GB1515963A - Crosslinked collagen-mucopolysaccharide composite materials - Google Patents

Crosslinked collagen-mucopolysaccharide composite materials

Info

Publication number
GB1515963A
GB1515963A GB2835976A GB2835976A GB1515963A GB 1515963 A GB1515963 A GB 1515963A GB 2835976 A GB2835976 A GB 2835976A GB 2835976 A GB2835976 A GB 2835976A GB 1515963 A GB1515963 A GB 1515963A
Authority
GB
United Kingdom
Prior art keywords
mucopolysaccharide
cross
collagen
sulphate
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2835976A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
Original Assignee
Massachusetts Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Institute of Technology filed Critical Massachusetts Institute of Technology
Publication of GB1515963A publication Critical patent/GB1515963A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/06—At least partially resorbable materials
    • A61L17/10—At least partially resorbable materials containing macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005—Use of materials characterised by their function or physical properties
    • A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/06—Use of macromolecular materials
    • A61L33/062—Mixtures of macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00365—Proteins; Polypeptides; Degradation products thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Molecular Biology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Biophysics (AREA)
  • Materials For Medical Uses (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Laminated Bodies (AREA)
  • Sealing Material Composition (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GB2835976A 1975-07-15 1976-07-08 Crosslinked collagen-mucopolysaccharide composite materials Expired GB1515963A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59611175A 1975-07-15 1975-07-15

Publications (1)

Publication Number Publication Date
GB1515963A true GB1515963A (en) 1978-06-28

Family

ID=24386022

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2835976A Expired GB1515963A (en) 1975-07-15 1976-07-08 Crosslinked collagen-mucopolysaccharide composite materials

Country Status (5)

Country Link
JP (1) JPS5230885A (enrdf_load_stackoverflow)
CA (1) CA1087610A (enrdf_load_stackoverflow)
DE (1) DE2631908A1 (enrdf_load_stackoverflow)
FR (1) FR2318189A1 (enrdf_load_stackoverflow)
GB (1) GB1515963A (enrdf_load_stackoverflow)

Cited By (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4378017A (en) 1980-03-21 1983-03-29 Kureha Kagaku Kogyo Kabushiki Kaisha Composite material of de-N-acetylated chitin and fibrous collagen
GB2148901A (en) * 1983-10-04 1985-06-05 Johnson & Johnson Protein/polysaccharide complexes
US4526714A (en) * 1982-12-13 1985-07-02 Cordis Europa N.V. Conjugates of anticoagulant and protein
US4634762A (en) * 1981-12-15 1987-01-06 Sentron V.O.F. Conjugates of anticoagulant and protein
US4678671A (en) * 1981-12-15 1987-07-07 Cordis Europa N.V. Conjugates of anticoagulant and protein
WO1989000413A1 (en) * 1987-07-20 1989-01-26 Stone Kevin R Prosthetic meniscus
WO1990009769A1 (en) * 1989-03-02 1990-09-07 Regen Corporation Prosthetic meniscus
WO1991018558A1 (en) * 1990-05-29 1991-12-12 Creative Biomolecules, Inc. Synthetic bone matrix
US5108438A (en) * 1989-03-02 1992-04-28 Regen Corporation Prosthetic intervertebral disc
US5263984A (en) * 1987-07-20 1993-11-23 Regen Biologics, Inc. Prosthetic ligaments
US5306311A (en) * 1987-07-20 1994-04-26 Regen Corporation Prosthetic articular cartilage
US5681353A (en) * 1987-07-20 1997-10-28 Regen Biologics, Inc. Meniscal augmentation device
US5735902A (en) * 1987-07-20 1998-04-07 Regen Biologics, Inc. Hand implant device
WO2006111347A1 (de) 2005-04-18 2006-10-26 Lohmann & Rauscher Gmbh & Co Kg. Autosterile, antiseptische kollagenzubereitungen, ihre verwendung und verfahren zu ihrer herstelllung
EP1337266A4 (en) * 2000-10-31 2006-11-02 Depuy Spine Inc MINERALIZED COLLAGEN POLYSACCHARIDE MATRIX FOR THE RECONSTRUCTION OF BONES AND CARTILES
US7309359B2 (en) 2003-08-21 2007-12-18 Warsaw Orthopedic, Inc. Allogenic/xenogenic implants and methods for augmenting or repairing intervertebral discs
CN100457989C (zh) * 2006-11-04 2009-02-04 青岛大学 高强度海藻酸/明胶共混纤维的制备方法
US8118779B2 (en) 2006-06-30 2012-02-21 Warsaw Orthopedic, Inc. Collagen delivery device
US8399619B2 (en) 2006-06-30 2013-03-19 Warsaw Orthopedic, Inc. Injectable collagen material
CN112704768A (zh) * 2020-11-30 2021-04-27 山东大学 一种硫酸软骨素修饰的胶原蛋白/聚己内酯血管修复支架及其制备方法与应用
CN117298327A (zh) * 2023-11-15 2023-12-29 北京帝康医药投资管理有限公司 一种止血微球颗粒及其制备方法和应用

