A (ja) * 1981-12-15 1983-10-07 コ−デイス・エウロパ・エヌ・ヴエ 抗凝固剤とタンパク質との複合体
JPS60222425A (ja) * 1984-02-24 1985-11-07 ザ・リ−ジエンツ・オブ・ザ・ユニバ−シテイ・オブ・カリフオルニア 創傷治癒剤
JPH01124465A (ja) * 1987-11-10 1989-05-17 Kanegafuchi Chem Ind Co Ltd 人工基底膜用組成物および人工基底膜を有する移植用デバイス
JPH01230366A (ja) * 1988-03-09 1989-09-13 Terumo Corp 細胞侵入性医用材料
JPH06507376A (ja) * 1990-07-27 1994-08-25 バース、ローレンス・サミュエル 組織の接合およびシール用組成物並びにその使用方法

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1085524B (it) * 1977-03-22 1985-05-28 Snam Progetti Materiali e fibre porose biocompatibili in grado di inglobare sostanze di interesse biologico e metodi per il loro ottenimento
US4378017A (en) 1980-03-21 1983-03-29 Kureha Kagaku Kogyo Kabushiki Kaisha Composite material of de-N-acetylated chitin and fibrous collagen
FR2517315B1 (fr) * 1981-11-30 1985-12-20 Tech Cuir Centre Procede de preparation de formes nouvelles de collagene, natif ou dereticule, a structure helicoidale preservee, associees a des mucopolysaccharides et leurs applications notamment dans les domaines cosmetologiques, pharmaceutiques, analytiques et autres
US4526714A (en) * 1982-12-13 1985-07-02 Cordis Europa N.V. Conjugates of anticoagulant and protein
US4678671A (en) * 1981-12-15 1987-07-07 Cordis Europa N.V. Conjugates of anticoagulant and protein
CA1213520A (en) * 1982-03-17 1986-11-04 Abe Widra Hydrophilic biopolymeric copolyelectrolytes, and biodegradable dressings comprising same
JPS58180162A (ja) * 1982-04-19 1983-10-21 株式会社高研 抗血栓性医用材料
GB2148901A (en) * 1983-10-04 1985-06-05 Johnson & Johnson Protein/polysaccharide complexes
CA1238043A (en) * 1983-12-15 1988-06-14 Endre A. Balazs Water insoluble preparations of hyaluronic acid and processes therefor
JPS60130601A (ja) * 1983-12-15 1985-07-12 バイオマトリツクス，インコ−ポレイテツド ヒアルロン酸水不溶性組成物の製法
US4500676A (en) * 1983-12-15 1985-02-19 Biomatrix, Inc. Hyaluronate modified polymeric articles
US4487865A (en) * 1983-12-15 1984-12-11 Biomatrix, Inc. Polymeric articles modified with hyaluronate
SE442820B (sv) * 1984-06-08 1986-02-03 Pharmacia Ab Gel av tverbunden hyaluronsyra for anvendning som glaskroppssubstitut
SE456346B (sv) * 1984-07-23 1988-09-26 Pharmacia Ab Gel for att forhindra adhesion mellan kroppsvevnader och sett for dess framstellning
US4582865A (en) * 1984-12-06 1986-04-15 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
FR2585576B1 (fr) * 1985-07-30 1992-01-03 Bioetica Sa Produit de remplacement de la matrice osseuse favorisant l'osteogenese
EP0246638A3 (en) * 1986-05-23 1989-03-15 Cordis Corporation Biologically modified synthetic grafts
US5735902A (en) * 1987-07-20 1998-04-07 Regen Biologics, Inc. Hand implant device
US5263984A (en) * 1987-07-20 1993-11-23 Regen Biologics, Inc. Prosthetic ligaments
US5681353A (en) * 1987-07-20 1997-10-28 Regen Biologics, Inc. Meniscal augmentation device
US4880429A (en) * 1987-07-20 1989-11-14 Stone Kevin R Prosthetic meniscus
US5306311A (en) * 1987-07-20 1994-04-26 Regen Corporation Prosthetic articular cartilage
US5007934A (en) * 1987-07-20 1991-04-16 Regen Corporation Prosthetic meniscus
US5108438A (en) * 1989-03-02 1992-04-28 Regen Corporation Prosthetic intervertebral disc
US5645591A (en) * 1990-05-29 1997-07-08 Stryker Corporation Synthetic bone matrix
