JPS50129590A - - Google Patents

Info

Publication number
JPS50129590A
JPS50129590A JP50023775A JP2377575A JPS50129590A JP S50129590 A JPS50129590 A JP S50129590A JP 50023775 A JP50023775 A JP 50023775A JP 2377575 A JP2377575 A JP 2377575A JP S50129590 A JPS50129590 A JP S50129590A
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP50023775A
Other languages
Japanese (ja)
Other versions
JPS625919B2 (US06420036-20020716-C00037.png
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH269374A external-priority patent/CH601310A5/de
Priority claimed from CH776674A external-priority patent/CH610584A5/de
Application filed filed Critical
Publication of JPS50129590A publication Critical patent/JPS50129590A/ja
Publication of JPS625919B2 publication Critical patent/JPS625919B2/ja
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C313/00Sulfinic acids; Sulfenic acids; Halides, esters or anhydrides thereof; Amides of sulfinic or sulfenic acids, i.e. compounds having singly-bound oxygen atoms of sulfinic or sulfenic groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C313/02Sulfinic acids; Derivatives thereof
    • C07C313/04Sulfinic acids; Esters thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C07D205/095Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP50023775A 1974-02-26 1975-02-26 Expired JPS625919B2 (US06420036-20020716-C00037.png)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH269374A CH601310A5 (en) 1974-02-26 1974-02-26 7-Amino-3-hydroxy-2(or 3)-cephem-4-carboxylic acid derivs prepn
CH776674A CH610584A5 (en) 1974-02-26 1974-06-05 Process for the preparation of 2-(3-amino-2-oxo-4-sulphonylthio-1- azetidinyl)-3-methylenebutyric acid derivatives
CH1100074 1974-08-12

Publications (2)

Publication Number Publication Date
JPS50129590A true JPS50129590A (US06420036-20020716-C00037.png) 1975-10-13
JPS625919B2 JPS625919B2 (US06420036-20020716-C00037.png) 1987-02-07

Family

ID=27173851

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50023775A Expired JPS625919B2 (US06420036-20020716-C00037.png) 1974-02-26 1975-02-26

Country Status (21)

Country Link
JP (1) JPS625919B2 (US06420036-20020716-C00037.png)
AR (1) AR208538A1 (US06420036-20020716-C00037.png)
AT (2) AT337362B (US06420036-20020716-C00037.png)
AU (1) AU498131B2 (US06420036-20020716-C00037.png)
BE (1) BE825919A (US06420036-20020716-C00037.png)
BG (1) BG26201A3 (US06420036-20020716-C00037.png)
CA (2) CA1059988A (US06420036-20020716-C00037.png)
DD (1) DD117074A5 (US06420036-20020716-C00037.png)
DE (1) DE2506330A1 (US06420036-20020716-C00037.png)
DK (2) DK73475A (US06420036-20020716-C00037.png)
ES (2) ES435110A1 (US06420036-20020716-C00037.png)
FI (1) FI66389C (US06420036-20020716-C00037.png)
FR (1) FR2261761B1 (US06420036-20020716-C00037.png)
GB (1) GB1503581A (US06420036-20020716-C00037.png)
HU (1) HU175212B (US06420036-20020716-C00037.png)
IE (1) IE40695B1 (US06420036-20020716-C00037.png)
IL (1) IL46699A (US06420036-20020716-C00037.png)
NL (1) NL7502292A (US06420036-20020716-C00037.png)
NO (1) NO750625L (US06420036-20020716-C00037.png)
NZ (1) NZ176623A (US06420036-20020716-C00037.png)
SE (3) SE431652B (US06420036-20020716-C00037.png)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5139659A (US06420036-20020716-C00037.png) * 1974-08-02 1976-04-02 Farmaceutici Italia
JPS5198265A (US06420036-20020716-C00037.png) * 1975-02-17 1976-08-30
JPS59161387A (ja) * 1983-03-04 1984-09-12 Otsuka Chem Co Ltd セファロスポリン化合物の製造法
JPS59228854A (ja) * 1983-06-08 1984-12-22 真井 康博 薬液収納兼即効注出器
JPS61178961A (ja) * 1985-02-01 1986-08-11 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
WO1992016532A1 (en) * 1991-03-13 1992-10-01 Otsuka Kagaku Kabushiki Kaisha HALOGENATED β-LACTAM COMPOUND AND PRODUCTION OF 3-HYDROXYCEPHEM DERIVATIVE THEREFROM
JP2006507289A (ja) * 2002-11-01 2006-03-02 オーキッド ケミカルズ アンド ファーマシューティカルズ リミテッド 改良されたクロロメチルセフェム誘導体調製方法