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1085524B (it) * 1977-03-22 1985-05-28 Snam Progetti Materiali e fibre porose biocompatibili in grado di inglobare sostanze di interesse biologico e metodi per il loro ottenimento
FR2517315B1 (fr) * 1981-11-30 1985-12-20 Tech Cuir Centre Procede de preparation de formes nouvelles de collagene, natif ou dereticule, a structure helicoidale preservee, associees a des mucopolysaccharides et leurs applications notamment dans les domaines cosmetologiques, pharmaceutiques, analytiques et autres
CA1213520A (en) * 1982-03-17 1986-11-04 Abe Widra Hydrophilic biopolymeric copolyelectrolytes, and biodegradable dressings comprising same
JPS58180162A (ja) * 1982-04-19 1983-10-21 株式会社高研 抗血栓性医用材料
JPS60130601A (ja) * 1983-12-15 1985-07-12 バイオマトリツクス，インコ−ポレイテツド ヒアルロン酸水不溶性組成物の製法
US4500676A (en) * 1983-12-15 1985-02-19 Biomatrix, Inc. Hyaluronate modified polymeric articles
CA1238043A (en) * 1983-12-15 1988-06-14 Endre A. Balazs Water insoluble preparations of hyaluronic acid and processes therefor
US4487865A (en) * 1983-12-15 1984-12-11 Biomatrix, Inc. Polymeric articles modified with hyaluronate
US4745098A (en) * 1984-02-24 1988-05-17 The Regents Of The University Of California Compositions and method for improving wound healing
SE442820B (sv) * 1984-06-08 1986-02-03 Pharmacia Ab Gel av tverbunden hyaluronsyra for anvendning som glaskroppssubstitut
SE456346B (sv) * 1984-07-23 1988-09-26 Pharmacia Ab Gel for att forhindra adhesion mellan kroppsvevnader och sett for dess framstellning
US4582865A (en) * 1984-12-06 1986-04-15 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
FR2585576B1 (fr) * 1985-07-30 1992-01-03 Bioetica Sa Produit de remplacement de la matrice osseuse favorisant l'osteogenese
EP0246638A3 (en) * 1986-05-23 1989-03-15 Cordis Corporation Biologically modified synthetic grafts
JPH01124465A (ja) * 1987-11-10 1989-05-17 Kanegafuchi Chem Ind Co Ltd 人工基底膜用組成物および人工基底膜を有する移植用デバイス
JPH0622579B2 (ja) * 1988-03-09 1994-03-30 テルモ株式会社 細胞侵入性医用材料
US5292362A (en) * 1990-07-27 1994-03-08 The Trustees Of Columbia University In The City Of New York Tissue bonding and sealing composition and method of using the same
US5824658A (en) * 1990-09-18 1998-10-20 Hyal Pharmaceutical Corporation Topical composition containing hyaluronic acid and NSAIDS
CA2061703C (en) * 1992-02-20 2002-07-02 Rudolf E. Falk Formulations containing hyaluronic acid
US5990096A (en) * 1990-09-18 1999-11-23 Hyal Pharmaceutical Corporation Formulations containing hyaluronic acid
US5910489A (en) * 1990-09-18 1999-06-08 Hyal Pharmaceutical Corporation Topical composition containing hyaluronic acid and NSAIDS
US5977088A (en) * 1991-07-03 1999-11-02 Hyal Pharmaceutical Corporation Formulations containing hyaluronic acid
US5792753A (en) * 1991-07-03 1998-08-11 Hyal Pharmaceutical Corporation Compositions comprising hyaluronic acid and prostaglandin-synthesis-inhibiting drugs
US6103704A (en) * 1991-07-03 2000-08-15 Hyal Pharmaceutical Corporation Therapeutic methods using hyaluronic acid
US6218373B1 (en) 1992-02-20 2001-04-17 Hyal Pharmaceutical Corporation Formulations containing hyaluronic acid
US5767106A (en) * 1992-02-21 1998-06-16 Hyal Pharmaceutical Corporation Treatment of disease and conditions associated with macrophage infiltration
DE4425776C2 (de) * 1994-07-13 2002-08-29 Britta Hofmann Verfahren zur Herstellung eines verbesserten Kollagentransplantats mit aufgelockerter Struktur
EP0698396B1 (en) * 1994-08-12 2001-12-12 Meadox Medicals, Inc. Vascular graft impregnated with a heparin-containing collagen sealant
DE19630879A1 (de) * 1996-07-31 1998-02-05 Hanno Lutz Prof Dr Baumann Verfahren zur Herstellung blutverträglicher Werkstoffe durch Oberflächenbeschichtung von synthetischen Polymeren mit wasserlöslichen Substanzen aus natürlichen oder modifizierten Oligo- und Polysacchariden über kovalente Bindungen
ATE435668T1 (de) 2004-04-15 2009-07-15 Nexilis Ag Osteogenes matrixkomposit, verfahren zu dessen herstellung sowie implantat und scaffold für das tissue engineering mit einer beschichtung aus einem osteogenen matrixkomposit
CN103301510B (zh) * 2013-06-20 2014-12-24 孙文善 一种针灸埋植材料