US5990096A (en) * 1990-09-18 1999-11-23 Hyal Pharmaceutical Corporation Formulations containing hyaluronic acid
US5910489A (en) * 1990-09-18 1999-06-08 Hyal Pharmaceutical Corporation Topical composition containing hyaluronic acid and NSAIDS
US5824658A (en) * 1990-09-18 1998-10-20 Hyal Pharmaceutical Corporation Topical composition containing hyaluronic acid and NSAIDS
CA2061703C (en) * 1992-02-20 2002-07-02 Rudolf E. Falk Formulations containing hyaluronic acid
US5977088A (en) * 1991-07-03 1999-11-02 Hyal Pharmaceutical Corporation Formulations containing hyaluronic acid
US6103704A (en) * 1991-07-03 2000-08-15 Hyal Pharmaceutical Corporation Therapeutic methods using hyaluronic acid
US5792753A (en) * 1991-07-03 1998-08-11 Hyal Pharmaceutical Corporation Compositions comprising hyaluronic acid and prostaglandin-synthesis-inhibiting drugs
US6218373B1 (en) 1992-02-20 2001-04-17 Hyal Pharmaceutical Corporation Formulations containing hyaluronic acid
US5767106A (en) * 1992-02-21 1998-06-16 Hyal Pharmaceutical Corporation Treatment of disease and conditions associated with macrophage infiltration
DE4425776C2 (de) * 1994-07-13 2002-08-29 Britta Hofmann Verfahren zur Herstellung eines verbesserten Kollagentransplantats mit aufgelockerter Struktur
EP0698396B1 (en) * 1994-08-12 2001-12-12 Meadox Medicals, Inc. Vascular graft impregnated with a heparin-containing collagen sealant
DE19630879A1 (de) * 1996-07-31 1998-02-05 Hanno Lutz Prof Dr Baumann Verfahren zur Herstellung blutverträglicher Werkstoffe durch Oberflächenbeschichtung von synthetischen Polymeren mit wasserlöslichen Substanzen aus natürlichen oder modifizierten Oligo- und Polysacchariden über kovalente Bindungen
JP2004512145A (ja) * 2000-10-31 2004-04-22 デピュイ・アクロメッド・インコーポレイテッド 骨および軟骨の修復用の鉱物質化したコラーゲン−多糖類型基質
US7309359B2 (en) 2003-08-21 2007-12-18 Warsaw Orthopedic, Inc. Allogenic/xenogenic implants and methods for augmenting or repairing intervertebral discs
KR101162191B1 (ko) 2004-04-15 2012-07-05 넥실리스 아게 뼈 형성용 기질 복합재, 그의 제조 방법 및 그로 코팅된 조직 공학용 지지체
DE102005017845A1 (de) 2005-04-18 2006-10-19 Lohmann & Rauscher Gmbh & Co. Kg Autosterile, antiseptische Kollagenzubereitungen, ihre Verwendung und Verfahren zu ihrer Herstellung
US8399619B2 (en) 2006-06-30 2013-03-19 Warsaw Orthopedic, Inc. Injectable collagen material
US8118779B2 (en) 2006-06-30 2012-02-21 Warsaw Orthopedic, Inc. Collagen delivery device
CN100457989C (zh) * 2006-11-04 2009-02-04 青岛大学 高强度海藻酸/明胶共混纤维的制备方法
CN103301510B (zh) * 2013-06-20 2014-12-24 孙文善 一种针灸埋植材料
CN112704768A (zh) * 2020-11-30 2021-04-27 山东大学 一种硫酸软骨素修饰的胶原蛋白/聚己内酯血管修复支架及其制备方法与应用
CN117298327B (zh) * 2023-11-15 2024-10-01 北京帝康医药投资管理有限公司 一种止血微球颗粒及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1491218C3 (de) * 1963-06-15 1973-01-04 Spofa Sdruzheni Podniku Pro Zdravotnickou Vyrobu, Prag Blutgefäßprothese und Verfahren zur Herstellung derselben
US3527225A (en) * 1964-09-29 1970-09-08 David F Smith Resorbable surgical sutures from fibrous proteins
FR2236539A1 (en) * 1973-07-13 1975-02-07 Ladialas Robert Biological polymeric membrane prepn. - by depolymerising elastin and then, copolymerising the peptides with gelatin, collagen etc.