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1136132A (en) * 1975-02-17 1982-11-23 Teruji Tsuji Cyclization to form cephem ring and intermediates therefor
AT342197B (de) * 1975-02-20 1978-03-28 Ciba Geigy Ag Neues verfahren zur herstellung von 3-cephemverbindungen
US4029645A (en) * 1975-11-17 1977-06-14 E. R. Squibb & Sons, Inc. Mercury intermediates useful in the preparation of 2-alkoxy cephalosporins
JPS60126263A (ja) * 1983-12-12 1985-07-05 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
JPS60237061A (ja) * 1984-05-08 1985-11-25 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
GB2152497B (en) * 1983-11-28 1987-08-05 Otsuka Kagaku Kk Process for the preparation of azetidinone derivatives
JPS60115562A (ja) * 1983-11-28 1985-06-22 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
DE3725375A1 (de) * 1987-07-31 1989-02-09 Bayer Ag Stabile oxapenem-3-carbonsaeuren
US9708357B2 (en) 2011-12-20 2017-07-18 Riboscience, LLC 4′-azido, 3′-fluoro substituted nucleoside derivatives as inhibitors of HCV RNA replication
ES2636448T3 (es) 2011-12-20 2017-10-05 Riboscience Llc Derivados de nucleósido 2',4'-difluoro-2'-metil sustituidos como inhibidores de la replicación del ARN del VHC
PE20160119A1 (es) 2013-05-16 2016-02-24 Riboscience Llc Derivados de nucleosido 4'-azido, 3'-desoxi-3'-fluoro sustituido
US20180200280A1 (en) 2013-05-16 2018-07-19 Riboscience Llc 4'-Fluoro-2'-Methyl Substituted Nucleoside Derivatives as Inhibitors of HCV RNA Replication
WO2014186637A1 (en) 2013-05-16 2014-11-20 Riboscience Llc 4'-fluor0-2'-methyl substituted nucleoside derivatives
JP7299897B2 (ja) 2017-09-21 2023-06-28 リボサイエンス リミティド ライアビリティ カンパニー Hcvのrna複製阻害剤としての4’-フルオロ-2’-メチル置換ヌクレオシド誘導体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2230372A1 (de) * 1972-06-21 1973-01-11 Fujisawa Pharmaceutical Co Verfahren zur herstellung von oxidierten penam-derivaten
AR206201A1 (es) * 1972-06-29 1976-07-07 Ciba Geigy Ag Procedimiento para la obtencion de compuestos de acido 7beta-amino-3-cefem-3-01-4-carboxilico0-substituidos
SE428022B (sv) * 1972-06-29 1983-05-30 Ciba Geigy Ag 7beta-amino-cefam-3-on-4-karboxylsyraforeningar till anvendning for framstellning av cefalosporinderivat

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5139659A (US06420036-20020716-C00037.png) * 1974-08-02 1976-04-02 Farmaceutici Italia
JPS6028839B2 (ja) * 1974-08-02 1985-07-06 ソシエタ・フオルマセウチシ・イタリア・ソシエタ・ペル・アツイオーニ アゼチジノン誘導体の製法
JPS5198265A (US06420036-20020716-C00037.png) * 1975-02-17 1976-08-30
JPS59161387A (ja) * 1983-03-04 1984-09-12 Otsuka Chem Co Ltd セファロスポリン化合物の製造法
JPS59228854A (ja) * 1983-06-08 1984-12-22 真井 康博 薬液収納兼即効注出器
JPH0130500B2 (US06420036-20020716-C00037.png) * 1983-06-08 1989-06-20 Yasuhiro Mai
JPS61178961A (ja) * 1985-02-01 1986-08-11 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
JPH0546334B2 (US06420036-20020716-C00037.png) * 1985-02-01 1993-07-13 Otsuka Kagaku Kk
WO1992016532A1 (en) * 1991-03-13 1992-10-01 Otsuka Kagaku Kabushiki Kaisha HALOGENATED β-LACTAM COMPOUND AND PRODUCTION OF 3-HYDROXYCEPHEM DERIVATIVE THEREFROM
JP2006507289A (ja) * 2002-11-01 2006-03-02 オーキッド ケミカルズ アンド ファーマシューティカルズ リミテッド 改良されたクロロメチルセフェム誘導体調製方法

Also Published As

Publication number Publication date
JPS625919B2 (US06420036-20020716-C00037.png) 1987-02-07
SE438855B (sv) 1985-05-13
SE7501317L (US06420036-20020716-C00037.png) 1975-08-27
CA1080713A (en) 1980-07-01
SE7807811L (sv) 1978-07-13
CA1059988A (en) 1979-08-07
FI750503A (US06420036-20020716-C00037.png) 1975-08-27
ATA28178A (de) 1978-10-15
ATA108275A (de) 1976-10-15
AU7849875A (en) 1976-08-26
NL7502292A (nl) 1975-08-28
FI66389C (fi) 1984-10-10
FR2261761B1 (US06420036-20020716-C00037.png) 1978-08-18
AT337362B (de) 1977-06-27
GB1503581A (en) 1978-03-15
SE7807810L (sv) 1978-07-13
IE40695B1 (en) 1979-08-01
IL46699A0 (en) 1975-04-25
HU175212B (hu) 1980-06-28
AR208538A1 (es) 1977-02-15
FI66389B (fi) 1984-06-29
FR2261761A1 (US06420036-20020716-C00037.png) 1975-09-19
DK73475A (US06420036-20020716-C00037.png) 1975-10-20
BE825919A (fr) 1975-08-25
DK348678A (da) 1978-08-07
ES452915A1 (es) 1977-11-01
BG26201A3 (US06420036-20020716-C00037.png) 1979-02-15
SE431652B (sv) 1984-02-20
AU498131B2 (en) 1979-02-15
NZ176623A (en) 1978-04-03
ES435110A1 (es) 1977-03-16
IL46699A (en) 1977-11-30
SE438854B (sv) 1985-05-13
AT350068B (de) 1979-05-10
NO750625L (US06420036-20020716-C00037.png) 1975-08-27
IE40695L (en) 1975-08-26
DE2506330A1 (de) 1975-09-04
DD117074A5 (US06420036-20020716-C00037.png) 1975-12-20

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