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1491218C3 (de) * 1963-06-15 1973-01-04 Spofa Sdruzheni Podniku Pro Zdravotnickou Vyrobu, Prag Blutgefäßprothese und Verfahren zur Herstellung derselben
US3527225A (en) * 1964-09-29 1970-09-08 David F Smith Resorbable surgical sutures from fibrous proteins
FR2236539A1 (en) * 1973-07-13 1975-02-07 Ladialas Robert Biological polymeric membrane prepn. - by depolymerising elastin and then, copolymerising the peptides with gelatin, collagen etc.

Cited By (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4378017A (en) 1980-03-21 1983-03-29 Kureha Kagaku Kogyo Kabushiki Kaisha Composite material of de-N-acetylated chitin and fibrous collagen
US4634762A (en) * 1981-12-15 1987-01-06 Sentron V.O.F. Conjugates of anticoagulant and protein
US4678671A (en) * 1981-12-15 1987-07-07 Cordis Europa N.V. Conjugates of anticoagulant and protein
US4526714A (en) * 1982-12-13 1985-07-02 Cordis Europa N.V. Conjugates of anticoagulant and protein
GB2148901A (en) * 1983-10-04 1985-06-05 Johnson & Johnson Protein/polysaccharide complexes
US4880429A (en) * 1987-07-20 1989-11-14 Stone Kevin R Prosthetic meniscus
US5735903A (en) * 1987-07-20 1998-04-07 Li; Shu-Tung Meniscal augmentation device
WO1989000413A1 (en) * 1987-07-20 1989-01-26 Stone Kevin R Prosthetic meniscus
US5007934A (en) * 1987-07-20 1991-04-16 Regen Corporation Prosthetic meniscus
US6042610A (en) * 1987-07-20 2000-03-28 Regen Biologics, Inc. Meniscal augmentation device
US5735902A (en) * 1987-07-20 1998-04-07 Regen Biologics, Inc. Hand implant device
US5263984A (en) * 1987-07-20 1993-11-23 Regen Biologics, Inc. Prosthetic ligaments
US5306311A (en) * 1987-07-20 1994-04-26 Regen Corporation Prosthetic articular cartilage
US5624463A (en) * 1987-07-20 1997-04-29 Regen Biologics, Inc. Prosthetic articular cartilage
US5681353A (en) * 1987-07-20 1997-10-28 Regen Biologics, Inc. Meniscal augmentation device
WO1990009769A1 (en) * 1989-03-02 1990-09-07 Regen Corporation Prosthetic meniscus