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58170720A (ja) * 1981-12-15 1983-10-07 コ−デイス・エウロパ・エヌ・ヴエ 抗凝固剤とタンパク質との複合体
JPS60222425A (ja) * 1984-02-24 1985-11-07 ザ・リ−ジエンツ・オブ・ザ・ユニバ−シテイ・オブ・カリフオルニア 創傷治癒剤
JPH01124465A (ja) * 1987-11-10 1989-05-17 Kanegafuchi Chem Ind Co Ltd 人工基底膜用組成物および人工基底膜を有する移植用デバイス
JPH01230366A (ja) * 1988-03-09 1989-09-13 Terumo Corp 細胞侵入性医用材料
JPH06507376A (ja) * 1990-07-27 1994-08-25 バース、ローレンス・サミュエル 組織の接合およびシール用組成物並びにその使用方法

Also Published As

Publication number Publication date
GB1515963A (en) 1978-06-28
JPS543779B2 (enrdf_load_stackoverflow) 1979-02-27
DE2631908A1 (de) 1977-02-10
FR2318189B1 (enrdf_load_stackoverflow) 1980-08-01
DE2631908C2 (enrdf_load_stackoverflow) 1988-10-20
CA1087610A (en) 1980-10-14
FR2318189A1 (fr) 1977-02-11

Similar Documents

Publication Publication Date Title
JPS5230885A (en) Crosslinked polymer consisting of collagen and mucopolysaccharide
JPS52994A (en) Imide grouppcontaining crosslinked polymer and preparation thereof
GB1551163A (en) Non-antigenic collagen and articles of manufacture
PH13797A (en) Single place extrusion of acrylic polymer and water
AR213619A1 (es) Polimero de ortoester y su preparacion
JPS51137791A (en) Waterrdispersing polymer and coating method
GB1556233A (en) Branched block copolymers and their manufacture
JPS5251437A (en) Bridge formation polymer powder and laminate
JPS5212153A (en) Production of fuluorenone derivatives monomer and polymer thereof
JPS5268292A (en) Poly*acrylateesulfon*and preparation thereof
IL48690A0 (en) Blood compatible polymers and their use
JPS5440868A (en) Methylpentene polymer film and manufacture
JPS5260892A (en) Bis*allyllcarbonate* composition and polymer therefrom
AU503869B2 (en) Extrusion of crosslinked polymers
JPS5223152A (en) Acrylate polymer composition and curing composition
JPS5277054A (en) Production of bissimidyl derivatives and corresponding closed ring derivatives and crosslinked polymer obtained from the same
JPS5483055A (en) Solid polyaminoester polymer composition and manufacture
GB1556234A (en) Branched block copolymers and their manufacture
JPS52107086A (en) Preparation of modified polymer and use thereof
JPS5516082A (en) Manufacture of polyynnvinylpyrrolidonee2 denatured polymer and its use
JPS529092A (en) Polymer crosslinkage poly*vinylbenzyl*nitrogenncontaining gel resin and prparation thereof
GB1548294A (en) Polymer process and paint
JPS5284300A (en) Ketone and sulfone polymer
JPS52993A (en) Crosslinkagable polymer and preparation thereof
AU1779176A (en) Polymers and polymer blends