US5108438A (en) * 1989-03-02 1992-04-28 Regen Corporation Prosthetic intervertebral disc
WO1991018558A1 (en) * 1990-05-29 1991-12-12 Creative Biomolecules, Inc. Synthetic bone matrix
US6468308B1 (en) 1990-05-29 2002-10-22 Stryker Corporation Synthetic bone matrix
US6605117B2 (en) 1990-05-29 2003-08-12 Stryker Corporation Synthetic bone matrix
EP1337266A4 (en) * 2000-10-31 2006-11-02 Depuy Spine Inc MINERALIZED COLLAGEN POLYSACCHARIDE MATRIX FOR THE RECONSTRUCTION OF BONES AND CARTILES
US7309359B2 (en) 2003-08-21 2007-12-18 Warsaw Orthopedic, Inc. Allogenic/xenogenic implants and methods for augmenting or repairing intervertebral discs
US9011543B2 (en) 2003-08-21 2015-04-21 Warsaw Orthopedic, Inc. Methods for augmenting or repairing intervertebral discs with allogenic/xenogenic implants
WO2006111347A1 (de) 2005-04-18 2006-10-26 Lohmann & Rauscher Gmbh & Co Kg. Autosterile, antiseptische kollagenzubereitungen, ihre verwendung und verfahren zu ihrer herstelllung
US7956094B2 (en) 2005-04-18 2011-06-07 Lohmann & Rauscher Gmbh & Co. Kg Self-sterilized, antiseptic collagen preparations, their use and methods for producing them
US8118779B2 (en) 2006-06-30 2012-02-21 Warsaw Orthopedic, Inc. Collagen delivery device
US8399619B2 (en) 2006-06-30 2013-03-19 Warsaw Orthopedic, Inc. Injectable collagen material
CN100457989C (zh) * 2006-11-04 2009-02-04 青岛大学 高强度海藻酸/明胶共混纤维的制备方法
CN112704768A (zh) * 2020-11-30 2021-04-27 山东大学 一种硫酸软骨素修饰的胶原蛋白/聚己内酯血管修复支架及其制备方法与应用
CN117298327A (zh) * 2023-11-15 2023-12-29 北京帝康医药投资管理有限公司 一种止血微球颗粒及其制备方法和应用

Also Published As

Publication number Publication date
FR2318189A1 (fr) 1977-02-11
JPS5230885A (en) 1977-03-08
CA1087610A (en) 1980-10-14
DE2631908C2 (enrdf_load_stackoverflow) 1988-10-20
DE2631908A1 (de) 1977-02-10
FR2318189B1 (enrdf_load_stackoverflow) 1980-08-01
JPS543779B2 (enrdf_load_stackoverflow) 1979-02-27

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Legal Events

Date Code Title Description
PS Patent sealed
PE20 Patent expired after termination of 20 years

Effective date: 19960707